Careers

Porton Biopharma has approximately 350 staff in a wide range of roles from those working in our pharmaceutical manufacturing plants, through to our quality and scientific development groups.  All focused on developing & manufacturing life-saving products that make a real difference to patients’ lives.

We are always looking for people, ranging from those with a general interest in science & technology, to ones with higher qualifications and/or experience.

This currently includes various vacancies for pharmaceutical production staff and supervisors to support our continued growth.  So if you are a motivated person who is interested in working in a high-tech environment as part of a dynamic team, then there could be a role for you.

 

 

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WE OFFER…

A friendly environment working alongside committed teams of people, who will be happy to share their knowledge and experience to allow you to develop your potential, with benefits that include:

  • a competitive salary
  • the necessary training
  • a pension scheme
  • 30 days annual leave
  • a canteen, gym and an active sports & social club
  • free on-site parking

With ongoing investment into the company and plans to increase our workforce, we are committed to being a leading life-science company that really makes a difference to patients’ lives.

To see the sort of  people that we ‘re looking for, the  Staff Profiles page has short interviews with current staff giving an overview of just some of our roles.

CURRENT VACANCIES…

PBL only accept CV’s from Recruitment Agencies with whom we have agreed Terms & Conditions.

A list of our current vacancies shown below.

To apply for a specific vacancy applicants should  send a covering letter quoting the Job Reference Number, a copy of their CV, together with a supporting statement referring to both the Job Description and Person Specification.

However, we also welcome applications from people with transferable skills that are looking for that next challenge and to develop their career.  To be considered for up-and-coming roles please send a covering letter indicating why you want to join PBL and in which area your career aspirations lie (Engineering  / Production  / Quality etc.),  along with a CV detailing your skills and experience which we can keep on file for when a suitable position becomes available.

All applications should be sent to recruitment@portonbiopharma.com.

WORK EXPERIENCE

As a business, we recognise the value that offering work-experience placements can bring and typically offer up to 4  one-week placements each year, usually in June.   All applicants must be over 16 years of age at the time of the placement, and will be chosen following a selection process.

If you are interested in applying, then send an email and covering letter stating your interest and giving reasons why we should choose you to business@portonbiopharma.com  Applications must be received by the end of November in order to be considered for the following summer’s places.

 

PBL551 Facilities Maintenance Technician

Salary: Circa £30,000 per annum

Closing Date: 29th November 2019

Reference Number: PBL551

The PBL Engineering group is responsible for provision of all engineering support within the highly regulated GMP Facilities at PBL Porton Down. This structure includes engineering functions provided by professional engineers specialising in clean rooms, GMP critical utilities, production equipment, Instrumentation and pharmaceutical facilities, and capital works delivery.

Job Summary…

Working within the PBL Engineering team you will assist in the undertaking of all aspects of facilities maintenance both planned and ad-hoc tasks. Tasks to be undertaken will be varied from small plumbing works, general building maintenance, painting and decorating, management of contractors when on site and conducting daily water sampling and routine checks.

With support you will be ensuring the site is maintained at all times across the production hall, offices, and outside areas. You will become a valued member of the engineering team and assist during maintenance activities as required. 

MAIN DUTIES AND RESPONSIBILITIES

  • Maintaining the appearance of PBL facilities by painting and decorating
  • Conducting repairs to the facilities by using basic carpentry and plumbing skills
  • Conducting daily maintenance tasks
  • Maintaining the grounds
  • Completing all paperwork as required to meet GMP standards
  • Looking after contractors when on site and ensuring they are operating according to the RAMS provided
  • A good understanding of Health and Safety
  • Be able to work in a controlled manner that meets Good manufacturing standards (GMP)

We are looking for…

The successful candidate will need to have experience in basic plumbing, decorating and carpentry, be flexible, proactive and able to work well within a team. A background working in a facilities/maintenance support role is essential and experience of working to GMP (Good Manufacturing Practices) is desirable.

For further information or an informal discussion about the post, please contact:

Stuart.naylor@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL410 Senior Production Technician (Seed)

Salary: £21700.00 per annum

Closing Date: 15th November 2019

Reference Number: PBL410

Job Summary………………..

The post holder will report to the Seed Room Supervisor. They will support the Seed Room Supervisor by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements. This role will involve undertaking a range of tasks, from preparation and use of operational equipment, seed culture manufacture, preparation of production medium, completion and review of Quality documentation, routine cleaning and environmental monitoring. Full training will be given where required, some cross training between units is required.

The post holder will…………

Be involved in the manufacture of life saving therapeutic vaccines. The post involves working in aseptic high-grade cleanroom environments manufacturing Erwinase working seed culture. The post also includes activities such as maintenance and monitoring of the facility, manufacture of media and completion of GMP records.

We are looking for……………….

Qualifications in GCSE Maths, English and Science are essential, further relevant qualifications or experience are desirable. The successful candidate will be an excellent communicator with good data entry skills, the ability to work well in a team and demonstrate problem solving abilities.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

To download the job description please click here

PBL411 Aseptic Processing Specialist

Salary: Starting salary £29,355 negotiable dependent upon experience

Reference Number: PBL411

Job Purpose…

This position will report to the Aseptic Processing Functional Manager and will provide technical specialist support to all aseptic processing activities in the manufacture of Erwinase, Anthrax vaccine and other PBL products. The role will work cross functionally and be involved in current projects, new projects and all manufacturing activities that require aseptic processing input. It is expected that the role will typically focus on day to day aseptic processing matters within Production but may also be required to support projects designed to improve and develop PBL’s aseptic processing strategy.

We are looking for…

An individual who is educated to degree level or equivalent in a relevant discipline. The successful candidate should have a minimum of 5 years’ experience within Biopharma / Pharma aseptic GMP environments and have an in depth understanding of aseptic processing and techniques. You will need to have an understanding of regulatory requirements for biological products and experience in the implementation of new technologies and equipment into GMP manufacture and will have proven experience of generating GMP documents within a quality system. Experience of delivering specialised technical training and report writing and data trending evaluation would be desirable but not essential. The successful applicant will have a flexible approach to work and be able to deliver to schedules.

The post holder will…

  • Lead in the day to day aseptic processing of PPL’s products.
  • Support the management and development of improved and new processing techniques in the various aseptic processing activities.
  • Provide technical support to production staff involved in the various aseptic processes.
  • Provide troubleshooting and technical support into process investigations.
  • Collate and share technical information with internal and external bodies to benefit the production methods, teams and departments.
  • Perform process mapping and process efficiency trending.
  • Provide specialist training to staff in aseptic processing techniques and theory.
  • Identify, evaluate and adapt new technologies where appropriate and ensure that the production area operates to a high standard and complies with GMP and other regulatory standards.
  • Assist colleagues in providing technical specialist input as required, in developing production and technical strategies for the units, identifying new opportunities as they arise and responding to external queries and complaints.
  • Contribute to reports and assist on the preparation of presentations, publications and liaison with customers, collaborators and licensing agencies.
  • Support the Functional Manager Aseptic Processing in pursuance of strategic improvements to aseptic processing control.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL442 Computer System Validation Specialist

Salary: Starting salary £42,230 negotiable dependent upon experience

Reference Number: PBL442

Job Purpose

This role is within the Facilities Validation Department and is responsible for the provision of subject matter expertise and the execution of Computerised System Validation activities.The Facilities Validation department supports cGMP manufacturing activities and is responsible for ensuring compliance to the cGMP guidelines.

This role reports into the Computer Systems Validation Manager and is responsible for the timely execution of Computer Systems Validation activities with respect to:

  • Writing (and reviewing) of validation protocols
  • Timely execution of CSV protocols with the subsequent generation of reports
  • Leading CSV compliance investigations with respect to Non-conformances and CAPAs
  • Performing CSV / Data integrity gap analysis and remediation activities.

The post holder will be expected to write, review and approve validation protocols, execute validation studies and write, approve validation reports associated with the qualification of Computerised systems and the introduction of new equipment into beneficial use.

The post holder will…

  • Take the lead in computer system validation and compliance, manage and deliver specific Validation Projects according to the business priorities, including work scheduling and supervision of junior members of staff.
  • Promote continuous improvement of validation systems and procedures to ensure efficiency and best practice within the industry and to stay abreast of changing regulatory expectations.
  • Write, review and approve validation documentation including protocols and reports and manage the timely closure of any discrepancies or non-conformities
  • Provide a reliable service to our internal customers to ensure that timescales are met, and work is carried out to meet expectations.
  • Maintain the ongoing compliant status of computer systems associated with equipment, facilities and utilities by involvement of the scheduling of activities.
  • Communicate validation activities with our internal and external customers and work with them to resolve problems and conflicts.
  • In line with overall responsibilities, perform additional tasks assigned by the line manager.
  • Undertake all work in accordance with Code of Safety Practice and site Quality Policies.

We are looking for…

The successful candidate will be educated to BTEC National Certificate level including Science or equivalent qualification or significant equivalent experience. A BSc in Engineering, Science or IT would be desirable but is not essential. You will need to have substantial experience of generation, execution and review of validation protocols, reports and technical documents as well as experience of validation life-cycle activities for computerised systems. The successful applicant will have extensive practical experience of working within a GMP quality system. Practical experience of working within a biopharmaceutical manufacturing environment would be desirable.

This is a hands-on role in a dynamic operating environment and the ideal candidate should be self-driven and capable of organising their own work-load. They should be comfortable liaising with stake-holders in order to deliver an effective documentation to an agreed time line and be confident to supervise junior staff.

For further information about the post, please contact: kevin.smart@portonbiopharma.com

To download the job description please click here

PBL485 QC Technologist (Monitoring and Training)

Salary: Starting salary £23,735 per annum negotiable dependent upon experience

Reference Number: PBL485

Job Purpose…

To provide specialist training in microbiological environmental monitoring methods, cleanroom gowning, aseptic practices and water sampling. The successful candidate will also be required to undertake microbiological environmental monitoring of critical pharmaceutical manufacturing operations to support the Sterility Assurance Program. To supervise, oversee, observe and qualify all production technologists and other staff where applicable, in gowning, microbiological environmental monitoring methods and water sampling.

We are looking for…

A candidate who has previous experience of working in cleanrooms, performing environmental monitoring and training of other members of staff to join the Environmental Monitoring Team within QC Biological Services. A degree in a relevant scientific discipline is desirable but not essential. The candidate should also have a good understanding of QC Microbiology laboratory testing. Applicants must have a flexible approach to working and be able to comply with SAPO regulations and must have a current valid right to work in the UK.

The post holder will…

  • Operate in compliance with cGMP.
  • Train and qualify all Production and other staff, as necessary, in the techniques and procedures for microbiological environmental monitoring.
  • Train and qualify all Production and other staff, as necessary, in water sampling.
  • Train and qualify all Production and other staff, as necessary, in procedures for gowning.
  • Oversee, supervise and observe Production and other staff undertaking environmental monitoring and water sampling to ensure continued compliance.
  • Re-qualify Production and other staff at a defined frequency, as required by GMP.
  • Plan and organise schedules for training, qualifications and observations.
  • Assess staff competence in environmental monitoring, water sampling and gowning procedures. Sign training documentation and produce certificates for trained members of staff.
  • Carry out and record microbiological environmental monitoring for critical manufacturing operations, and routine monitoring where required.
  • Input microbiological environmental monitoring and water sampling data into appropriate databases and spreadsheets.
  • Be involved in the writing and updating of Standard Operating Procedures relating to environmental monitoring and water sampling, either as the author, or by providing technical information and advice to the author.
  • Attend training courses that contribute to the efficiency of the operating systems and are beneficial to the post holder’s personal development.
  • Follow operating procedures at all times and ask for advice when necessary.
  • Undertake all work in accordance with Porton Down’s Code of Safety Practice and Quality Systems.
  • To prepare environmental summary reports of production processes for insertion into documents, reports and batch manufacturing records as part of batch release.
  • To investigate out-of-specification water and environmental monitoring test results in conjunction with the Compliance Team and review resulting Non-Conformances, participating in Ishikawa and 5-Whys investigations, where necessary.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL491 Visual Inspection Production Technician

Salary: Starting salary £20,220 per annum negotiable dependent upon experience

Reference Number: PBL491

Job Purpose…

This post is part of the Product Finishing team within PBL’s Pharmaceutical Production Unit which is responsible for duties including media and equipment preparation, assisting with purification and formulation of Erwinase Drug Substance, sterile filtration, and aseptic processing within a Good Manufacturing Process (GMP) department.

This post will involve training and qualification in the visual inspection process. Once qualified, the post will involve manual visual inspection of all Erwinase vials as part of the product finishing process. Other visual inspection processes will also be undertaken such as media simulation and lactose fills when required. The main responsibility of the role is within the visual inspection team however when time permits there will be opportunities to engage in other aspects within the production unit. The post holder will report to the Product Finishing Team Leader/supervisor.

The post holder will…

The visual inspection team performs the manual 100% visual inspection of Erwinase vials, a process which involves a visual assessment of final drug product vials and the removal of rejected material from the batch. Full training will be provided and once qualified you will work together as part of the team to undertake the visual inspection of all Erwinase batches manufactured. This activity will take up the majority of the time however there are opportunities between inspections to work alongside other production operators and become trained in other processes within the Production unit.

We are looking for…

The post holder will have a good general education and be educated to a minimum of NVQ 2 level in a relevant subject or equivalent level of qualification or significant equivalent proven experience as well as holding a GCSE in Mathematics, English & Science. The nature of this post requires individuals who can remain diligent and focused throughout the day. Candidates will have experience of working to deadlines, schedules and the ability to follow written procedures. Candidates need to have excellent attention to detail, be a good communicator and be able to work effectively as part of a team.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL498 Validation Technologist (Facilities & Utility)

Salary: Starting Salary £29,335 negotiable dependent upon experience.

Reference Number: PBL498

Job Purpose…

The Facilities Validation department supports cGMP manufacturing activities and is responsible for ensuring compliance to the cGMP guidelines on Validation activities.

The purpose of this role is to execute validation activities relating to Facilities and Utilities. This will involve coordination with Engineering, Production, QC and QA departments to ensure a timely delivery of the qualification report.

The post holder may be expected to supervise contractor resource where appropriate with responsibility to ensure adequate training and supervision is provided.

The post holder will be required to write, review and where appropriate approve validation reports prior to execution, followed by report generation. The core activities will include thermal and microbiological testing of:

  • Autoclaves (BSEN-285)
  • Depyrogenation ovens
  • Extraction Tanks
  • Centrifuges
  • Vessels
  • (but not limited to) the qualification of Facilities and Utilities.

The post holder will...

  • Generate, review (technical) and execute process validation protocols (thermal and microbiological testing)
  • Create Process validation reports
  • Use the Electronic Quality Management System (EQMS) to manage appropriate corrective action plans and report through the PBL non-conformance system, for failures/performance issues.
  • Write and review Risk assessments
  • Manage work schedule as planned by the validation schedule co-ordinator
  • Coordinate Contractor or permanent resources to deliver timely documentation in support of Process Validation activities
  • Ensure Process Validation procedures are aligned with regulatory requirements
  • Meet all internal regulatory training requirements (internal training provided)

We are looking for...

A person with at least 12 months hands-on validation experience, able to perform thermal mapping studies and write protocols and reports. A sound knowledge of the Validation Life cycle and documentation deliverables is an essential requirement.

Other
In addition to Utilities and Sterilisation validation activities the post holder will be expected to undertake any related validation activities deemed necessary by line management. This could include the generation of validation documentation in accordance with the full validation life cycle for equipment, utilities and facilities.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL492 Senior Production Technician PPC

Salary: Cira £20,200, dependant on experience

Reference Number: PBL492

Job Purpose…

This post is located within Zones1-4 of the Pharmaceutical Production Centre (PPC). PPC Zones 1-4 is dedicated to the manufacture of Erwinase within two manufacturing sub units the Therapeutics Protein Unit (TPU) and Product Finishing Unit (PFU), both units are GMP manufacturing facilities. TPU performs downstream purification of the therapeutic products and PFU performs aseptic processing and final fill, freeze drying and visual inspection of the product. The team is responsible for the production of pharmaceutical products, preparation of components and the operation of production equipment. Day to day tasks also include maintaining the facility via specialist cleaning procedures, monitoring environmental conditions and performing aseptic processes within a cleanroom environment.

The post holder will…

Report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring activities supporting manufacturing are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment, to completion of Quality documentation. Full training will be provided where required.

We are looking for…

Applicants should have a GCSE in Maths, English and Science. They should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. Candidates should be able to communicate clearly, possessing good writing and data entry skills. Candidates will need to have a flexible approach to work, be able to work effectively as part of a team as well as being proactive and able to work on their own initiative.

For further information about the post, please contact:recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL511 Production Technician

Salary: Cira £20,200, dependant on experience

Reference Number: PBL511

Job Summary...

The position is in the Immuno team who produce Anthrax Vaccine. The successful applicant will be responsible for manufacturing Anthrax Vaccine to cGMP standards as well as standard housekeeping tasks to keep the unit compliant

 The post holder will...

  • Perform a range of routine Production and some non-routine technical procedures and understand the rationale behind the procedures and practices.
  • Undertake all work in accordance with PBL’s Code of Safety Practice, Quality System and all other regulatory requirements.
  • Follow defined procedures, policies, rules, regulations and guidelines for all activities to ensure product meets the required standard.
  • Generate and review documentation with regard to Risk Assessments and cGMP to ensure compliance of the unit with all necessary regulations.
  • Work diligently at all times. Complete documentation and records accurately and to a high standard.
  • Ensure the unit is maintained in a compliant state. Work to cGMP following Standard Operating Procedures (SOPs) and Codes of Practice. Keep updated on new rules and regulations.
  • Perform and record environmental monitoring and water sampling in cGMP areas in accordance with documented procedures. Monitor and record air pressures and hot and cold facility temperatures.
  • Analyse information and make decisions based on assessment.
  • Assist validation department with validation protocols on equipment.
  • Maintain and use a variety of laboratory equipment.
  • Work with a range of hazardous and non-hazardous chemicals.
  • Be competent in and perform aseptic techniques.
  • Be qualified to work in a clean room environment and in containment level 3 suites.
  • Work accurately and with good hand eye co-ordination, sometimes for prolonged periods of time.
  • Operate autoclaves and sterilising ovens and have an appropriate level of understanding to review cycle data as a senior operator.

We are looking for…

A well organised person with good documentation skills and work ethic. Previous GMP experience will be beneficial but not essential as training will be provided.

For further information or an informal discussion about the post, please contact:

Graham Douglas on 01980 557102 or graham.douglas@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd to recruitment@portonbiopharma.com

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL522 Senior Production Technician - FPP

Salary: Starting salary £21,000 per annum, plus 30% shift enhancement

Reference Number: PBL522

Job Purpose…

This is a shift working role which will attract a salary enhancement once appointed. This Senior Production Technician post is located at Porton Down in the Fermentation Process Plant (FPP) current Good Manufacturing Practice (cGMP) pharmaceutical manufacturing facility. This facility produces therapeutic products by bacterial fermentation followed by initial phase downstream processing.

Therapeutic products produced at Porton are licensed and marketed for worldwide distribution. The FPP is undergoing significant investment and expansion as production is being increased to meet product demand.

We are looking for…

An applicant who has GCSE’s in Maths, English and Science or equivalent qualifications. In addition, they should also be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. Candidates should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. They should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

The post holder will…

Work a shift pattern which covers 24-hour, 7 day working. They will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be provided.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information about the post, please contact: recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL539 QC Microbiology Technologist

Salary: Circa £23,500

Reference Number: PBL539

Job Purpose…

The post holder will be part of the QC Bacteriology Technical Services team and assist with activities which include the following:

To undertake and perform microbiological QC analyses in the Quality Control Bacteriology Technical Services Unit, which provides specialist microbiological testing services in support of licensed pharmaceutical manufacture at PBL, Porton Down, in compliance with cGMP.

The post holder will…

  • Undertake and perform microbiological QC analyses in support of Porton Biopharma’s licensed production, service, validation and developmental programs
  • Carry out all work in compliance with cGMP
  • Test microbiological samples from all stages of the production processes of licensed and developmental products and to assess the results against pre-set standards and specifications
  • Undertake identification of micro-organisms isolated from microbiological tests and samples
  • Record all information and data clearly and accurately
  • Pre-test media used within QC and Production against pre-set specifications
  • Maintain the Bacteriology Technical Services Culture Collection, media stocks, and necessary consumables to ensure the efficient running of the group
  • Safely operate, clean and maintain laboratory equipment to the required levels of cleanliness and operating standards
  • Provide cover for and assist the Environmental Monitoring team when required

 We are looking for…

An applicant who has good interpersonal skills, is able to work as part of a team and is methodical and reliable with the ability to think clearly. The successful applicant will have the ability to learn and be able to respond to changes in schedule and demands. They will need to have knowledge and experience of microbiology gained in a laboratory or similar environment and ideally have experience of working in a Good Manufacturing Practice (GMP) or similarly regulated environment.

Key skills are:

  • Knowledge and experience of microbiology gained in a laboratory or similar environment
  • An understanding of GMP and quality systems
  • Able to work methodically and to strict deadlines
  • To perform routine testing within the microbiology laboratory, on a day to day basis, of the Bacteriology Technical Services Unit.
  • Good understanding of QC microbiological assays and QC laboratory systems
  • Confident to train junior staff in processes and procedures

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL537 Cleaning Validation Technologist

Salary: Circa £35,000 negotiable dependant on experience.

Reference Number: PBL537

Job Summary...

The Cleaning Validation team within the Validation Department supports the development and validation/qualification of manufacturing equipment cleaning processes. This includes both the validation of new or amended cleaning processes, and the ongoing routine cleaning verification of existing and validated cleaning processes.

This role is to execute the timely completion of cleaning validation studies in support of PBL manufacturing activities and regulatory requirements. The role will include the writing, review and execution of cleaning validation/verification protocol documents and reports, the coordination of support activities and resources to deliver on time a high standard of documentation.

The position holder will be expected to attend project group meetings, liaise with PBL support teams and peers to establish data for inclusion within protocols and reports.

The position holder should be prepared to execute and witness cleaning validation/verification studies in line with the Production schedule.

There will be a requirement to support other validation activities (e.g. Process Validation) on a temporary basis.

 The post holder will...

  • Write, review and execute cleaning validation/verification protocol documents.
  • Write cleaning validation/verification reports, where required.
  • Write, review and execute cleaning development documentation.
  • Deliver assigned cleaning development, validation and verification activities on time in accordance with the Site Validation Master Plan (VMP).
  • To deliver on non-conformance, action item, change control (CC) and CC actions on time.
  • Participate in assigned GEMBA meetings/activities, as required

We are looking for...

An enthusiastic candidate who can communicate effectively at all levels, and across multi-disciplinary teams, to support the completion of cleaning validation and cleaning verification activities to satisfy compliance and regulatory commitments, in addition to the continuous improvement of equipment cleaning processes at PBL.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

 

To download the job description please click here

PBL542 QC Microbiology Compliance Officer

Salary: Circa £27,000 per annum, dependant on experience

Job Purpose / Summary

The purpose of this role is to provide support for the QC Microbiology department at Porton Biopharma. This will include compilation of compliance documentation, including deviations, non-conformances and CAPA, change controls, protocols and reports. The holder will also to undertake and perform microbiological QC analyses in compliance with cGMP.

The post holder will…………

  • Write and review Standard Operating Procedures, protocols and reports in accordance with regulatory requirements.
  • Investigate, write and review non-conformances and deviations raised in accordance with regulatory requirements.
  • Complete departmental CAPAs and to implement any required quality improvements that may arise from this.
  • Identify and implement quality improvements within the department pro-actively.
  • Carry out change management, raising, writing and reviewing change controls.
  • Assist as a member of the QC Microbiology Team, on a day to day basis, of the Bacteriology Technical Services Unit.
  • Test microbiological samples, working at ACDP Containment level 2 and at Containment Level 3, when required, from all stages of the production processes of products manufactured at PBL, Porton Down and to assess the results against pre-set standards.
  • Record and assess results from environmental and water sampling and carry out preliminary and confirmatory identification of micro-organisms.

 We are looking for……………….

A candidate with significant experience of working to cGMP, with a significant knowledge of pharmaceutical Quality Assurance. The candidate must have experience in writing and reviewing discrepancies, procedures, change controls and CAPAs. The candidate should have a significant level of experience of working within ACDP containment level 2 microbiology laboratories.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL549 Development Placement Student

Salary: £20,000 per annum

Closing Date: 6th December 2019

Reference Number: PBL549

Job Summary

The Development Group is a development and technology transfer group playing a key role in the translational research activities of the site. Its role is to develop manufacturing processes and associated analytical methods for use in the cGMP production of biotherapeutics and healthcare interventions. Projects may comprise the development of research designs and/or the improvement of existing commercial processes. The department is organized into 4 core teams with responsibility for product development, in vitro culture processes, downstream purification processes and analytical method development.

The post-holder will contribute to the activities of the group by providing support in the development of production processes for biopharmaceutical products within ISO 9001 laboratories.

We are looking for an individual with an interest in a number of scientific and technical skills the area of the cloning, culturing and growth of prokaryotic organisms, downstream processing and biological assay development.The post holder will be currently enrolled in, and have completed the second year of a science degree in a relevant biological science at a university that supports placement students.

For further information or an informal discussion about the post, please contact:

Dr Dave Gervais 01980 551759

Applications should be e-mailed, along with a covering letter explaining your interest in the role, to dave.gervais@portonbiopharma.com. We also strongly suggest including with your application a letter of reference from an academic tutor explaining your suitability for the placement.

Applicants are strongly advised to explain in their application both their interests in the role, and how they meet criteria described above.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL550 QMS Document Control - Training Administrator (Fixed Term 12 Month)

Salary: £20200.00 per annum

Closing Date: 22nd November 2019

Reference Number: PBL550

Job Summary.....

To assist with the daily operation of the Porton Biopharma Ltd. Documentation Control team

The post holder will.....

Work with minimal supervision, to strict deadlines, methodically and to a high degree of accuracy to maintain records and filing systems to ensure adequate control of documents.

Performance of additional general office and administrative duties to support the activities of QA Groups e.g. filing, archiving, ordering supplies etc.

The successful candidate will have 5 GCSEs or equivalent including English, Maths and a scientific subject. In addition, an RSA 3 in typing, word processing or a European Computer Driving License (ECDL) or equivalent would be beneficial.

Additional experience in an administrative role (general office work) and previous use of Computer based software systems, including the Microsoft Office suite and Windows based databases and spreadsheets would be an advantage.

We are looking for.....

An applicant who has excellent communication skills in addition to good customer focus with a drive and determination to succeed in maintaining the current exceptional service levels. Using strong organisational and data entry skills the successful applicant will work within a small team to maintain a critical aspect of the site’s Quality Management System (Document Control and Archive Service).

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here