Careers

Porton Biopharma has approximately 400 staff in a wide range of roles from those working in our pharmaceutical manufacturing plants, through to our quality and scientific development groups.  All focused on developing & manufacturing life-saving products that make a real difference to patients’ lives.

We are always looking for people, ranging from those with a general interest in science & technology, to ones with higher qualifications and/or experience.

This currently includes various vacancies for pharmaceutical production staff and supervisors to support our continued growth.  So if you are a motivated person who is interested in working in a high-tech environment as part of a dynamic team, then there could be a role for you.

Laboratory

 

Training

 

Freeze Dryer

 

Quality Control

WE OFFER…

A friendly environment working alongside committed teams of people, who will be happy to share their knowledge and experience to allow you to develop your potential, with benefits that include:

  • a competitive salary
  • the necessary training
  • a pension scheme
  • 30 days annual leave
  • free on-site parking

With ongoing investment into the company and plans to increase our workforce, we are committed to being a leading life-science company that really makes a difference to patients’ lives.

To see the sort of  people that we ‘re looking for, the  Staff Profiles page has short interviews with current staff giving an overview of just some of our roles.

CURRENT VACANCIES…

PBL only accept CV’s from Recruitment Agencies with whom we have agreed Terms & Conditions.

A list of our current vacancies shown below.

To apply for a specific vacancy applicants should  send a covering letter quoting the Job Reference Number, a copy of their CV, together with a supporting statement referring to both the Job Description and Person Specification.

However, we also welcome applications from people with transferable skills that are looking for that next challenge and to develop their career.  To be considered for up-and-coming roles please send a covering letter indicating why you want to join PBL and in which area your career aspirations lie (Engineering  / Production  / Quality etc.),  along with a CV detailing your skills and experience which we can keep on file for when a suitable position becomes available.

All applicants should check our Recruitment Privacy Policy and all applications should be sent to recruitment@portonbiopharma.com.

WORK EXPERIENCE

As a business, we recognise the value that offering work-experience placements can bring and typically offer up to 4  one-week placements each year, usually in June.   All applicants must be over 16 years of age at the time of the placement, and will be chosen following a selection process.

If you are interested in applying, then send an email and covering letter stating your interest and giving reasons why we should choose you to business@portonbiopharma.com  Applications must be received by the end of November in order to be considered for the following summer’s places.

PBL546 QMS Documentation Controller & GxP Archivist (Fixed Term 12mth)

Salary: Circa £20,500.00 per annum, dependant on experience

Closing Date: 23rd April 2021

Reference Number: PBL546

An exciting opportunity has arisen for a QMS Documentation Controller and GxP Archivist to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The QMS Documentation Controller and GxP Archivist will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Quality Assurance Documentation Team who are responsible for the administration of documentation within the EQMS System and provide a variety of Document Control functions / services which include document creation, formatting, scanning and controlled distribution of PBL documents

The post holder will: Work with minimal supervision, to strict deadlines, methodically and to a high degree of accuracy to maintain records and filing systems to ensure adequate control of documents. Performance of additional general office and administrative duties to support the activities of QA Groups e.g. filing, archiving, ordering supplies etc.

We are looking for: An applicant who has excellent communication skills in addition to good customer focus with a drive and determination to succeed in maintaining the current exceptional service levels. Using strong organisational and data entry skills the successful applicant will work within a small team to maintain a critical aspect of the site’s Quality Management System (Document Control and Archive Service).

Key responsibilities

  • To manage and maintain the necessary tracking system(s) / database(s)
  • To liaise with internal customers to ensure efficient and effective processing of Quality Documentation and resolution of customer queries
  • Make decisions on processing Quality Documentation based on content and as guided by SOPs
  • Use computerised systems including inputting multiple critical data entries which require a high degree of accuracy
  • Provision of first line support, via email, telephone or face-to-face, with service users to ensure compliance with defined processes and effective processing
  • Provision of training both to individuals and groups, including the generation and assessment of training materials
  • To provide general office administrative support to the team, e.g. Filing, photocopying, stock control, arranging meetings, room bookings, car hire etc.

Person Specification

  • Have current right to work in the UK;
  • 5 GCSEs or equivalent, including English, Maths and a Scientific subject.
  • Previous experience of working in an administrative environment using computerised data systems, document control or archive experience.
  • Working knowledge of Microsoft Office, including Word and Excel.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL587 Production Technician (PPC)

Salary: Circa £20,200.00 per annum, dependant on experience

Reference Number: PBL587

An exciting opportunity has arisen for a Production Technician to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Production Technician will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the team within the manufacturing area responsible for the downstream processing, formulation and filling and freeze drying of Erwinase, who are responsible for the production of pharmaceutical products, preparation of components and the operation of production equipment. Day to day tasks also include maintaining the facility via specialist cleaning procedures, monitoring environmental conditions and performing aseptic processes within a cleanroom environment. As a Production Technician for Porton Biopharma, the post holder will be required to be able to carry out the key responsibilities:

Key responsibilities

  • Be responsible to the Unit Supervisor for your day to day activities.
  • Undertake all work in accordance with Code of Safety Practice, Quality System and all other regulatory requirements.
  • Follow all Procedures, Policies, Rules, Regulations and Guidelines for all activities to ensure products meet the required standard.
  • Take care and pay detailed attention to all tasks at all times. Complete documentation and records accurately and to a high standard.
  • Work to cGMP ensuring the unit is maintained in a compliant state following Standard Operating Procedures (SOPs) and codes of practice. Keep updated on new rules and regulations.
  • Maintain production areas to the required standard using defined cleaning procedures.
  • Perform and record environmental monitoring in cGMP areas in accordance with documented procedures. Take waters samples and complete relevant documentation. Monitor and record air pressures and hot and cold facility temperatures.
  • Perform a wide range of routine and some non-routine technical procedures and understand the rationale behind the procedures and practices.
  • Maintain and use a variety of laboratory equipment.
  • Work with a range of hazardous and non-hazardous chemicals.
  • Be competent to work in a clean room environment
  • Work accurately with good hand eye co-ordination. Sometimes for prolonged periods of time.
  • To assist in activities relating to the cGMP manufacturing of pharmaceutical products i.e. Prepare media, buffers and reagents both sterile and non-sterile. Packing and sterilisation of general and specialised equipment.
  • Work as part of a team.
  • Undertake general housekeeping duties e.g. rotation of stock, preparation of cleanroom clothing, cleaning of glassware and equipment.
  • Stock control of consumable. Order consumables from internal stores and external suppliers.
  • Communicate effectively with a variety of staff in a range of matters. To give, receive and relay information.
  • Liaise with other production areas to ensure efficient running of the unit. On occasion the post holder may be requested to work overtime.

Person Specification

  • Have current right to work in the UK;
  • GCSE (A-C) in Maths, English and Science
  • Ability to follow established written procedures
  • Accurate and clear record keeping skills
  • Good Numeracy and methodical approach
  • Be able to work to strict deadlines

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL588 Senior Production Technician (PPC)

Salary: Circa £20,200.00 per annum dependant on experience

Reference Number: PBL588

An exciting opportunity has arisen for a Senior Production Technician to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Senior Production Technician will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the PPC Team in Production who are responsible duties including media and equipment preparation, assisting with purification and formulation of Erwinase drug substance, sterile filtration, and aseptic processing. The team is responsible for the production of pharmaceutical products, preparation of components and the operation of production equipment. Day to day tasks also include maintaining the facility via specialist cleaning procedures and monitoring environmental conditions within a cleanroom environment.

As a Senior Production Technician for Porton Biopharma, the post holder will the post holder will report to the Production Supervisors, and the Unit Team Leader. He/she will support the Production Supervisors to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements. This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment, to completion of Quality documentation. Full training will be given where required

 

Key responsibilities

  • Be responsible to the Unit Supervisor for your day to day activities.
  • Undertake all work in accordance with Code of Safety Practice, Quality System and all other regulatory requirements.
  • Follow all Procedures, Policies, Rules, Regulations and Guidelines for all activities to ensure products meet the required standard.
  • Always take care and pay detailed attention to all tasks. Complete documentation and records accurately and to a high standard.
  • Work to cGMP ensuring the unit is maintained in a compliant state following Standard Operating Procedures (SOPs) and codes of practice. Keep updated on new rules and regulations.
  • Maintain production areas to the required standard using defined cleaning procedures.
  • Perform and record environmental monitoring in cGMP areas in accordance with documented procedures. Take waters samples and complete relevant documentation. Monitor and record air pressures and hot and cold facility temperatures.
  • Support junior staff in their activities and ensure they are adequately trained in all operational processes required.
  • Be responsible to the Unit Supervisor for the day to day operations of the Unit and, if required, to deputise in their absence.
  • Undertake all work in accordance with the Code of Safety Practice, Quality System and all other regulatory requirements.
  • Follow all Procedures, Policies, Rules, Regulations and Guidelines for all activities to ensure products meet the required standard.
  • Generate documentation with regard to risk assessments and cGMP to ensure compliance of the Unit with all necessary regulations.
  • Complete documentation and records accurately and to a high standard.
  • Work to cGMP ensuring the unit is maintained in a compliant state following Standard Operating Procedures (SOP’s) and codes of practice. Keep updated on new rules and regulations.
  • Maintain production areas to the required standard using defined cleaning procedures.
  • Perform and record environmental monitoring in cGMP areas in accordance with documented procedures. Take waters samples and complete relevant documentation. Monitor and record air pressures and hot and cold facility temperatures.
  • Analyse information and make decisions based on assessment.
  • Execute Validation Protocols on equipment.
  • Perform a wide range of routine and some non-routine technical procedures and understand the rationale behind the procedures and practices.
  • Maintain and use a variety of specialised equipment.

Person Specification

  • Have current right to work in the UK;
  • GCSE in Maths, English and Science or equivalent qualifications. In addition, applicants should be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience
  • Have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture
  • be able to communicate clearly, possessing good writing and data entry skills.
  • a flexible approach to work, be able to work effectively as part of a team, and be proactive and able to work on their own initiative when required

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL600 Senior Production Technician FPP/B01

Salary: Circa £20,200.00 per annum, dependant on experience, plus 30% shift enhancement

Reference Number: PBL600

An exciting opportunity has arisen for a Senior Production Technician to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Senior Production Technician will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Production Division as a Senior Production Technician for Porton Biopharma. This is a shift working role which will attract a salary enhancement once appointed. This Senior Production Technician post is located at Porton Down in the Fermentation Process Plant (FPP) current Good Manufacturing Practice (cGMP) pharmaceutical manufacturing facility. This facility produces therapeutic products by bacterial fermentation followed by initial phase downstream processing. Therapeutic products produced at Porton are licensed and marketed for worldwide distribution. The FPP is undergoing significant investment and expansion as production is being increased to meet product demand.

Candidates should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. They should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

The successful candidate will work a shift pattern which covers 24-hour, 7 days working. They will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements. This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large-scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be provided.

Key responsibilities

  • Working in an automated chemical plant.
  • Operate plant and equipment using newly installed automated control systems.
  • Ensure that the various work areas are maintained at the highest state of readiness at all times.
  • Ensure that their daily activities are coordinated with other team members.
  • Work within a GMP quality system.
  • Ensure that documentation is completed within the legal frameworks.
  • Take responsibility for Non-Conformances, CAPA, Risk Assessments and Change Controls for the area and ensure SOPs and BMRs are available for use.

Person Specification

  • Have current right to work in the UK;
  • GCSE’s in in Maths, English and Science or equivalent qualifications
  • A minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience
  • Worked within a manufacturing environment and with the Quality systems associated with cGMP manufacture.
  • Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL616 QMS & Compliance Lead

Salary: Circa £65,000.00 per annum, dependant on experience

Closing Date: 23rd April 2021

Reference Number: PBL616

An exciting opportunity has arisen for a QMS & Compliance Lead to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The QMS & Compliance Lead will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking and easy access to London and the south coast;
  • Onsite canteen;
  • Onsite nursery.

The successful candidate will be joining the Quality Management Team. As a QMS & Compliance Lead for Porton Biopharma you will assist with the delivery of autonomous and innovative leadership.

Key responsibilities

  • Lead the QMS & Compliance teams to deliver compliant Quality systems, and develop a world-class QMS;
  • Provide operational direction and leadership to a large team of GMP Quality professionals, Documentation control, & Archivist staff;
  • Develop and manage the QA, GMP, & QMS programmes, policies, standards, and procedures to ensure conformance to the highest standards and regulatory agency requirements (MHRA, EU, FDA etc.);
  • Establish processes and systems that support collaboration, compliance and are simple and effective;
  • Lead and support where required with regulatory inspections;
  • Further develop, implement and manage processes that align with, and drive, effective systems for change control, deviations and investigations, complaints, recalls, risk management and CAPA;
  • Oversee GMP Quality system performance metrics, analyse compliance data and coordinate the necessary Quality reporting and escalation responses;
  • Manage the processes for the Quality Management Review Board, Change Control Review Board and Risk Management forums;
  • Provide expertise and guidance to senior management in the interpretation of global GMP regulations, ICH guidelines and internal policies and procedures;
  • Promote continuous improvements in quality systems and department infrastructure; assist with creation/revision of appropriate SOPs, Code of Practices, Policies & Key Quality documents;
  • Train, manage, and mentor QMS, GMP, & QA staff for the effective performance in PBL cGMP processes & compliance activities.

Person Specification

  • Have current right to work in the UK;
  • Experience managing in a successful business;
  • Proven Leadership and Management skills in a matrix management environment;
  • Practical understanding and working knowledge of GMP regulations and Compliance requirements, with the ability to provide applicable guidance;
  • Extensive experience in the pharmaceutical or biotech industry, with extensive GMP QA experience within the FDA and/or EMA regulated environment;
  • Demonstrable experience of GMP QA management of a team of QA Professionals;
  • Comprehensive working knowledge of local, state, federal and international cGMP regulations; FDA/EU/ICH guidelines; validation standards, QMS and quality risk management principles;
  • Proven experience with leading and hosting successful regulatory audits;
  • Ability to resolve complex problems where analysis of situations or data requires an in-depth evaluation of various factors;
  • Self-motivated and able to prioritize projects in a fast-paced environment.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL630 Senior Analytical Scientist

Salary: Circa £25,000 negotiable dependant on experience

Closing Date: 23rd April 2021

Reference Number: PBL630

An exciting opportunity has arisen for a Senior Analytical Development Scientist to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Senior Analytical Development Scientist will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Analytical Method Development Team, which develops and performs analytical methods to support the manufacturing of biopharmaceutical products. These methods are used to characterise existing manufacturing processes, to guide process improvements and to support the introduction of new processes. As a Senior Analytical Development Scientist for Porton Biopharma, the post holder will be involved in leading the development, optimisation, validation and implementation of analytical methods for existing and pipeline products. He or she will be responsible for coordinating technical transfer of assays to QC and supporting routine testing activities of samples provided by other groups within PBL.

Key responsibilities

  • Lead the development of methods for the analysis of biopharmaceuticals from feasibility, through method development and qualification, to routine use within the Development group and/or transfer to QC.
  • Taking ownership of projects ensuring appropriate methods, assays, techniques and systems are implemented and utilised to meet project targets.
  • Fully documenting all analytical testing in worksheets associated with standard protocols or in the electronic laboratory notebook (ELN). Writing protocols, reports and study plans as required.
  • Taking responsibility for the supervision and training of staff where appropriate.
  • Establishing links and collaborations within and outside Porton Biopharma as necessary to benefit the project and/or department.
  • Maintaining awareness of Industry and International Regulatory Standards and guidance and
  • implementing where appropriate.

 Person Specification

  • Have current right to work in the UK;
  • Degree in relevant subject;
  • Practical experience of developing, optimising, validating and implementing protein analysis methods, ideally in a biopharmaceutical setting;
  • Experience in a range of protein-based analytical methods such as HLPC, UPLC, UV/VIS spectroscopy, Immunoassays and 2D electrophoresis;
  • Experience of managing projects, driving and delivering milestones to set deadlines;
  • Excellent written and verbal communication skills;
  • Experience of working to GMP and or ISO9001:2015 standards.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL622 QA Officer (Engineering & Validation Capital Projects)

Salary: Circa £36,460.00 per annum, negotiable dependant on experience

Closing Date: 23rd April 2021

Reference Number: PBL622

An exciting opportunity has arisen for a Permanent Quality Assurance Officer (Capital Works) to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Quality Assurance Officer (Capital Works) will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Quality Assurance Department, who are responsible for the management of the non-conformance and CAPA systems to support the manufacturing and testing of pharmaceutical products to GMP, the management of change control and risk management systems, the management for the internal and supplier audit management programmes, the management of the product review process the management of QA environmental compliance and the provision of QA oversight of manufacturing and testing activities. As a Quality Assurance Officer (Capital Works) for Porton Biopharma, the post holder will support Capital Works and other projects across multiple departments within PBL, ensuring that all activities are compliant and that required reviews are completed in a timely manner. In addition, the post holder will provide support to departmental In Process Teams (IPT) by performing all duties associated with the release of pharmaceutical products.

Key responsibilities:

  • To support the co-ordination and planning of project workload, ensuring Quality matters are considered and acted upon in a compliant fashion.
  • To actively participate in Quality investigations, change controls and risk assessments associated with the projects to ensure Quality considerations are taken into account.
  • To facilitate and lead structured investigations using recognised models such as “5 Whys” and “FMEA”.
  • To perform the review and approval of a number of key documents associated to the projects including but not limited to validation, SOPs, change controls, investigations, risk assessments, pre manufacturing checks, facility release.
  • To perform review of batch manufacturing records and release relevant material for the next stage of manufacture.
  • To provide appropriate QA oversight of manufacturing and testing processes within the projects to support the business (including occasional out of hours).
  • To participate in the data gathering/review for the quarterly trending reports and annual PQR.
  • To provide training and coaching to more junior members of the team and to staff from other departments in order to promote a quality culture.
  • To promote and enforce data integrity compliance across PBL.
  • To liaise with customers, consultants and contractors as required.
  • To provide support for departmental IPTs as required by performing all duties associated with the release of biopharmaceutical products.
  • To escalate relevant issues to line management and/or to the QP.
  • To provide KPI reports measuring the performance of the team.
  • To undertake relevant training.
  • To undertake work in accordance with the PBL Health and Safety policies and procedures and to work within any Quality Systems that are applicable to the site.
  • To comply with PBL policies and procedures and core values and behaviours.

Person Specification

  • Have current right to work in the UK;
  • Possess a good standard of written and spoken English;
  • Be educated to degree level or HND in relevant subject (e.g. Microbiology, or a related subject) or a demonstrable equivalent level of experience of working at a similar level in specialist area.
  • Experienced in operating quality systems in a GMP environment with proven evidence of encountering a wide range of situations.
  • Experience of preparing and providing accurate documents and reports in a timely fashion.
  • Extensive experience of using an eQMS system in a QA environment.
  • Excellent proven communication, tenacity and interpersonal skills.
  • Ability to work with a minimum of supervision & to prioritise own work
  • Strong customer focus
  • Excellent personal effectiveness
  • Excellent technical writing
  • An understanding of and commitment to equality of opportunity and good working relationships, both in terms of day-to-day working practices, but also in relation to management systems

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

 

To download the job description please click here

PBL621 Senior Production Technician (B20 - 37.5 hours per week)

Salary: Circa £20,200 per annum, dependant on experience

Reference Number: PBL621

An exciting opportunity has arisen for a Senior Production Technician to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Senior Production Technician will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Seed Production Unit, who are responsible for manufacturing Erwinase working seed cultures. As a Senior Production Technician for Porton Biopharma, the post holder will work in aseptic high-grade cleanroom environments to manufacture product, as well as maintaining and monitoring the facility and completing critical GMP records.

Key responsibilities

  • Manufacture of Erwinase working seed cultures
  • Preparation of media and equipment for use in manufacturing
  • Completion of GMP records to a high standard
  • Monitoring and maintaining the facility
  • Following company standard operating procedures (SOPs) and codes of practice

Person Specification

  • Have current right to work in the UK;
  • Be able to achieve UK government security clearance at SC level
  • GCSE in Maths, English and Science
  • Have an interest in working in within a GMP manufacturing environment
  • Strong communication and written skills

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL620 Technical Support Specialist - Microbiologist

Salary: £36,460.00 per annum

Closing Date: 23rd April 2021

Reference Number: PBL620

An exciting opportunity has arisen for a Technical Support Specialist with a microbiological background to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Technical Support Specialist (Microbiologist) will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Technical Operations team, who are responsible for providing technical input and support across all manufacturing facilities. The Technical Operations department is essentially a support function to site manufacturing and is engaged with all site capital projects, continuous improvement initiatives, investigations, technical reports and the introduction of new technologies. As a Technical Support Specialist for Porton Biopharma, the post holder will be part of a broader Technical Support team and be assigned as an integrated process team member within a key manufacturing unit. The post holder will provide microbiological advice, guidance, support and deliver improvements to the existing process and environment. Investigations, deviations and reports will be delivered to a high standard and within agreed timelines. The individual will be responsible for all microbiological issues and activities associated with the facility.

Key responsibilities

  • Be the IPT point of contact for all issues related to environmental monitoring and sterility assurance.
  • Be the lead investigator for all microbiological related issues.
  • Deliver investigations, action items, reports on time and in full.
  • Deliver improvements to agreed timelines.
  • Provide advice, support and recommendations for improvement.

Person Specification

  • Have current right to work in the UK;
  • Educated to degree level (Microbiology)
  • Experience in Biotech / Pharma industry
  • Working experience / exposure within classified manufacturing cleanrooms
  • Excellent report and communication skills

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL629 Analytical Method Development Lead

Salary: Circa £30,000.00 per annum, dependant on experience

Closing Date: 16th April 2021

Reference Number: PBL629

An exciting opportunity has arisen for an Analytical Method Development Lead to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Analytical Method Development Lead will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Analytical Method Development Team, who are responsible for [which develops and performs analytical methods to support the manufacturing of biopharmaceutical products. These methods are used to characterise existing manufacturing processes, to guide process improvements and to support the introduction of new processes. As a Method Development Lead for Porton Biopharma, the post holder will co-ordinate the activities of a team of analytical scientists to undertake analytical method development projects. They will also be required to act as a scientific lead for a range of analytical methods including chromatography and biological tests such as UV/VIS spectrometry. The post holder will also ensure that their team complies with Quality and Health & Safety policies, processes and procedures. The candidate will also be required to take on management responsibilities for their team such as appraisals, recruitment and performance management.

Key responsibilities

  • To be responsible for line management of staff including scientific management, performance management, supervision, training and recruitment.
  • Co-ordinate and manage project activities across Development functional groups and Production and where appropriate Research teams.
  • To identify, evaluate, adapt and introduce new analytical technologies where appropriate, providing sound scientific study to ensure such technologies are fit for purpose and cost effective.
  • To take responsibility for the analytical development work packages as assigned by the Line Manager: design, initiation, monitoring and implementation.
  • Ensuring that testing and reporting of results, generated from routine analysis, occur in a timely manner.
  • To review and check data to ensure accuracy and compliance to processes and procedures within set deadlines.

Person Specification

  • Have current right to work in the UK;
  • Degree in a relevant subject as well as an MSc. or PhD.;
  • Practical experience of developing, optimising, validating and implementing protein analysis methods, ideally in a biopharmaceutical setting;
  • Experience in a range of protein-based analytical methods;
  • Experience of managing projects, driving and delivering milestones to set deadlines;
  • Management and Leadership skills;
  • Excellent written and verbal communication skills;
  • Experience of working to GMP and or ISO9001:2015 standards.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL632 Assistant Compliance Engineer (FT 12mths)

Salary: £23,200.00 per annum

Closing Date: 26th March 2021

Reference Number: PBL632

An exciting opportunity has arisen for an Assistant Compliance Engineer to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Assistant Compliance Engineer will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Engineering Directorate, who are responsible for the provision of all engineering support within the highly regulated GMP facilities at PBL Porton Down. As an Assistant Compliance Engineer for Porton Biopharma, the post holder will principally be responsible for the sampling of critical utilities such as Clean Steam Condensate, Water for Injection and Purified Water within Engineering-controlled service areas, additionally the post holder will be responsible for maintaining the Engineering O&M (Operations and Maintenance) manual archives, ensuring any equipment manuals are accounted for. Furthermore, the role will include the opportunity to be involved with wider compliance activities within the Engineering directorate.

Key responsibilities

  • To routinely perform and document the aseptic sampling of critical utilities including, purified water, water for injection and clean steam, within the plant rooms of two manufacturing facilities. To ensure utility compliance for manufacturing of pharmaceutical products.
  • To supervise third party water samplers assuring that the samples have been collected correctly and PBL procedures are adhered to.
  • To escalate any sampling compliance issues to the compliance and Quality Engineers, ensuring that utility equipment can be maintained.
  • To archive and maintain a library of operations and maintenance manuals for the Engineering department.
  • To provide backup support to the Compliance Engineers and Quality Engineer.

 Person Specification

  • Have current right to work in the UK;
  • 5 GCSE’s or equivalent to include English, Maths and Science
  • A good standard of written and spoke English Language
  • Previous experience of working to written procedures or safety risk assessments
  • Working knowledge of Microsoft Office. Including Word and Excel

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL634 Compliance Engineer

Salary: Circa £29,355.00 per annum, dependant on experience

Closing Date: 2nd April 2021

Reference Number: PBL624

An exciting opportunity has arisen for a Compliance Engineer to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Compliance Engineer will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Engineering Division, who are responsible for provision of all engineering support within the highly regulated GMP facilities at PBL Porton Down. This structure includes engineering functions provided by predominantly chartered professional engineers specialising in clean rooms, GMP critical utilities, production equipment, pharmaceutical facilities, and capital works delivery. As a Compliance Engineer for Porton Biopharma, the post holder will contribute to the compliance of GMP manufacturing operations as part of an Integrated Process Team (IPT) including Engineering, Production and Quality representatives.

Key responsibilities

  • To lead the investigation and root cause analysis determination of deviations as part of a multidisciplinary team
  • Support engineering colleagues to complete continuous improvement actions and the timely completion of compliance activities
  • Assist in fault finding following failures or performance issues and the coordination of planned and corrective engineering activities such as maintenance and calibration
  • To monitor the performance of critical systems supporting manufacturing including HVAC and critical utilities

 Person Specification

  • Have current right to work in the UK;
  • Educated to at least A/AS (or equivalent) and preferably to degree level (or equivalent) in a science or engineering based subject or has completed an appropriate Engineering apprenticeship
  • Previous practical experience of leading Root Cause investigations either solely or in a team.
  • Experience of working with a GMP Quality System using systems such as Good Document Practice, Change Control, Non Conformance management and CAPA implementation
  • Possess technical writing skills relating to the creation of GMP documents, technical investigation reports, testing protocols and/or standard operating procedures.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL635 Calibration Supervisor

Salary: Circa £35,000 negotiable dependant on experience.

Closing Date: 2nd April 2021

Reference Number: PBL635

An exciting opportunity has arisen for a Calibration Supervisor to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Calibration Supervisor will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Calibration Team, who are responsible calibration and compliance testing of instruments and facilities to support both Production and Development. As a Calibration Supervisor for Porton Biopharma, the post holder will ensure all calibration and compliance testing activities under the position’s responsibility are delivered in a timely manner in order to prevent delay to production. They will Lead, motivate and manage the development of the Pharmaceutical Engineering Calibration Team and provide expertise in a cross functional group responsible for the delivery of compliance within Porton Biopharma (PBL). This role involves interfacing with equipment/system owners, the scheduling team, the principle maintenance contractor, capital project managers and the Quality Departments to ensure compliance is maintained with current Good Manufacturing Practice.

Key responsibilities

    • Lead, motivate and manage the development of the Pharmaceutical Engineering Calibration Team and provide expertise in a cross functional group responsible for the delivery of compliance within Porton Biopharma (PBL).
  • Day to day management of calibration activities and associated resource planning to meet the requirements of defined schedules through weekly scheduling meetings and shutdown meetings.
  • Completion of calibration assessments.
  • Generation of non-conformance documentation.
  • Lead the development and implementation of quality improvement plans to maximize the efficiency of the Calibration Team.
  • Carry out all duties within the PBL and PHE and specific safety and Quality Policies.
  • Ensure adequate Calibration, Instrumentation and automation procedures and processes are in place to meet the business, GxP quality system and regulatory requirements.

Person Specification

  • Have current right to work in the UK;
  • Educated to degree level in a life/applied science subject or equivalent level qualification or significant experience of working at a similar level in delivery of calibration services.
  • Effective leadership and planning skills.
  • Extensive Practical, pharmaceutical industry experience of GMP facilities and equipment.
  • Experience of working within a GMP Quality System, in particular, change control, Non-Conformance management, CAPA, discrepancy/deviation, and documentation management.
  • Experience of dealing with internal customers, negotiating and agreeing work programmes, reporting progress, dealing with issues to ensure delivery and customer satisfaction.
  • Accurate and clear record keeping.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL637 Production Technician (Part Time/Full Time includes weekends)

Salary: £20,200.00 per annum, pro rata

Reference Number: PBL637

An exciting opportunity has arisen for a Production Technician to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Production Technician will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Seed Unit Support Team who are responsible for supporting the manufacturing operations of two facilities, carrying out cleaning, monitoring, sampling and stock control. As a Production Technician for Porton Biopharma, the post holder will work as part of a team to support manufacturing operations across a site with multiple manufacturing areas. This role can be taken as part-time or full-time but weekend work (Saturday and Sunday) is essential.

Key responsibilities

  • Specialist cleaning of the manufacturing areas and peripheries.
  • Assist with Environmental Monitoring of the FPP Main Process Hall and B20.
  • Assist with the water sampling of the FPP Main Process Hall and B20.
  • Assist with transporting product, materials, and equipment to and from the Main PHE site.
  • Assist with the ordering, stocking up, and maintenance of consumables.
  • Ensure compliance is maintained during manufacture and that PBL policies and procedures are applied when necessary.
  • Liaise with Pharmaceutical Stores, Quality Control and EMCOR to ensure the unit stays within compliance and is ready for operations when required.
  • Ensuring training is completed and up to date for their required area of work.

 

Person Specification

  • Have current right to work in the UK;
  • Hold or be able to achieve national security clearance to SC level
  • Have an interest in working in within a GMP manufacturing environment
  • Strong communication and written skills

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL638 Senior Production Technician (B20 Seed + shift)

Salary: Cira £20,200.00 per annum plus 30% shift allowance, dependant on experience

Reference Number: PBL638

An exciting opportunity has arisen for a Senior Production Technician to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Senior Production Technician will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Production Division in a shift working role which will attract a salary enhancement once appointed. This Senior Production Technician post is located at Porton Down in the B20 Fermentation Facility, which is a current Good Manufacturing Practice (cGMP) pharmaceutical manufacturing facility. This facility produces therapeutic products by bacterial fermentation. Therapeutic products produced at Porton are licensed and marketed for worldwide distribution.

Candidates should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. They should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

The successful candidate will work a shift pattern which covers 24-hour, 7 days working. They will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements. This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large-scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be provided.

Key responsibilities

  • To carry out duties involved in the manufacture of biopharmaceuticals to GMP and ISO 9001 requirements as directed.
  • Ensure that the facility is maintained in a compliant state and that the product/materials are manufactured to appropriate regulatory requirements.
  • To undertake all necessary training to enable the post holder to carry out their duties to a required standard.
  • To undertake work in accordance with PBL Health and Safety Policies and procedures and to work within any Quality systems that are appropriate to the site.
  • To comply with all PBL policies and procedures.
  • In line with any other responsibilities, to perform any other tasks assigned by the Line Manager.

 Person Specification

  • Have current right to work in the UK;
  • GCSEs in English, Maths and Science or equivalent qualifications.
  • A NVQ level 2 in a relevant subject or equivalent, or relevant experience.
  • Successful applicants must either hold or be capable of obtaining a UK government security clearance at SC level. To obtain clearance at this level you must have been resident in the UK for the last five years and not lived abroad for more than six months in the past twelve.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL639 Senior Production Technician (PPC 5-8)

Salary: Circa £20,200.00 per annum dependant on experience

Reference Number: PBL639

An exciting opportunity has arisen for a Senior Production Technician to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Senior Production Technician will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Production Support Unit, who are responsible the preparation, of equipment and reagents used during filling, freeze drying and finishing of pharmaceutical products. Working in a highly regulated environment, you will be working in a small team involved in the production of pharmaceutical products and the operation of production equipment used in the preparation of components. As a Senior Production Technician for Porton Biopharma, the post holder will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements. This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment to preparation, completion, and review of Quality documentation. Full training will be provided.

Key responsibilities

  • Be able to organise and perform, when applicable, activities relating to the cGMP manufacturing of pharmaceutical products, i.e. prepare media, buffers and reagents, both sterile and non-sterile.
  • Day to day tasks also include maintaining the facility via specialist cleaning procedures, monitoring environmental conditions and performing aseptic processes within a cleanroom environment.
  • Ensure that their daily activities are coordinated with other team members.
  • Work within a GMP quality system.
  • Ensure that documentation is completed within the legal frameworks.
  • Take responsibility for Non-Conformances, CAPA, Risk Assessments and Change Controls for the area and ensure SOPs and BMRs are available for use.

 Person Specification

  • Have current right to work in the UK;
  • GCSE’s in in Maths, English and Science or equivalent qualifications
  • A minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience
  • Worked within a manufacturing environment and with the Quality systems associated with cGMP manufacture.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL641 Senior Production Technician (Immuno 37.5 hrs pw)

Salary: £20,220 per annum

Reference Number: PBL641

An exciting opportunity has arisen for a Senior Production Technician to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Senior Production Technician will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Immuno Unit, who are responsible for the manufacture of the UK’s licenced anthrax vaccine. As a Senior Production Technician for Porton Biopharma, the post holder will work in aseptic cleanrooms, using high-grade isolators for bulk processing activities, as well as maintaining and monitoring the facility and critical GMP records. The post holder should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. They should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should be able to work effectively as part of a team, be proactive and able to work on their own initiative when required. The successful candidate will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements.

Key responsibilities

  • Perform a range of routine Production and some non-routine technical procedures and understand the rationale behind the procedures and practices.
  • Undertake all work in accordance with PBL’s Code of Safety Practice, Quality System and all other regulatory requirements.
  • Follow defined procedures, policies, rules, regulations and guidelines for all activities to ensure product meets the required standard.
  • Generate and review documentation with regard to Risk Assessments and cGMP to ensure compliance of the unit with all necessary regulations.
  • Work diligently at all times. Complete documentation and records accurately and to a high standard.
  • Ensure the unit is maintained in a compliant state. Work to cGMP following Standard Operating Procedures (SOPs) and Codes of Practice. Keep updated on new rules and regulations.
  • Maintain production areas to the required standard using defined cleaning procedures.
  • Perform and record environmental monitoring and water sampling in cGMP areas in accordance with documented procedures. Monitor and record air pressures and hot and cold facility temperatures.
  • Analyse information and make decisions based on assessment.
  • Assist validation department with validation protocols on equipment.
  • Maintain and use a variety of laboratory equipment.
  • Work with a range of hazardous and non-hazardous chemicals.
  • Be competent in and perform aseptic techniques.
  • Be qualified to work in a clean room environment and in containment level 3 suites.
  • Work accurately and with good hand eye co-ordination, sometimes for prolonged periods of time.
  • Operate autoclaves and sterilising ovens and have an appropriate level of understanding to review cycle data as a senior operator.

 Person Specification

  • Have current right to work in the UK;
  • GCSE (grades A – C) in Maths, English and Science or relevant experience
  • Worked within a manufacturing environment and with the Quality systems associated with cGMP manufacture.
  • Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL643 Senior Microbiologist (Compliance)

Salary: Circa £27,000 per annum, dependant on experience

Closing Date: 23rd April 2021

Reference Number: PBL643

An exciting opportunity has arisen for a Senior Microbiologist (Compliance) to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Senior Microbiologist (Compliance) will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the QC Microbiology department who are responsible for the Quality Control and Environmental Monitoring to support the manufacture of Erwinase and Anthrax Vaccine. The purpose of this role is to provide support for the QC Microbiology department at Porton Biopharma. This will include compilation of compliance documentation, including writing deviations, non-conformances and CAPA, change controls, protocols and reports. The holder will also to undertake and perform microbiological QC analyses in compliance with cGMP.

Key responsibilities

  • Operate in compliance in GMP and quality systems
  • Write and review Standard Operating Procedures, protocols and reports in accordance with regulatory requirements.
  • Investigate, write and review non-conformances and deviations raised in accordance with regulatory requirements.
  • Complete departmental CAPAs and to implement any required quality improvements that may arise from this.
  • Identify and implement quality improvements within the department pro-actively.
  • Carry out change management, raising, writing and reviewing change controls.
  • Assist as a member of the QC Microbiology Team, on a day to day basis.
  • Test microbiological samples, working at ACDP Containment level 2 and at Containment Level 3, when required, from all stages of the production processes of products manufactured at PBL, Porton Down and to assess the results against pre-set standards.
  • Record and assess results from environmental and water sampling and carry out preliminary and confirmatory identification of micro-organisms.

 Person Specification

  • Have current right to work in the UK;
  • We are looking for A candidate with significant experience of working to cGMP, with a significant knowledge of pharmaceutical Quality Assurance. The candidate must have experience in writing and reviewing discrepancies, procedures, change controls and CAPAs. The candidate should have a significant level of experience of working within ACDP containment level 2 microbiology laboratories.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL644 Process Validation Specialist

Salary: Circa £29335.00 per annum, dependant on experience

Closing Date: 23rd April 2021

Reference Number: PBL644

An exciting opportunity has arisen for a Process Validation Specialist to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The Process Validation Specialist will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Process Validation team within the Validation Department, who are responsible for the execution of Performance Qualification and Process Performance Qualification activities in support of PBL manufacturing activities and in accordance with Regulatory requirements.

As a Process Validation Specialist for Porton Biopharma, the post holder will be expected to attend project group meetings, liaise with PBL support teams, regulatory bodies and peers to establish data for inclusion in protocols and reports.

 

Key responsibilities

  • To coordinate the execution of the Validation Master Plan with respect to Process Validation activities.
  • Assess Change control documentation to determine change impact with respect to the validation requirements and report appropriately.
  • To support operational areas in the implementation of change.
  • Support Process Validation activities.
  • Define Process Validation Strategies in conjunction with the Process Validation Lead.
  • Author and review Process Validation plans, protocols and reports ensuring compliance to PBL policies and procedures.
  • Schedule and support Process Validation executions.
  • High level of technical and scientific writing required.
  • Understand and Applies statistical tools for development of protocols and data analysis for Process Validation (as per current FDA/MHRA Process validation lifecycle guidelines).
  • Present Process Validation documents at regulatory audits.
  • Performs process investigations with relevant departments as required.
  • Performs product and process impact assessments.
  • Participates in or Lead process and quality risk assessments
  • Presents findings at group and at interdepartmental meetings.
  • Communicate information on current process data which may impact Process Validation.
  • Maintain and review the Product Control Strategy for all products. Understand the functional relationships that link CMA/CPP to CQA.
  • To ensure the timely completion of Deviations and the closure of CAPAs.
  • Participate in Continued Process Verification Activities (CPV) including the generation of CPV plans and CPV reporting.

 Person Specification

  • Have current right to work in the UK;
  • Degree in Science or Engineering or equivalent and recognised academic achievement.
  • Understanding of the Validation Life Cycle.
  • Project Management experience.
  • Management of internal customer expectations.
  • Statistical package use.
  • Good computer skills: Word, Excel.
  • Validation experience ideally within a Biopharmaceutical environment.
  • Biotechnology experience.
  • Statistical evaluation of data.
  • Coordination of cross functional teams.

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here

PBL645 QC LIMS System Administrator & SME (Fixed Term 18 months)

Salary: Circa £29,355.00 DOE

Closing Date: 23rd April 2021

Reference Number: PBL645

An exciting opportunity has arisen for a QC LIMS System Administrator and SME (18 month FTC) to join Porton Biopharma, a leading biopharmaceuticals company located on the historic Porton Down site, in the picturesque countryside of Salisbury, Wiltshire.

Porton Biopharma Limited (PBL) is a limited liability company, established in 2015, to commercialise pharmaceutical development and manufacturing capabilities. Our mission is to protect patients’ health through the quality-assured development and production of biopharmaceuticals.  We develop new vaccines, therapeutic proteins and enzyme products, and manufacture our own licensed biopharmaceutical products, Erwinase® and the UK’s Anthrax Vaccine.

We offer specialist expertise in the development of both manufacturing and analytical processes for use with biological pharmaceutical products. Particularly in taking concepts from the research laboratory and progressing them through the various stages of scale-up and process development to manufactured product for licensed supply or clinical trial.

Our employees join us safe in the knowledge that their skills and experience are contributing to a valuable purpose. This is an excellent environment for the right person to build their biopharmaceutical career.

The QC LIMS System Administrator and SME will be in receipt of a competitive benefits package, including:

  • 30 days of holiday, plus 8 bank holidays;
  • On the job training, and genuine opportunities for growth and advancement;
  • Generous pension scheme;
  • Access to online discounts;
  • A work environment based in the beautiful Salisbury countryside, with free on-site parking; easy access to London and the south coast
  • Onsite canteen.
  • Onsite nursery

The successful candidate will be joining the Quality Control department, who are responsible for provision of quality control testing of Biopharmaceutical products, raw materials and water systems as well as running the environmental monitoring and stability programs. As a QC LIMS System Administrator and SME for Porton Biopharma, the post holder will play a key role in LIMS project team designing, validating and implementing LIMS. This role will operate as the interface between the project team and Quality Control and the position is crucial to ensuring efficient and compliant processes are introduced as part of the LIMS project.

Key responsibilities

  • Work with all appropriate stakeholder both internal and external to QC to develop efficient process working practices
  • Work with LIMS supplier to develop a system in line with use requirements
  • Use problem solving techniques to overcome problems between proposed working practices and feasible solutions. Introduce any corrective actions.
  • Assist with the validation of the LIMS system including writing the validation protocol, validation report and any discrepancies arising during the validation.
  • Review current SOPs and amend or write new SOPs as appropriate incorporating new and efficient ways of working.
  • Communicate and report on the progress of the LIMS project with staff, management and stakeholders as appropriate.
  • Work with the LIMS team to develop and roll out training in the LIMS system.
  • To assist with the development of system policies and procedures.
  • To co-ordinate with IT and vendor technical support to ensure timely resolution of issues.
  • To assist with the generation, tracking and trending of Quality metrics.
  • Gathering Static data for the configuration of LIMS and creation of data in the system
  • To undertake work in accordance with the PBL Health and Safety policies and procedures and to work within any Quality Systems that are applicable to the site.
  • To comply with all PBL policies and procedures.

 Person Specification

  • Have current right to work in the UK;
  • Degree in Science or Engineering or equivalent and recognised academic achievement.
  • At least 5 years validation experience ideally within a Biopharma environment.
  • Experience and knowledge of statistical evaluation of data.
  • Understanding of Validation Life Cycle
  • Experience and understanding using a LIMS system and knowledge of best practices and efficient ways of working.
  • Coordination of cross functional teams
  • Project management

For this unique opportunity to join our team and develop your biopharmaceutical career experience, please submit your CV and a covering letter. You should outline the skills and experience you have, which are relevant to the post for which you are applying. For more guidance on role requirements, please visit our website, portonbiopharma.com/careers, to download the Job Description.

PBL is an equal opportunities employer, celebrating and encouraging diversity of applications.

Porton Biopharma Ltd is committed to the fair and transparent processing of applicant data. To enable the Company to assess suitability for advertised roles, we will collect the following data: name and contact details, previous work experience and history, qualifications, education, right to work in the UK eligibility, present salary and equal opportunities. The Company reserves the right to collect this data under article 6(1)(B) of the GDPR.

Applicants applying for this role will have their data collected and held securely, and confidentially within Company IT systems which are compliant with GDPR. Data will be shared with the HR department, recruiting managers and recruiting panel.

The Company will hold applicant data on file for 12-months post the vacancy being successfully filled. Candidates are welcome to request that their personal data is removed prior to this date, and should contact recruitment@portonbiopharma.com if they wish to exercise this right. The Company complies with all data subject rights as outlined on the ICO Website. For more information, please refer to our privacy notice: https://www.portonbiopharma.com/privacy-policy/.

To download the job description please click here