Careers

Porton Biopharma has approximately 350 staff in a wide range of roles from those working in our pharmaceutical manufacturing plants, through to our quality and scientific development groups.  All focused on developing & manufacturing life-saving products that make a real difference to patients’ lives.

We are always looking for people, ranging from those with a general interest in science & technology, to ones with higher qualifications and/or experience.

This currently includes various vacancies for pharmaceutical production staff and supervisors to support our continued growth.  So if you are a motivated person who is interested in working in a high-tech environment as part of a dynamic team, then there could be a role for you.

 

 

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WE OFFER…

A friendly environment working alongside committed teams of people, who will be happy to share their knowledge and experience to allow you to develop your potential, with benefits that include:

  • a competitive salary
  • the necessary training
  • a pension scheme
  • 30 days annual leave
  • a canteen, gym and an active sports & social club
  • free on-site parking

With ongoing investment into the company and plans to increase our workforce, we are committed to being a leading life-science company that really makes a difference to patients’ lives.

To see the sort of  people that we ‘re looking for, the  Staff Profiles page has short interviews with current staff giving an overview of just some of our roles.

CURRENT VACANCIES…

PBL only accept CV’s from Recruitment Agencies with whom we have agreed Terms & Conditions.

A list of our current vacancies shown below.

To apply for a specific vacancy applicants should  send a covering letter quoting the Job Reference Number, a copy of their CV, together with a supporting statement referring to both the Job Description and Person Specification.

However, we also welcome applications from people with transferable skills that are looking for that next challenge and to develop their career.  To be considered for up-and-coming roles please send a covering letter indicating why you want to join PBL and in which area your career aspirations lie (Engineering  / Production  / Quality etc.),  along with a CV detailing your skills and experience which we can keep on file for when a suitable position becomes available.

All applications should be sent to recruitment@portonbiopharma.com.

WORK EXPERIENCE

As a business, we recognise the value that offering work-experience placements can bring and typically offer up to 4  one-week placements each year, usually in June.   All applicants must be over 16 years of age at the time of the placement, and will be chosen following a selection process.

If you are interested in applying, then send an email and covering letter stating your interest and giving reasons why we should choose you to business@portonbiopharma.com  Applications must be received by the end of November in order to be considered for the following summer’s places.

 

PBL465 QC Microbiology Manager

Salary: Circa £50,000 per annum

Reference Number: PBL465

Job Purpose…

The successful candidate will lead the Microbiology Department to successfully deliver quality products on time in full. This role will provide Line Management for 4 area managers supervising established teams within the Microbiology Department. The overall team equates to approximately 30 quality professionals.

The post holder will…

  • Work with other managers within the Quality team to ensure that manufacturing and quality activities are performed in compliance with all the regulations and other requirements including: The Rules & Guidance for Pharmaceutical Manufacturers' and Distributors, cGMP guidance, and other regulations governing PBL activities.
  • Lead projects and deliver required outcomes in their own specialist area.
  • Lead, motivate, coach, mentor and manage the performance and output of the Microbiology Team (including direct managerial reports) and ensure that all team objectives are met in agreed timescales.
  • Maintain and develop the local standard operating procedures to secure effective working practices as well as compliance with relevant national, European and US legislation.
  • Monitor the performance of the systems under area of responsibility using KPIs and report to management.
  • Develop and implement an ongoing Quality Improvement Plan related to the systems under area of responsibility
  • Lead the development and implementation of an ongoing Health & Safety Plan for the team to secure the right level of performance, highlight failures and make recommendations for solutions.
  • In line with overall responsibilities, perform additional tasks assigned by the line manager.

We are looking for…

A highly motivated quality professional with drive and passion to inspire and deliver through the team reporting to them. They will be educated to degree level or equivalent in an appropriate scientific discipline and a post-graduate degree in life/applied science or equivalent would be desirable. The successful applicant will be a strong manager with an up to date microbiology background and proven experience in the pharma industry. The post holder will be customer focused, deliver continuous improvement activities and be a subject matter expert for microbiological issues encountered during the manufacturing and testing of PBL licensed products. Previous experience of managing laboratory staff and associated activities is essential.

The successful applicant should be prepared to participate in out of hours on call Rota if required and be prepared to meet the requirements of manufacturing schedules which may include working out of hours or weekends.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL491 Visual Inspection Production Technician

Salary: Circa £19,086 negotiable dependent upon experience

Reference Number: PBL491

Job Purpose…

This post is part of the Product Finishing team within PBL’s Pharmaceutical Production Unit which is responsible for duties including media and equipment preparation, assisting with purification and formulation of Erwinase Drug Substance, sterile filtration, and aseptic processing within a Good Manufacturing Process (GMP) department.

This post will involve training and qualification in the visual inspection process. Once qualified, the post will involve manual visual inspection of all Erwinase vials as part of the product finishing process. Other visual inspection processes will also be undertaken such as media simulation and lactose fills when required. The main responsibility of the role is within the visual inspection team however when time permits there will be opportunities to engage in other aspects within the production unit. The post holder will report to the Product Finishing Team Leader/supervisor.

The post holder will…

The visual inspection team performs the manual 100% visual inspection of Erwinase vials, a process which involves a visual assessment of final drug product vials and the removal of rejected material from the batch. Full training will be provided and once qualified you will work together as part of the team to undertake the visual inspection of all Erwinase batches manufactured. This activity will take up the majority of the time however there are opportunities between inspections to work alongside other production operators and become trained in other processes within the Production unit.

We are looking for…

The post holder will have a good general education and be educated to a minimum of NVQ 2 level in a relevant subject or equivalent level of qualification or significant equivalent proven experience as well as holding a GCSE in Mathematics, English & Science. The nature of this post requires individuals who can remain diligent and focused throughout the day. Candidates will have experience of working to deadlines, schedules and the ability to follow written procedures. Candidates need to have excellent attention to detail, be a good communicator and be able to work effectively as part of a team.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL416 Mechanical Maintenance Technician

Salary: Circa £32,000 + 20% shift allowance

Closing Date: 31st May 2019

Reference Number: PBL416

Job Summary…

As Mechanical Maintenance Technician you will perform planned and reactive activities to maintain optimum life and operation of machinery, equipment and utilities across the fermentation process at PBL. This role involves interfacing with equipment/system owners, the principle maintenance contractor, capital project managers and the Quality Departments to ensure compliance is maintained with current Good Manufacturing Practice. You will be required to be part of an existing maintenance shift pattern covering the periods of 06.00 – 14.00, 08.00 - 17.00 or 14.00 – 22.00 and be placed on a callout rota to support the out of hours shift engineers.

The post holder will…

Working within the GMP Engineering team you will undertake all aspects of both planned and reactive maintenance on process fermentation vessels, centrifuges, CIP skids, autoclaves and the Effluent treatment plant along with the site utilities of clean steam, plant steam and purified water. The tasks will be varied from full annual servicing to routine daily checks of PBL equipment and utilities.

With support you will be ensuring all PBL equipment and utilities are maintained at all times. You will become a valued member of the GMP engineering team working to minimize disruption to manufacturing activities.

We are looking for…

A candidate who is educated to NVQ level in relevant subject or equivalent level qualification via a mechanical based apprenticeship. The successful candidate will need to have previous experience of working in a production driven environment within a highly regulated industry; experience of working within Quality Systems would be advantageous. It is an essential requirement of the role that the post holder have knowledge of Engineering Health & Safety Legislation and its application to maintenance operations. The post holder will have good organisational skills and have a proven ability for fault investigation. They will have good communication skills with the ability to follow written procedures and be able to build effective working relationships both internally and externally of the business and be proactive and able to work on their own initiative.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL415 Electrical Controls & Instrumentation Technician

Salary: Circa £32,000 per annum + shift allowance

Closing Date: 31st May 2019

Reference Number: PBL415

Job Summary…

As Electrical Controls and Instrumentation Technician, you will perform all Electrical and Instrumentation activities to maintain optimum life and operation of machinery, equipment and utilities across the fermentation process at PBL. This role involves interfacing with equipment/system owners, the principle maintenance contractor, capital project managers and the Quality Departments to ensure compliance is maintained with current Good Manufacturing Practice. You will be required to be part of an existing maintenance shift pattern covering the periods of 06.00 – 14.00, 08.00-17.00 or 14.00 – 22.00 and be placed on a callout rota to support the out of hours shift engineers.

The Post Holder will…

Working within the GMP Engineering team you will undertake all aspects of both planned and reactive maintenance on process fermentation vessels, centrifuges, CIP skids and the Effluent treatment plant along with the site utilities of clean steam, plant steam and purified water. The tasks will be varied from full annual servicing to routine daily checks of PBL equipment and utilities

With support you will be ensuring all PBL equipment and utilities are maintained at all times. You will become a valued member of the GMP engineering team working to minimize disruption to manufacturing activities.

We are looking for…

A candidate who holds a City & Guilds 18th Edition Electrical or equivalent qualification and an Industry recognised qualification in Controls & Instrumentation. The successful candidate will need to have previous experience with Electrical Controls and Instrumentation within a regulated environment and experience of working within Quality Systems would be advantageous. It is an essential requirement of the role that the post holder have knowledge of Engineering Health & safety Legislation and its application to maintenance operations. The post holder will have good organisational skills and have a proven ability for fault investigation. They will have good communication skills with the ability to follow written procedures and be able to build effective working relationships both internally and externally of the business and be proactive and able to work on their own initiative.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL493 Production Office Supervisor

Salary: Starting salary £22,660 negotiable dependent upon experience

Reference Number: PBL493

Job Purpose…

The Production Office Supervisor will manage a small team based at the Fermentation Process Plant. They will be responsible for all GMP documentation, electronic systems and stock control for three manufacturing areas.

We are looking for…

An individual educated to NVQ Level 2 or equivalent qualification or with at least 2 year’s relevant experience in a GMP facility. The candidate should have strong interpersonal skills and have previous management or supervisory experience.

The post holder will…

  • Manage a small team, carrying out monthly 1:1 reviews, annual appraisals, and daily tasks
  • Collect, prepare and review all GMP documents used during activities
  • Administrate of electronic systems
  • Order, receive and manage temperature controlled and general stock used in the manufacturing facilities
  • Ensure all staff are suitably trained to enable them to carry out their duties in a compliant manner
  • Undertake work in accordance with PBL Health and Safety policies and maintain compliance within site wide Quality systems as appropriate
  • Perform any other tasks as required by the role or the Unit Manager

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL487 QC Laboratory Technician

Salary: Starting salary £17,572 negotiable dependent upon experience.

Reference Number: PBL487

Job Purpose…

To support the Quality Control Bacteriology Technical Services Unit, which performs specialist microbiological testing services to assist licensed pharmaceutical manufacture in compliance with cGMP.

We are looking for…

An applicant who is educated to NVQ Level 3 or equivalent in a numerical or science-based subject or has significant experience in a similar role. The successful candidate will have an interest in science and working in a laboratory, have good attention to detail and be highly organised. We are looking for someone who has good communication skills and enjoys working as part of a team.

The post holder will…

  • Ensure the environment in departmental laboratories is maintained to GMP standards of cleanliness, tidiness and audit preparedness.
  • Be responsible for cleaning and monitoring of equipment in the department.
  • Decontaminate and dispose of laboratory waste.
  • Preparation of equipment for calibration, validation, servicing and maintenance.
  • Housekeeping duties to ensure the smooth running of the department.
  • Maintaining stock inventories and monitor stock levels.
  • Support QC Technologists in their role in the testing of production samples.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL486 Environmental Monitoring Compliance Officer

Salary: Circa £28,000 - £30,000 per annum

Reference Number: PBL486

Job Purpose…

The purpose of this role is to provide support for the Sterility Assurance Program at Porton Biopharma. This will include compilation of environmental monitoring trend reports, managing GMP databases and preparing technical reports. The applicant will be taking a leading role in SOP review, developing sampling programs, leading investigations and providing technical support as required.

We are looking for…

A candidate who is educated to degree level or equivalent in microbiology, chemistry or pharmaceuticals who has GMP experience of working in cleanrooms, developing environmental monitoring programs through a risk-based approach and giving technical support in investigations. The candidate should have a good understanding of QC Microbiology laboratory testing, EM and Water testing, working with computer databases and be competent in programs such as MS Excel.  Applicants must have a flexible approach to working and be able to comply with SAPO regulations.

The post holder will…

  • Manage the GMP databases for water quality, clean steam quality and microbiological environmental monitoring.
  • Co-ordinate and review water quality, clean steam quality and microbiological environmental monitoring activities as required.
  • Prepare and analyse technical and numerical information from the databases and prepare trend analysis data as graphs, charts and or diagrams.
  • Investigate OOS water and environmental monitoring test results and review resulting Non-Conformances.
  • Prepare environmental summary reports of production batches and process simulations for inclusion in the batch manufacturing records.
  • Review particle monitoring data from the manufacturing areas.
  • Review and manage the environmental monitoring SOPs.
  • Liaise with production, quality and engineering services to promote GMP compliance. Review facility, utility and equipment documentation and monitoring data to prepare facility release reports.
  • Carry out facility release and other internal and external audits

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

To download the job description please click here

PBL485 QC Technologist (Monitoring and Training)

Salary: Circa £23,000 per annum

Reference Number: PBL485

Job Purpose…

To provide specialist training in microbiological environmental monitoring methods, cleanroom gowning, aseptic practices and water sampling. The successful candidate will also be required to undertake microbiological environmental monitoring of critical pharmaceutical manufacturing operations to support the Sterility Assurance Program. To supervise, oversee, observe and qualify all production technologists and other staff where applicable, in gowning, microbiological environmental monitoring methods and water sampling.

We are looking for…

A candidate who has previous experience of working in cleanrooms, performing environmental monitoring and training of other members of staff to join the Environmental Monitoring Team within QC Biological Services. A degree in a relevant scientific discipline is desirable but not essential. The candidate should also have a good understanding of QC Microbiology laboratory testing. Applicants must have a flexible approach to working and be able to comply with SAPO regulations and must have a current valid right to work in the UK.

The post holder will…

  • Operate in compliance with cGMP.
  • Train and qualify all Production and other staff, as necessary, in the techniques and procedures for microbiological environmental monitoring.
  • Train and qualify all Production and other staff, as necessary, in water sampling.
  • Train and qualify all Production and other staff, as necessary, in procedures for gowning.
  • Oversee, supervise and observe Production and other staff undertaking environmental monitoring and water sampling to ensure continued compliance.
  • Re-qualify Production and other staff at a defined frequency, as required by GMP.
  • Plan and organise schedules for training, qualifications and observations.
  • Assess staff competence in environmental monitoring, water sampling and gowning procedures. Sign training documentation and produce certificates for trained members of staff.
  • Carry out and record microbiological environmental monitoring for critical manufacturing operations, and routine monitoring where required.
  • Input microbiological environmental monitoring and water sampling data into appropriate databases and spreadsheets.
  • Be involved in the writing and updating of Standard Operating Procedures relating to environmental monitoring and water sampling, either as the author, or by providing technical information and advice to the author.
  • Attend training courses that contribute to the efficiency of the operating systems and are beneficial to the post holder’s personal development.
  • Follow operating procedures at all times and ask for advice when necessary.
  • Undertake all work in accordance with Porton Down’s Code of Safety Practice and Quality Systems.
  • To prepare environmental summary reports of production processes for insertion into documents, reports and batch manufacturing records as part of batch release.
  • To investigate out-of-specification water and environmental monitoring test results in conjunction with the Compliance Team and review resulting Non-Conformances, participating in Ishikawa and 5-Whys investigations, where necessary.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

To download the job description please click here

PBL484 Payroll Administrator - Part Time 20 hours per week - 12 Month FTC

Salary: Circa £22,000 per annum pro rata

Closing Date: 3rd June 2019

Reference Number: PBL484

Job Purpose...

Porton Biopharma Ltd has recently in-sourced responsibility for payroll services and moved provision of payroll services from Public Health England to an external third-party payroll bureau. The position of Payroll Administrator is a newly created role following the migration of the payroll.

The role of Payroll Administrator is to administer the payroll for approximately 350 staff. The Payroll Administrator will be responsible for ensuring the smooth running of a timely and accurate monthly payroll for the employees of Porton Biopharma Ltd. The role will entail updating the payroll data for all monthly changes to the payroll i.e. leavers, starters, overtime, SSP/SMP etc and checking the payroll file once it has been returned from the payroll provider to ensure that the data is correct prior to payment of the monthly salaries.

We are looking for…

An individual who is pro-active, has a flexible approach and is a team player. The successful candidate will have a minimum of 2 years payroll experience, will have good time management skills, be computer literate with strong excel skills, be able to work to strict deadlines and will have the ability to communicate effectively and professionally within the company.

 The post holder will…

  1. Input updates to the monthly payroll e.g.:
    • Leavers/starters
    • Overtime
    • Shift allowance
    • SSP/SMP
    • Pensions and other deductions
  2. Check the payroll file for accuracy prior to payment of the monthly salaries
  3. Liaise with staff to resolve any payroll queries
  4. Ensure correct payments are made to HMRC, pensions etc.
  5. Liaise closely with the payroll bureau
  6. Year-end payroll processes
  7. Ad-hoc duties as required.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right close this vacancy early if a suitable applicant is found.

To download the job description please click here

PBL411 Aseptic Processing Specialist

Salary: Starting salary £29,355 negotiable dependent upon experience

Reference Number: PBL411

Job Purpose…

This position will report to the Aseptic Processing Functional Manager and will provide technical specialist support to all aseptic processing activities in the manufacture of Erwinase, Anthrax vaccine and other PBL products. The role will work cross functionally and be involved in current projects, new projects and all manufacturing activities that require aseptic processing input. It is expected that the role will typically focus on day to day aseptic processing matters within Production but may also be required to support projects designed to improve and develop PBL’s aseptic processing strategy.

We are looking for…

An individual who is educated to degree level or equivalent in a relevant discipline. The successful candidate should have a minimum of 5 years’ experience within Biopharma / Pharma aseptic GMP environments and have an in depth understanding of aseptic processing and techniques. You will need to have an understanding of regulatory requirements for biological products and experience in the implementation of new technologies and equipment into GMP manufacture and will have proven experience of generating GMP documents within a quality system. Experience of delivering specialised technical training and report writing and data trending evaluation would be desirable but not essential. The successful applicant will have a flexible approach to work and be able to deliver to schedules.

The post holder will…

  • Lead in the day to day aseptic processing of PPL’s products.
  • Support the management and development of improved and new processing techniques in the various aseptic processing activities.
  • Provide technical support to production staff involved in the various aseptic processes.
  • Provide troubleshooting and technical support into process investigations.
  • Collate and share technical information with internal and external bodies to benefit the production methods, teams and departments.
  • Perform process mapping and process efficiency trending.
  • Provide specialist training to staff in aseptic processing techniques and theory.
  • Identify, evaluate and adapt new technologies where appropriate and ensure that the production area operates to a high standard and complies with GMP and other regulatory standards.
  • Assist colleagues in providing technical specialist input as required, in developing production and technical strategies for the units, identifying new opportunities as they arise and responding to external queries and complaints.
  • Contribute to reports and assist on the preparation of presentations, publications and liaison with customers, collaborators and licensing agencies.
  • Support the Functional Manager Aseptic Processing in pursuance of strategic improvements to aseptic processing control.

 

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL482 Senior Production Technician

Salary: Circa £19,086 per annum

Reference Number: PBL482

Job Purpose…

This post is part of a team located within the Pharmaceutical Production Centre (PPC) which is responsible for the production of pharmaceutical products, preparation of components and the operation of production equipment. Day to day tasks include maintaining the facility via specialist cleaning procedures and monitoring environmental conditions within a cleanroom environment. Other duties also include media and equipment preparation, assisting with purification and formulation of Erwinase®, sterile filtration and aseptic processing.

We are looking for…

An applicant who has a GCSE in Maths, English and Science or equivalent qualification. In addition, applicants should be educated to a minimum of NVQ Level 2 in a relevant subject or have proven significant equivalent experience. Candidates should have an interest in working within a manufacturing environment and the quality systems associated with cGMP manufacture. The successful applicant will have good communication, writing and data entry skills and will need to have a flexible approach to work. Candidates will need to be pro-active and able to work on their own initiative and be able to work effectively as part of a team.

The post holder will…

Report to the Production Supervisors and Unit Leader to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements. This role will involve undertaking a varied range of tasks from preparation and use of operational equipment to completion of Quality documentation, full training will be provided where required.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL483 Unit Supervisor - Production

Salary: Starting salary £22,660 negotiable dependent upon experience

Reference Number: PBL483

Job Purpose…

This post is located within the integrated filling line section of the Product Finishing Unit (PFU). PFU is a GMP manufacturing facility focused on the filling, freeze drying and visual inspection of pharmaceutical products. Working in a highly regulated environment, you’ll be supervising a small team operating production equipment to manufacture pharmaceutical products.

We are looking for…

Applicants should be educated to an HNC level (or equivalent) or have a minimum of two years significant equivalent GMP production experience. They should have significant experience in a relevant technical area and a good working knowledge of cGMP requirements and know how to implement them in the workplace. Applicants should be able to communicate clearly and possess good writing and data entry skills. Applicants should have well-developed problem-solving skills and the ability to respond to sudden unexpected demands. Lastly applicants should have a flexible approach to work, be able to work effectively as part of a team and be proactive and able to work on their own initiative when required.

The post holder will…

Report directly to the Unit Manager/Team Leader and will manage and supervise the output of a small team and equipment operation. You will be responsible for ensuring that the facility is maintained in a compliant state and that the product/materials are manufactured to appropriate regulatory requirements. Ensure that their daily activities are communicated to and coordinated with other team members. Working within a GMP Quality system, the post holder will be expected to take responsibility for non-conformances, CAPA, Risk Assessments and Change Controls for the area and ensure SOPs and BMRs are available for use.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

To download the job description please click here

PBL368 Production Technician

Salary: Starting salary £17,572 negotiable dependent upon experience + 10% shift allowance

Reference Number: PBL368

Porton Biopharma, Porton Down has approximately 350 staff, performing a range of process and analytical development, production, quality control and quality assurance roles associated with the development and manufacture of biopharmaceuticals.

This role can be taken as a part-time or full-time position; however this must include Saturday and Sunday working which attracts a 10% shift allowance.

Job Purpose / Summary

The successful candidate will assist the FPP Support Team with the routine tasks that are performed within the process hall including cleaning, environmental monitoring, water sampling, calibration checks, ordering and maintaining supplies of consumables. Some driving will be required to ensure delivery of samples and good communication with other members of staff.

We are looking for…

The successful applicant will preferably have prior experience of working within a GMP environments and have an interest in microbiology and the enthusiasm to pursue a career working in pharmaceuticals. You will have the ability to keep clear and accurate records and to follow written procedures as well as having excellent communication skills with a flexible approach to work.

The post holder will …

  • Function as part of the team responsible for cleaning of the FPP Main Process Hall, Seed Production Unit and periphery.
  • Assist with Environmental Monitoring of the FPP Main Process Hall.
  • Assist with the water sampling of the FPP Main Process Hall.
  • Assist with transporting product, materials, and equipment to and from the Main PHE site.
  • Assist with the ordering, stocking up, and maintenance of consumables.
  • Ensure compliance is maintained during manufacture and that PBL policies and procedures are applied when necessary.
  • Liaise with Pharmaceutical Stores, Quality Control and EMCOR to ensure the unit stays within compliance and is ready for operations when required.
  • Ensuring training is completed and up to date for their required area of work.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL448 Computer Systems Validation Manager

Salary: Circa £55,000

Reference Number: PBL448

Porton Biopharma, Porton Down has approximately 350 staff, performing a range of process and analytical development, production, quality control and quality assurance roles associated with the development and manufacture of biopharmaceuticals.

The Company carries out the manufacture of Erwinase and Anthrax Vaccine, as well as contract manufacturing projects.

Job Purpose…

The Facilities Validation department supports cGMP manufacturing activities and is responsible for ensuring compliance to the cGMP guidelines.

This role reports into the Validation Programme Manager and is responsible for the Computer Systems validation activities at Porton Biopharmaceuticals. The purpose of the role is to;

  • Lead and manage the compliance status and validation activities of computerised systems and associated equipment in accordance with current regulatory requirements.
  • Minimize business risk associated with the processing and storage of electronic documentation ensuring continuity over the equipment and product’s life cycle.
  • Develop a validation strategy vision and strategic plan which delivers compliant systems that are cost effective with long term sustainable components.
  • Develop individual validation strategies for large complex high value computer systems.
  • Lead, motivate and manage a team of Validation Specialists responsible for the validation of computerized systems and general equipment to deliver validation projects on time and in line with regulatory requirements.
  • Be the site management Leader on Computer System Validation activities communicating regulatory issues and business risks to senior management together with recommended actions.
  • Be an industry expert on Computer System Validation strategy.
  • Develop and manage KPIs for CSV and to manage the scheduling of all validation activities within the business.

We are looking for…

Someone with a degree in a scientific subject or equivalent with at least 5 years’ experience of Computerised Systems Validation knowledge. An understanding of data integrity and CFR 21 part 11 assessment experience is essential. The successful candidate should have experience of validation of Biopharmaceutical computer systems and be an experienced people Manager. Ideally the post holder will be experienced in being the Subject Matter Expert in regulatory inspections.

For further information about the post, please contact:

recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL 443 Process Development Scientist -3 Year Fixed Term Contract

Salary: Starting Salary £22,660 negotiable dependent upon experience.

Closing Date: 29th March 2019

Reference Number: PBL 443

Job Purpose / Summary

The Development Group plays a key role in the translational research activities of the site. The post-holder will provide scientific and technical assistance in the area of Downstream Processing to projects involved in the development of processes for the manufacture of biopharmaceutical products.

We are looking for…

Applicants should hold a science degree in biological science or biochemistry. They should have a demonstrable interest in Downstream processing techniques, development and scale up, previous experience is desirable but not essential.

Equally important requirements are a conscientious approach to work, precise attention to detail, ability to work independently and good communication skills. The post-holder will be part of a small flexible team reporting to the Development Scale up Lead.

The post holder will…

Provide scientific and technical assistance in the area of Downstream Processing to projects involved in the development of processes for the manufacture of biopharmaceutical products. Tasks will include the operation of protein purification equipment at various scales utilizing a variety of separation techniques. The post holder will have a keen interest in the area of protein purification, process development, scale up and validation. They will be required to work in multi-disciplinary teams and contribute to the generation of experimental designs, presentation of work to internal and external customers and the preparation of technical reports and project proposals. The post holder will contribute to process validation and manufacture problem solving activities and will play a supporting role in the technology transfer activities relating to the development and/or manufacture of biopharmaceutical products internally or between Porton Biopharma and its collaborators/customers.

For further information about the post, please contact: recruitment@portonbiopharma.com

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL 442 Computer Systems Validation Specialist

Salary: Starting salary £42,230 negotiable dependent upon experience.

Reference Number: PBL442

Job Purpose / Summary

The Facilities Validation department supports cGMP manufacturing activities and is responsible for ensuring compliance to the cGMP guidelines.This role reports into the Computer Systems Validation manager and is responsible for the timely execution of Computer Systems validation activities with respect to:

  1. Writing (and reviewing) of validation protocols
  2. Timely execution of CSV protocols with the subsequent generation of reports
  3. Leading CSV compliance investigations with respect to Non-conformances and CAPAs
  4. Performing CSV / Data integrity gap analysis and remediation activities.

The post holder will be expected to write, review and approve validation protocols, execute validation studies and write, approve validation reports associated with the qualification of Computerised systems and the introduction of new equipment into beneficial use.

We are looking for…

The successful candidate should be educated to BTEC National Certificate level or equivalent including science and a BSc in Engineering, Science or IT would be desirable. They will have substantial experience of generation, execution and review of validation protocols, reports and technical documents as well as experience of validation life-cycle activities for computerised systems. The successful applicant will have extensive practical experience of working within a GMP quality system. Practical experience of working within a biopharmaceutical manufacturing environment would be desirable.

This is a hands-on role in a dynamic operating environment and the ideal candidate should be self-driven and capable of organising their own work-load. They should be comfortable liaising with stake-holders in order to deliver an effective documentation to an agreed time line and be confident to supervise junior staff.

The post holder will…

  1. Take the lead in computer system validation and compliance, manage and deliver specific Validation Projects according to the business priorities, including work scheduling and supervision of junior members of staff.
  2. Promote continuous improvement of validation systems and procedures to ensure efficiency and best practice within the industry and to stay abreast of changing regulatory expectations.
  3. Write, review and approve validation documentation including protocols and reports and manage the timely closure of any discrepancies or non-conformities
  4. Provide a reliable service to our internal customers to ensure that timescales are met and work is carried out to meet expectations.
  5. Maintain the ongoing compliant status of computer systems associated with equipment, facilities and utilities by involvement of the scheduling of activities.
  6. Communicate validation activities with our internal and external customers and work with them to resolve problems and conflicts.
  7. In line with overall responsibilities, perform additional tasks assigned by the line manager.
  8. Undertake all work in accordance with Code of Safety Practice and site Quality Policies.

For further information about the post, please contact:

recruitment@portonbiopharma.com

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL459 Senior Production Technician

Salary: Starting Salary £17,572 negotiable dependent upon experience.

Reference Number: PBL459

Job Purpose / Summary

This is a shift working role which will attract a salary enhancement once appointed. This Senior Production Technician post is located at Porton Down in the Fermentation Process Plant (FPP) current Good Manufacturing Practice (cGMP) pharmaceutical manufacturing facility. This facility produces therapeutic products by bacterial fermentation followed by initial phase downstream processing.

Therapeutic products produced at Porton are licensed and marketed for worldwide distribution. The FPP is undergoing significant investment and expansion as production is being increased to meet product demand.

We are looking for…

An applicant who has GCSE’s in Maths, English and Science or equivalent qualifications. In addition, they should also be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. Candidates should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. They should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

The post holder will…

Work a shift pattern which covers 24-hour, 7 day working. They will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be provided.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information about the post, please contact:

recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL 461 Quality Assurance Compliance Officer

Salary: Starting salary £29,355 negotiable dependent upon experience

Reference Number: PBL 461

Job Purpose…

The successful applicant would be working within a multi-functional/ multi-disciplinary team, being the first QA point of contact for issues and resolution for quality matters. This role will be situated within departments across the business and will allow you to demonstrate your problem-solving skills as well as your ability to respond and adapt to various situations using risk management.

We are looking for…

An individual who is educated to at least degree level in a relevant subject (microbiology/ biotechnology) or equivalent qualification/ experience. They will have significant experience in Pharmaceutical Quality Assurance, as well as practical experience in:

  • Change Management
  • Risk Management
  • Non-Conformance
  • Batch Release
  • QA oversight across business

The post holder will…

Have excellent communication skills as well as being able to assess situations and take appropriate action. They will have resilience and determination to succeed in delivering work within strict timescales to ensure delivery of the product to patients. The post holder will need to be able to work weekends on occasion to support the needs of the business.

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close the role early if a suitable applicant is found.

To download the job description please click here

Flexible Working opportunities

Salary: dependant

Reference Number: PBL flexi

We are offering part-time opportunities to people who can contribute to the manufacturing of our life-saving products by providing general cleaning and support activities in our pharmaceutical production facilities, on a part-time basis.

We are looking to put together a team  and are considering what we can offer as an employer, so if you would like to contribute to our success and believe that you could play your part then we would like to hear from you.  Please send us a covering letter providing details of your typical availability and g quoting refrence PBL flexi.

PBL 223 Production Technician

Salary: Starting salary £17,572 negotiable dependent upon experience

Reference Number: PBL223

We are looking for...

Applicants should have GCSE in Maths, English and Science. In addition, candidates should be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. They should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. Candidates should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should have a flexible approach to work, be able to work effectively as part of a team, and be proactive and able to work on their own initiative when required.


The post holder will...

Assist with the varied support tasks that are performed within the FPP process hall. These tasks include environmental monitoring, water sampling, calibration checks, cleaning, laundry processing and dispatch, and ordering and maintaining supplies of consumables. Accurate completion of Quality documents will be required. Driving will also be required to ensure compliant delivery of production samples to the PBL main site. Lastly the post holder will require good communication skills to interact concisely with management, peers and junior members of staff.

He/she will support the Team Leader to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements

Successful applicants must either hold, or be capable of obtaining a UK government security clearance at SC level. To obtain clearance at this level you must have been resident in the UK for the last five years, and not have lived abroad for more than six months out of the last twelve.

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

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PBL 435 Senior Production Technician

Salary: Starting Salary £17,572 negotiable dependent upon experience

Reference Number: PBL 435

Job Summary...

Working as part of a team involved in the fermentation and recovery operations of the Erwinase manufacturing process, working within cGMP/ISO 9001 Quality Systems.

We are looking for…

Applicants who are educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. They will also need to have GCSE's Grade C or above in Maths, English and Science. They should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. Candidates should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should have a flexible approach to work, be able to work effectively as part of a team, and be proactive and able to work on their own initiative when required.

The post holder will…

Report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be given where required.

  • Carry out duties involved in the manufacture of biopharmaceuticals to GMP and ISO 9001 requirements as directed.
  • Ensure that the facility is maintained in a compliant state and that the product/materials are manufactured to appropriate regulatory requirements.
  • Undertake all necessary training to enable the post holder to carry out his/her duties to the required standard.
  • Undertake work in accordance with PBL Health and Safety Policies and procedures and to work within any Quality systems that are appropriate to the site.
  • Comply with all PBL policies and procedures.
  • Perform any other tasks assigned by the Line Manager.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information about the post, please contact:

recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

 

To download the job description please click here

PBL 432 Senior Production Technician

Salary: Starting salary £17,572 negotiable dependent upon experience

Reference Number: PBL 432

Job Summary...

Working as part of a team involved in the fermentation and recovery operations of the Erwinase manufacturing process, working within cGMP/ISO 9001 Quality Systems.

We are looking for…

Applicants who are educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. They will also need to have GCSE's Grade C or above in Maths, English and Science. They should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. Candidates should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should have a flexible approach to work, be able to work effectively as part of a team, and be proactive and able to work on their own initiative when required.

The post holder will…

Report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be given where required.

  • Carry out duties involved in the manufacture of biopharmaceuticals to GMP and ISO 9001 requirements as directed.
  • Ensure that the facility is maintained in a compliant state and that the product/materials are manufactured to appropriate regulatory requirements.
  • Undertake all necessary training to enable the post holder to carry out his/her duties to the required standard.
  • Undertake work in accordance with PBL Health and Safety Policies and procedures and to work within any Quality systems that are appropriate to the site.
  • Comply with all PBL policies and procedures.
  • Perform any other tasks assigned by the Line Manager.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information about the post, please contact:

recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here