Pharmaceutical Development

News

PBL’s Commitment to Erwinase® Supply and Quality

Stoppers & Vials

Over the past two years, PBL has made significant improvements to its operations and has been consistently manufacturing its life-saving product Erwinase® on schedule and to specification.

PBL is committed to providing this medicine for patients who need it.  PBL is confident in the consistent high quality of Erwinase® which is released by Qualified Persons, independently reviewed and continues to make batches available for collection on a regular basis.

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PBL Licenses Erwinase to Clinigen

3000 l fermentation hall

PBL announces that it has signed an exclusive, worldwide licensing agreement with Clinigen Group plc (“Clinigen”) for the distribution of Erwinase®/ Erwinaze® (“Erwinase”), the Company’s life-saving treatment for acute lymphoblastic leukaemia, a cancer of the blood predominantly affecting children. The agreement will become effective from January 1st 2021.

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Erwinase® sales in 2019 exceed $177 million

Erwinase fermentation

Porton Biopharma Limited (“PBL”), the UK biopharmaceutical, development and manufacturing company, notes yesterday’s full year financial results announcement from Jazz Pharmaceuticals PLC, which confirmed that Erwinase®, the Company’s life-saving cancer treatment, recorded sales of more than $177 million in 2019, up 2%.

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PBL supports winning iGEM team

winning iGEM team

PBL is proud to have provided support to a team of undergraduate students from Nottingham University who won a Gold Medal at this years international Genetically Engineered Machine (iGEM) competition.

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PBL gains approval to advance next generation anthrax vaccine to Phase 1 clinical trial

Clinical trial medic

Porton Biopharma Ltd (PBL) has today announced that it has signed a modification to its contract (HHSN272201600045C) with the US National Institute of Health’s National Institute of Allergy and Infectious Diseases (NIAID) to advance a next generation intra-nasal anthrax vaccine into the clinical-trial phase. The contract modification is worth US $4.5 million and follows approval by the US Food and Drug Administration (FDA) of the investigational new drug (IND) application

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PBL case study featured in July edition of Manufacturing Chemist

Purification expertise

In this case study, Dr David Gervais, Head of Product and Fermentation Development at Porton Biopharma  describes how a non-GMP enzyme manufacturing process has been successfully converted from a native to a recombinant one using bioinformatics and next-generation sequencing (NGS).

Demonstrating PBL’s capability to deliver significant improvements in yield, purity and activity for customer’s products.

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