Careers

Porton Biopharma has approximately 350 staff in a wide range of roles from those working in our pharmaceutical manufacturing plants, through to our quality and scientific development groups.  All focused on developing & manufacturing life-saving products that make a real difference to patients’ lives.

We are always looking for people, ranging from those with a general interest in science & technology, to ones with higher qualifications and/or experience.

This currently includes various vacancies for pharmaceutical production staff and supervisors to support our continued growth.  So if you are a motivated person who is interested in working in a high-tech environment as part of a dynamic team, then there could be a role for you.

 

 

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WE OFFER…

A friendly environment working alongside committed teams of people, who will be happy to share their knowledge and experience to allow you to develop your potential, with benefits that include:

  • a competitive salary
  • the necessary training
  • a pension scheme
  • 30 days annual leave
  • a canteen, gym and an active sports & social club
  • free on-site parking

With ongoing investment into the company and plans to increase our workforce, we are committed to being a leading life-science company that really makes a difference to patients’ lives.

To see the sort of  people that we ‘re looking for, the  Staff Profiles page has short interviews with current staff giving an overview of just some of our roles.

CURRENT VACANCIES…

PBL only accept CV’s from Recruitment Agencies with whom we have agreed Terms & Conditions.

A list of our current vacancies shown below.

To apply for a specific vacancy applicants should  send a covering letter quoting the Job Reference Number, a copy of their CV, together with a supporting statement referring to both the Job Description and Person Specification.

However, we also welcome applications from people with transferable skills that are looking for that next challenge and to develop their career.  To be considered for up-and-coming roles please send a covering letter indicating why you want to join PBL and in which area your career aspirations lie (Engineering  / Production  / Quality etc.),  along with a CV detailing your skills and experience which we can keep on file for when a suitable position becomes available.

All applications should be sent to recruitment@portonbiopharma.com.

WORK EXPERIENCE

As a business, we recognise the value that offering work-experience placements can bring and typically offer up to 4  one-week placements each year, usually in June.   All applicants must be over 16 years of age at the time of the placement, and will be chosen following a selection process.

If you are interested in applying, then send an email and covering letter stating your interest and giving reasons why we should choose you to business@portonbiopharma.com  Applications must be received by the end of November in order to be considered for the following summer’s places.

 

PBL468 Engineering Sandwich Student (Fixed Term)

Salary: £20200.00 gross per annum

Closing Date: 23rd March 2020

Reference Number: PBL468

Job Summary…

The Engineering group provides all engineering support within the highly regulated GMP production facilities at PBL. The group includes engineering functions provided by predominantly chartered professional engineers specialising in clean rooms, GMP critical utilities, production equipment, pharmaceutical facilities, and capital works delivery.

The post-holder will contribute to the activities of the group by providing support to the engineering Subject Matter Experts. They will help identify and implement small projects/initiatives relating to process and utility systems, assist in maintaining the compliance of engineering system within the GMP envelope, contribute to the root cause investigation and troubleshooting of equipment failures within the PBL manufacturing facilities and interface with key stakeholders within other departments of PBL (e.g. Production, Validation and Quality Assurance)

We are looking for…

A good communicator with a range of practical, problem solving and analytical skills relevant to an engineering role in a pharmaceutical manufacturer. The post holder will be currently enrolled in, and have completed the second year of a science degree in a relevant engineering discipline (e.g. process, chemical or mechanical engineering) at a university that supports placement students

For further information about the post, please contact:

recruitment@portonbiopharma.com

Applicants are strongly advised to explain in their application both their interests in, and how they meet criteria described above. We also strongly suggest including with your application a letter of reference from an academic tutor explaining your suitability for the placement.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL407 Process Engineer

Salary: Circa £40,000 per annum

Reference Number: PBL407

Job Summary…

The Engineering group provides all engineering support within the highly regulated GMP production facilities at PBL Porton Down. The group includes engineering functions provided by predominantly chartered professional engineers specialising in clean rooms, GMP critical utilities, production equipment, pharmaceutical facilities, and capital works delivery.

The Process Engineer is the System technical expert for all Process and Utility systems within the GMP Envelope and is responsible for identification of and managing small projects/initiatives relating to these systems and interfacing with the wider Engineering group to ensure equipment systems within the GMP envelope remain compliant with current Good Manufacturing Practice. In addition, the Process Engineer will work within an Integrated Process Team to provide operational support to the manufacture of biopharmaceutical products.

The post holder will…

Be a core member of an Integrated Process Team and will provide operational engineering support to the manufacture of biopharmaceutical products alongside other core members from the Production and Quality functions. You will have delegated responsibility from the Process Engineering Manager to design, manage and deliver process improvement projects and represent the group in the delivery of major facility expansion/refurbishment projects.

You will become the Subject Matter Expert for a variety of systems and equipment such as Autoclaves and Critical Utilities (e.g. WFI, Clean Steam, and Purified Water) within the Pharmaceutical Production Envelope. As such you will interface with key stakeholders including equipment users, capital project managers, and the site principal maintenance contractor, to ensure these critical systems remain in compliance with best industry and regulatory practice.

We are looking for…

An applicant with experience of design or operation of process or utility systems in a highly regulated industry. The ideal candidate will have existing experience in the pharmaceutical industry. The individual will be either working towards or have recently become chartered with a supporting process or chemical engineering degree.

To download the job description please click here

PBL489 QC Technician

Salary: Circa £20200.00 per annum, dependant on experience & 7% shift allowance

Closing Date: 21st February 2020

Reference Number: PBL489

Job Summary…

A crucial part of the pharmaceutical production process is undertaken by the Quality Control Department, which performs chemical and biochemical testing to ensure that the manufactured product is safe, efficacious and fit for patient use as a pharmaceutical material. The QC Technician is primarily responsible for ensuring the day to day running of the QC Analytical laboratories with daily tasks including ordering consumables, maintaining stock lists, calibration activities, waste disposal and housekeeping within QC Analytical.

The post holder will be required to work shift rotation. This rotation includes 2 weeks out of 8 weeks where the shift is 2-10pm and potential weekend working (schedule dependent).

We are looking for…

A full time, permanent QC Technician to maintain the laboratories day to day. The ideal candidate will have at least 2 A-levels in numerate / science subjects. (A degree in Chemistry, Biochemistry or related subject is desirable). Candidates with a working knowledge / experience of a regulated or cGMP environment are desirable. Other key skills include the ability to work to deadlines, organization skills and good computer literacy.

The post holder will...

  • Carry out stock checks for Laboratory and reagents
  • Place orders for routine orders and one-off items

 

  • Maintain stock lists
  • Receive and book in delivered consumables and reagents
  • Removal of out of date materials and waste from the QC laboratories
  • Assist with housekeeping in Analytical QC
  • Disposal of toxic, hazardous and non-hazardous waste generated within Analytical QC
  • Calibration and scheduled maintenance of analytical equipment
  • Routine QC testing
  • To ensure GMP documentation practices are followed when completing the necessary documentation
  • Undertake work in accordance with Porton Biopharma’s Code of Safety Practice and Quality Systems
  • Maintain training records
  • Assist with sample receipt and booking samples in to the QC department

 

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL509 Technical Support Specialist (Fermentation)

Salary: Circa £36,460 negotiable dependent upon experience

Closing Date: 21st February 2020

Reference Number: PBL509

Job Summary…

The Technical Support Specialist reports directly to the Technical Operations Manager. This position is a technical role primarily to support and improve the processes, policies, people and procedures associated with the manufacture of products at PBL. The Technical Support Specialist will have an excellent knowledge and significant experience in the field of fermentation and actively participate or lead in identifying and bringing into use new technologies, investigate and resolve technical issues, generate reports, protocols and other GxP documentation and provide technical input, advice and training as appropriate.

The post holder will…

  • Lead in the day to day fermentation processing of PBL’s products.
  • Support the management and development of improved and new processing techniques in the various fermentation processing activities.
  • Provide technical support to production staff involved in the various fermentation processes.
  • Provide troubleshooting and technical support into process investigations.
  • Collate and share technical information with internal and external bodies to benefit the production methods, teams and departments.
  • Perform process mapping and process efficiency trending.
  • Provide specialist training to staff in fermentation processing techniques and theory.
  • Identify, evaluate and adapt new technologies where appropriate and ensure that the production area operates to a high standard and complies with GMP and other regulatory standards.
  • Assist colleagues in providing technical specialist input as required, in developing production and technical strategies for the units, identifying new opportunities as they arise and responding to external queries and complaints.
  • Contribute to reports and assist on the preparation of presentations, publications and liaison with customers, collaborators and licensing agencies.
  • Support the Unit Manager in pursuance of strategic improvements to processing control.

We are looking for…

 An individual with significant relevant fermentation experience and proven practical experience of working within a fast-moving Good Manufacturing Practices (GMP) environment. The role will require the individual to have an understanding of regulatory requirements for biological products and have specific training and experience in fermentation production methods in a pharmaceutical environment. The successful candidate will be highly flexible and capable of managing several activities simultaneously, have excellent problem solving skills, strong technical writing ability, project management and hands on experience of Fermentation and Aseptic processes are essential.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL508 QC Technologist

Salary: Circa £23,500 per annum, dependant on experience & 7% shift allowance

Reference Number: PBL508

Job Summary…

A crucial part of the pharmaceutical production process is undertaken by the Quality Control Department, which performs chemical and biochemical testing to ensure that the manufactured product is safe, efficacious and fit for patient use as a pharmaceutical material. The QC Technologist is primarily responsible for testing of in process and finished product samples, to defined specifications while ensuring that work performed within the laboratories is carried out in accordance with the statutory requirements of current GMP and corporate statutory health and safety requirements. The QC Technologist is also responsible for the authoring of technical documentation and liaising with external laboratories to arrange contract testing of products.

The post holder will be required to work shift rotation. This rotation includes 2 weeks out of 8 weeks where the shift is 2-10pm and potential weekend working (schedule dependent).

We are looking for…

The ideal candidate will be educated to degree level or equivalent qualification in Chemistry, Biochemistry or other related subject. The successful candidate will have working knowledge or experience within a regulated or Good Manufacturing Practice (GMP) environment. Experience in biopharmaceutical analysis and analytical chemistry is desirable in one of the following areas; Water analysis, TOC, physical testing, UV-Vis or pharmacopoeia testing within a GMP compliant QC laboratory. Other key skills include the ability to work to deadlines, technical report writing, problem solving, the ability to work as part of a project team and good computer literacy.

 The post holder will…

  • Ensure analysis and recording of QC and stability testing is performed in compliance with the statutory requirements of cGMP.
  • Be responsible for testing in process and finished product samples to ensure that they meet the specifications established in the product licence and internal Porton Biopharma specification documents.
  • Be responsible for writing Standard Operating Procedures and their associated risk assessments to ensure that those tasks are performed safely, and other quality documents e.g. change controls, validation reports, non-conformances and CAPAs where appropriate.
  • Organise and liaise with external testing laboratories to arrange correct and on time testing to meet production deadlines or suppliers of equipment or chemicals.
  • Organise and liaise with internal departments such as validation, pharms stores and QA where required.
  • Maintain an up-to-date awareness of regulatory and scientific developments via courses, meetings and literature.
  • Undertake work in accordance with Porton Biopharma’s Code of Safety Practice and Quality Systems.
  • Maintain training records.
  • Cleaning of laboratories.
  • Performing maintenance and calibration of equipment.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL522 Senior Production Technician - FPP - 2 Year Fixed Term Contract

Salary: Starting salary £21,000 per annum, plus 30% shift enhancement

Reference Number: PBL522

Job Purpose…

This is a shift working role which will attract a salary enhancement once appointed. This Senior Production Technician post is located at Porton Down in the Fermentation Process Plant (FPP) current Good Manufacturing Practice (cGMP) pharmaceutical manufacturing facility. This facility produces therapeutic products by bacterial fermentation followed by initial phase downstream processing.

Therapeutic products produced at Porton are licensed and marketed for worldwide distribution. The FPP is undergoing significant investment and expansion as production is being increased to meet product demand.

We are looking for…

An applicant who has GCSE’s in Maths, English and Science or equivalent qualifications. In addition, they should also be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. Candidates should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. They should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

The post holder will…

Work a shift pattern which covers 24-hour, 7 day working. They will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be provided.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information about the post, please contact: recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL558 Senior QC Technologist (Fixed Term 12 month)

Salary: Circa £25,000 negotiable dependant on experience

Reference Number: PBL558

Job Summary...…….

The purpose of this role is to provide support for the QC Microbiology department at Porton Biopharma. This will include compilation of compliance documentation, including deviations, non-conformances and CAPA, change controls, protocols and reports. The holder will also to undertake and perform microbiological QC analyses in compliance with cGMP.

The post holder will…………

  • To review data produced within the QC Microbiology department and ensure compliance with GDP and regulatory requirements.
  • To write and review Standard Operating Procedures, protocols and reports in accordance with regulatory requirements.
  • To aid in departmental CAPAs and to implement any required quality improvements that may arise from this.
  • Identify and implement quality improvements within the department pro-actively.
  • To assist as a member of the QC Microbiology Team, on a day to day basis, of the Bacteriology Technical Services Unit.
  • To record and assess results from environmental and water sampling and carry out preliminary and confirmatory identification of micro-organisms.
  • To record test results clearly and accurately and perform calculations as required and to check and sign–off colleague’s results and calculations.
  • To safely operate, clean and maintain highly complex equipment to the required levels of cleanliness and operating standards and to record all such operations and maintenance.

We are looking for...…….

A candidate with significant experience of working to cGMP, with a significant knowledge of pharmaceutical Quality Assurance. The candidate must have experience in reviewing procedures, GMP documentation and data entry. The candidate should have a significant level of experience of working within ACDP containment level 2 microbiology laboratories.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

PBL540 Waters Analytical QC Manager and Stability Unit Manager (Fixed Term 18mth)

Salary: Circa £36000.00 per annum plus 7% shift allowance

Reference Number: PBL540

Job Summary...

To lead and manage a specialist GMP analytical chemistry/biochemistry laboratory to provide compliant testing of licensed pharmaceutical products; plus validation of analytical methods and expert support and advice to GMP product teams. This position will lead approximately 7 staff consisting of Senior QC Analysts, QC Analysts and QC Technicians performing essential analysis. The team tests routine water samples to EP and USP requirements and also supports in-process testing of biopharmaceutical products. In addition, the role is responsible for running a compliant stability program.

The post holder will...

Lead the Water testing and Stability teams within Quality Control Analytical including line management responsibility. The role will also support in-process testing of biopharmaceutical products and lead the stability program.

 We are looking for...

A motivated individual who is experienced in leading a team and has extensive knowledge of analytical techniques and the requirements of a stability program. The successful candidate will be experienced in using quality management systems in the pharmaceutical industry and will be able to work to tight deadlines.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL552 Senior Analytical Scientist

Salary: Circa £25,000-£30,000 per annum negotiable dependant on experience

Closing Date: 21st February 2020

Reference Number: PBL552

Job Summary…

The successful applicant will join the Analytical Method Development Team, which develops and performs analytical methods to support the manufacturing of biopharmaceutical products. These methods are used to characterise existing manufacturing processes, to guide process improvements and to support the introduction of new processes.

The post holder will…

The post holder will be involved in leading the development, optimisation, validation and implementation of analytical methods for existing and pipeline products. The post holder will also be responsible for coordinating technical transfer of assays to QC and supporting routine testing activities of samples provided by other groups within PBL.

The post holder will be expected to work to a testing schedule and meet determined deadlines using established methods; evaluate and optimise novel approaches; plan their own work; train and support junior members of staff; present and provide written and verbal updates and follow departmental policies and procedures.

We are looking for…

The applicant must be educated to at least degree level in a relevant subject. They will need to have hands-on experience of developing, optimising, validating and implementing protein analysis methods, ideally in a biopharmaceutical setting. Familiarity with a broad range of protein sample preparation and analytical methods is required. Examples of relevant techniques are: immunoassays; 1D and 2D-gel electrophoresis; enzyme activity assays; HPLC, UPLC and UV/VIS spectroscopy; and sample concentration methods. Experience of preparing technical documentation such as standard operating procedures, protocols and reports is required. The successful candidate will also be expected to maintain up-to-date knowledge of ISO, ICH guidelines, Federal Codes and other regulatory guidance relating to analytical methods and therefore awareness of the requirements of European and US cGMPs is highly desirable.

 

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL568 Senior Production Technician - FPP

Salary: Starting salary £21,000 per annum plus 30% shift enhancement

Reference Number: PBL568

Job Purpose…

This is a shift working role which will attract a salary enhancement once appointed. This Senior Production Technician post is located at Porton Down in the Fermentation Process Plant (FPP) current Good Manufacturing Practice (cGMP) pharmaceutical manufacturing facility. This facility produces therapeutic products by bacterial fermentation followed by initial phase downstream processing. Therapeutic products produced at Porton are licensed and marketed for worldwide distribution. The FPP is undergoing significant investment and expansion as production is being increased to meet product demand.

We are looking for…

An applicant who has GCSE’s in Maths, English and Science or equivalent qualifications. In addition, they should also be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. Candidates should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. They should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

The post holder will…

Work a shift pattern which covers 24-hour, 7 days working. They will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements. This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large-scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be provided.

Main Duties and Responsibilities include but not limited to;

  • Working in an automated chemical plant.
  • Operate plant and equipment using newly installed automated control systems.
  • Ensure that the various work areas are maintained at the highest state of readiness at all times.
  • Ensure that their daily activities are coordinated with other team members.
  • Work within a GMP quality system.
  • Ensure that documentation is completed within the legal frameworks.
  • Take responsibility for Non-Conformances, CAPA, Risk Assessments and Change Controls for the area and ensure SOPs and BMRs are available for use.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information or an informal discussion about the post, please contact:

Mark Poole (Unit Manager – Fermentation Production Plant)

Email mark.poole@portonbiopharma.com

Phone: 01980 612644

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL569 Production Supervisor - FPP

Salary: Circa £24,000.00 per annum, dependant on experience, plus 30% shift allowance

Closing Date: 21st February 2020

Reference Number: PBL569

Job Purpose…

Supervisors are located at various manufacturing centres at Porton Down and work in all aspects of GMP manufacturing. The production areas are involved in the manufacturing of pharmaceutical products which includes cell bank production, fermentation, downstream processing, formulation, filling, freeze drying and visual inspection of Pharmaceutical products. The facility is an FDA and MHRA licensed GMP manufacturing facility which produces therapeutic products.

We are looking for…

A candidate who is ideally educated to Degree Level or equivalent qualification, holds a Higher National Certificate and has supervisory/ management experience. The successful candidate will be self-motivated and highly organised and be able to prioritise workloads to meet often changing timescales. Experience of training staff is essential as is knowledge of cGMP requirements and how to implement them and hands-on experience in writing, reviewing and collating large numbers of documents would be desirable but not essential.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

The post holder will…

MAIN DUTIES AND RESPONSIBILITIES

Please note that the first bullet point may be modified and / or extended in order that it is bespoke to the specific Supervision role. 

  • To carry out duties involved in the manufacture of biopharmaceuticals to cGMP standards.
  • Ensure that the facility is maintained in a compliant state and that the product/materials are manufactured to appropriate regulatory requirements.
  • Responsible for data collection throughout the process.
  • Responsible for the provision of all consumables, supplies, etc. required for the process and documented storage of materials generated.
  • Manage and support junior staff in all their activities and ensure they are adequately trained in all operational processes.
  • Recognise the areas and individuals in your team where support is required. Ensure support is given either directly or via an escalated route.
  • Manage, oversee and support junior staff in all their activities and ensure they are adequately trained in all operational processes and that GMP Compliant behaviours are reinforced by all.
  • Work with the Unit Manager and Team Leader to develop, implement and perform internal self -inspections for the area to ensure that they are clearly communicating the expectations of GMP to all of their staff.
  • Responsible for ensuring that all staff adhere to, and all operations are carried out to, strict GMP guidelines.
  • To undertake all necessary training to enable the post holder to carry out his/her duties to the required standard.
  • Assist the Unit Manager/Team Leader in the completion of annual and six-monthly appraisals.
  • Ensure routine one two one discussions take place and are documented.
  • Generate and review documentation with regard to risk assessments and cGMP, e.g. SOPs, to ensure compliance of the Unit with all necessary regulations. Complete documentation and records accurately and to a high standard.
  • To assist in the raising, execution and implementation of CAPAs and change controls.
  • Assist in the completion of non-conformance investigations.
  • Required to work extended hours on critical processing days.
  • Perform a wide range of routine and some non-routine technical procedures and understand the rationale behind the procedures and practices.
  • To undertake work in accordance with PBL Health and Safety Policies and procedures and to work within any Quality systems that are appropriate to the site.
  • Ensure that documentation is completed within the legal frameworks.
  • Take responsibility for Non-Conformances, CAPA, Risk Assessments and   Change Controls for the area and ensure SOPs and BMRs are available for use.

 

For further information or an informal discussion about the post, please contact:

Mark Poole Unit Manager – Fermentation Production Plant

Email mark.poole@portonbiopharma.com

Phone 01980 612644

 

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

 

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL570 Senior QC Technologist

Salary: Circa £27,000 per annum, dependant on experience

Closing Date: 21st February 2020

Reference Number: PBL570

Job Summary

Quality Control Bacteriology Technical Services team performs specialist microbiological testing to assist licensed pharmaceutical manufacture in compliance with GMP.

The post holder will

  • Operate in compliance in GMP and quality systems
  • Knowledge and experience of Quality Management Systems including non-conformances, change management and quality risk management
  • Supervise a small team of technologists
  • Undertake and perform microbiological QC analyses in the Quality Control Bacteriology Technical Services Unit
  • Able to work with minimal supervision and to strict deadlines
  • Supervise and organise the workload, on a day to day basis, of the Bacteriology Technical Services Unit.
  • Strong understanding of QC microbiological assays, eg bioburden, endotoxin, water testing, disinfectant efficacy and environmental monitoring as well as microbial identification
  • Confident to train junior staff in processes and procedures
  • Perform data verification of test data and results

 We are looking for

We are looking for a candidate who has a high level of knowledge, understanding and practical experience of pharmaceutical microbiology. The applicant will be educated to degree level in a relevant subject or significant experience of working in a laboratory at a similar level or in a similar role. Applicant will need to demonstrate excellent communication and computer skills in addition to working with a team of microbiologists.

For further information or an informal discussion about the post, please contact: Edward Webber

 

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL571 Training Admin Supervisor

Salary: Cira £23,735 per annum, dependant on experience

Closing Date: 21st February 2020

Reference Number: PBL571

Job Summary………………..

This Training/admin Supervisor post is located at the Fermentation Process Plant (FPP) at Porton Down. The FPP unit is a current Good Manufacturing Practice (cGMP) manufacturing facility which produces bacterial raw material for the FPP by fermentation. The active ingredient is then extracted from the fermentation product by initial phase downstream processing.

Therapeutic products produced at PBL are licensed and marketed for worldwide distribution. The FPP is undergoing significant investment and expansion as production is being increased to meet product demand. This role will be one of those used to support that expansion.

We are looking for……………….

Applicants should ideally have GCSE Mathematics, English, and Science, and be educated to a minimum of NVQ level 2 in a relevant subject or have a minimum of two years significant equivalent GMP production experience. They should have significant experience in a relevant technical area and a good working knowledge of cGMP requirements and know how to implement them in the workplace. Applicants should be able to communicate clearly and possess good writing and data entry skills. Applicants should have well developed problem solving skills and experience of training individuals to set programs and protocols. Lastly applicants should have a flexible approach to work, be able to work effectively as part of a team, and be proactive and able to work on their own initiative when required.


The post holder will…………...

The post holder will report to the Unit Manager. He/she will support the Unit Manager by supervising and coordinating the training of Process Hall production technicians in all Process Hall manufacturing and support operations. They will also ensure this is performed in a timely and compliant manner to cGMP requirements. This role will involve supervising the training of newly appointed production technicians while they undertake a range of tasks, from preparation and use of operational equipment to preparation and completion of Quality documentation.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

For further information or an informal discussion about the post, please contact:

Mark Poole, Unit Manager - Fermentation Process Plant  Phone 01980 551737

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

To download the job description please click here

PBL572 QC Microbiology Lab Support Technician

Salary: Circa £20200.00 - £22000.00 per annum, dependant on experience

Closing Date: 28th February 2020

Reference Number: PBL572

Job Summary:

The post holder will be part of the QC Bacteriology Technical Services team and assist with activities which include the following:

To assist the microbiological QC Technologists in the Quality Control Bacteriology Technical Services Unit, which provides specialist microbiological testing services in support of licensed pharmaceutical manufacture at PBL, Porton Down, in compliance with cGMP.

The post holder will:

Be responsible for cleaning and monitoring of equipment in the department, housekeeping duties to ensure the smooth running of the department, maintaining stock inventories and monitor stock levels, decontamination and disposal of laboratory waste, support QC Technologists in their role in the testing of production samples, preparation of equipment for calibration, validation, servicing and maintenance.

 We are looking for:

An applicant who has an interest in science and working in a laboratory, is able to pay attention to detail and are highly organised as well as being a good communicator and team worker.

Key skills are:

  • Responsibility for cleaning, monitoring laboratory equipment, preparation of equipment logbooks and other associated GMP documentation
  • Performing routine stock and inventory checks, maintaining stock levels of media and consumables to ensure the efficient running of the department.
  • Preparing environmental monitoring consumables for for use in the department
  • Preparation of equipment for calibration, validation, servicing and maintenance
  • Incubating and reconciling environmental monitoring media plates and ensuring all documentation is completed in compliance with cGMP.
  • Decontamination and disposal of laboratory waste.

 

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL573 QA Compliance Officer (Fixed Term 12 months)

Salary: Circa £29,984.00, per annum dependant on experience

Closing Date: 13th March 2020

Reference Number: PBL573

Job Summary:

The post holder will support the audit team by completing internal and supplier audits as per the audit schedules. In addition, the post holder will review Monographs and TSE/BSE statements for the approval of suppliers, progress Supplier Questionnaires, produce Quality Technical Agreements with critical suppliers and initiate and progress Supplier Complaints.

The post holder will:

  • Work with minimal supervision and to strict deadlines.
  • Organise, plan and perform internal and external (supplier) audits and to follow up open audit reports, assist with raising CAPAs and conducting review of evidence in order to close out audit CAPAs and reports.
  • Ensure supplier questionnaires are satisfactorily completed by key manufacturers and suppliers in a timely fashion.
  • Liaise with suppliers to obtain relevant information for their approval to provide key materials and services to PBL (incl. processing, BSE/TSE)
  • Approve GMP Monographs to ensure that suppliers are appropriately approved and BSE/TSE certificates are satisfactory.
  • Produce Quality Technical Agreements for the supply of goods and services from critical suppliers
  • Initiate and progress Supplier Complaints to closure.

We are looking for:

An applicant who has excellent communication skills in addition to good customer focus with a drive and determination to succeed in maintaining current exceptional service levels.

The successful candidate will have educated to degree level or HND (e.g. Microbiology, or a related subject) or a demonstrable equivalent level of experience of working at a similar level. Proven experience in auditing both internally and externally to GMP and experience working in a GMP QA environment is essential.

Candidates must hold a British or European passport and must be able to travel world-wide on a regular basis.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here