Careers

Porton Biopharma has approximately 350 staff in a wide range of roles from those working in our pharmaceutical manufacturing plants, through to our quality and scientific development groups.  All focused on developing & manufacturing life-saving products that make a real difference to patients’ lives.

We are always looking for people, ranging from those with a general interest in science & technology, to ones with higher qualifications and/or experience.

This currently includes various vacancies for pharmaceutical production staff and supervisors to support our continued growth.  So if you are a motivated person who is interested in working in a high-tech environment as part of a dynamic team, then there could be a role for you.

 

 

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WE OFFER…

A friendly environment working alongside committed teams of people, who will be happy to share their knowledge and experience to allow you to develop your potential, with benefits that include:

  • a competitive salary
  • the necessary training
  • a pension scheme
  • 30 days annual leave
  • a canteen, gym and an active sports & social club
  • free on-site parking

With ongoing investment into the company and plans to increase our workforce, we are committed to being a leading life-science company that really makes a difference to patients’ lives.

To see the sort of  people that we ‘re looking for, the  Staff Profiles page has short interviews with current staff giving an overview of just some of our roles.

CURRENT VACANCIES…

PBL only accept CV’s from Recruitment Agencies with whom we have agreed Terms & Conditions.

A list of our current vacancies shown below.

To apply for a specific vacancy applicants should  send a covering letter quoting the Job Reference Number, a copy of their CV, together with a supporting statement referring to both the Job Description and Person Specification.

However, we also welcome applications from people with transferable skills that are looking for that next challenge and to develop their career.  To be considered for up-and-coming roles please send a covering letter indicating why you want to join PBL and in which area your career aspirations lie (Engineering  / Production  / Quality etc.),  along with a CV detailing your skills and experience which we can keep on file for when a suitable position becomes available.

All applications should be sent to recruitment@portonbiopharma.com.

WORK EXPERIENCE

As a business, we recognise the value that offering work-experience placements can bring and typically offer up to 4  one-week placements each year, usually in June.   All applicants must be over 16 years of age at the time of the placement, and will be chosen following a selection process.

If you are interested in applying, then send an email and covering letter stating your interest and giving reasons why we should choose you to business@portonbiopharma.com  Applications must be received by the end of November in order to be considered for the following summer’s places.

 

Flexible Working opportunities

Salary: dependant

Reference Number: PBL flexi

We are offering part-time opportunities to people who can contribute to the manufacturing of our life-saving products by providing general cleaning and support activities in our pharmaceutical production facilities, on a part-time basis.

We are looking to put together a team  and are considering what we can offer as an employer, so if you would like to contribute to our success and believe that you could play your part then we would like to hear from you.  Please send us a covering letter providing details of your typical availability and g quoting refrence PBL flexi.

PBL 223 Production Technician

Salary: Starting salary £20,220 negotiable dependent upon experience

Reference Number: PBL223

We are looking for...

Applicants should have GCSE in Maths, English and Science. In addition, candidates should be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. They should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. Candidates should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should have a flexible approach to work, be able to work effectively as part of a team, and be proactive and able to work on their own initiative when required.


The post holder will...

Assist with the varied support tasks that are performed within the FPP process hall. These tasks include environmental monitoring, water sampling, calibration checks, cleaning, laundry processing and dispatch, and ordering and maintaining supplies of consumables. Accurate completion of Quality documents will be required. Driving will also be required to ensure compliant delivery of production samples to the PBL main site. Lastly the post holder will require good communication skills to interact concisely with management, peers and junior members of staff.

He/she will support the Team Leader to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements

Successful applicants must either hold, or be capable of obtaining a UK government security clearance at SC level. To obtain clearance at this level you must have been resident in the UK for the last five years, and not have lived abroad for more than six months out of the last twelve.

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

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PBL368 Production Technician - Seed Unit

Salary: Starting salary £20,220 per annum/pro rata negotiable dependent upon experience + 10% shift allowance

Closing Date: 30th August 2019

Reference Number: PBL368

Job Purpose / Summary

 The successful candidate will assist the FPP Support Team with the routine tasks that are performed within the process hall including cleaning, environmental monitoring, water sampling, calibration checks, ordering and maintaining supplies of consumables. Some driving will be required to ensure delivery of samples and good communication with other members of staff.

We are looking for…

The successful applicant will preferably have prior experience of working within a GMP environments and have an interest in microbiology and the enthusiasm to pursue a career working in pharmaceuticals. You will have the ability to keep clear and accurate records and to follow written procedures as well as having excellent communication skills with a flexible approach to work.

This role can be taken as a part-time or full-time position; however this must include Saturday and Sunday working.

 The post holder will …

  • Function as part of the team responsible for cleaning of the FPP Main Process Hall, Seed Production Unit and periphery.
  • Assist with Environmental Monitoring of the FPP Main Process Hall.
  • Assist with the water sampling of the FPP Main Process Hall.
  • Assist with transporting product, materials, and equipment to and from the Main PHE site.
  • Assist with the ordering, stocking up, and maintenance of consumables.
  • Ensure compliance is maintained during manufacture and that PBL policies and procedures are applied when necessary.
  • Liaise with Pharmaceutical Stores, Quality Control and EMCOR to ensure the unit stays within compliance and is ready for operations when required.
  • Ensuring training is completed and up to date for their required area of work.

For further information or an informal discussion about the post, please contact:

Recruitment@portonbiopharma.com

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their covering letter to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

 

To download the job description please click here

PBL375 QC Microbiology Technologist

Salary: Circa £23500.00 per annum, dependant on experience

Closing Date: 4th October 2019

Reference Number: PBL 375

Job Summary………..

The post holder will be part of the QC Bacteriology Technical Services team and assist with activities which include the following:

To undertake and perform microbiological QC analyses in the Quality Control Bacteriology Technical Services Unit, which provides specialist microbiological testing services in support of licensed pharmaceutical manufacture at PBL, Porton Down, in compliance with cGMP.

 The post holder will…………

  • Undertake and perform microbiological QC analyses in support of Porton Biopharma’s licensed production, service, validation and developmental programs.
  • Carry out all work in compliance with cGMP
  • Test microbiological samples from all stages of the production processes of licensed and developmental products and to assess the results against pre-set standards and specifications
  • Undertake identification of micro-organisms isolated from microbiological tests and samples
  • Record all information and data clearly and accurately
  • Pre-test media used within QC and Production against pre-set specifications
  • Maintain the Bacteriology Technical Services Culture Collection, media stocks, and necessary consumables to ensure the efficient running of the group
  • Safely operate, clean and maintain laboratory equipment to the required levels of cleanliness and operating standards
  • Provide cover for and assist the Environmental Monitoring team when required

 We are looking for……………….

An applicant who has good interpersonal skills and able to work as part of a team and is methodical and reliable with the ability to think clearly, the ability to learn and able to respond to changes in schedule and demands. The applicant will need to have knowledge and experience of microbiology gained in a laboratory or similar environment and ideally have experience of working in a Good Manufacturing Practice GMP or similarly regulated environment.

Key skills are:

  • Knowledge and experience of microbiology gained in a laboratory or similar environment.
  • An understanding of GMP and quality systems
  • Able to work methodically and to strict deadlines
  • To perform routine testing within the microbiology laboratory, on a day to day basis, of the Bacteriology Technical Services Unit.
  • Good understanding of QC microbiological assays and QC laboratory systems
  • Confident to train junior staff in processes and procedures

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL407 Process Engineer

Salary: £29,355 negotiable dependent upon experience

Reference Number: PBL407

Job Summary…

The Engineering group provides all engineering support within the highly regulated GMP production facilities at PBL Porton Down. The group includes engineering functions provided by predominantly chartered professional engineers specialising in clean rooms, GMP critical utilities, production equipment, pharmaceutical facilities, and capital works delivery.

The Process Engineer is the System technical expert for all Process and Utility systems within the GMP Envelope and is responsible for identification of and managing small projects/initiatives relating to these systems and interfacing with the wider Engineering group to ensure equipment systems within the GMP envelope remain compliant with current Good Manufacturing Practice. In addition, the Process Engineer will work within an Integrated Process Team to provide operational support to the manufacture of biopharmaceutical products.

The post holder will…

Be a core member of an Integrated Process Team and will provide operational engineering support to the manufacture of biopharmaceutical products alongside other core members from the Production and Quality functions. You will have delegated responsibility from the Process Engineering Manager to design, manage and deliver process improvement projects and represent the group in the delivery of major facility expansion/refurbishment projects.

You will become the Subject Matter Expert for a variety of systems and equipment such as Autoclaves and Critical Utilities (e.g. WFI, Clean Steam, and Purified Water) within the Pharmaceutical Production Envelope. As such you will interface with key stakeholders including equipment users, capital project managers, and the site principal maintenance contractor, to ensure these critical systems remain in compliance with best industry and regulatory practice.

We are looking for…

An applicant with experience of design or operation of process or utility systems in a highly regulated industry. The ideal candidate will have existing experience in the pharmaceutical industry. The individual will be either working towards or have recently become chartered with a supporting process or chemical engineering degree.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL411 Aseptic Processing Specialist

Salary: Starting salary £29,355 negotiable dependent upon experience

Reference Number: PBL411

Job Purpose…

This position will report to the Aseptic Processing Functional Manager and will provide technical specialist support to all aseptic processing activities in the manufacture of Erwinase, Anthrax vaccine and other PBL products. The role will work cross functionally and be involved in current projects, new projects and all manufacturing activities that require aseptic processing input. It is expected that the role will typically focus on day to day aseptic processing matters within Production but may also be required to support projects designed to improve and develop PBL’s aseptic processing strategy.

We are looking for…

An individual who is educated to degree level or equivalent in a relevant discipline. The successful candidate should have a minimum of 5 years’ experience within Biopharma / Pharma aseptic GMP environments and have an in depth understanding of aseptic processing and techniques. You will need to have an understanding of regulatory requirements for biological products and experience in the implementation of new technologies and equipment into GMP manufacture and will have proven experience of generating GMP documents within a quality system. Experience of delivering specialised technical training and report writing and data trending evaluation would be desirable but not essential. The successful applicant will have a flexible approach to work and be able to deliver to schedules.

The post holder will…

  • Lead in the day to day aseptic processing of PPL’s products.
  • Support the management and development of improved and new processing techniques in the various aseptic processing activities.
  • Provide technical support to production staff involved in the various aseptic processes.
  • Provide troubleshooting and technical support into process investigations.
  • Collate and share technical information with internal and external bodies to benefit the production methods, teams and departments.
  • Perform process mapping and process efficiency trending.
  • Provide specialist training to staff in aseptic processing techniques and theory.
  • Identify, evaluate and adapt new technologies where appropriate and ensure that the production area operates to a high standard and complies with GMP and other regulatory standards.
  • Assist colleagues in providing technical specialist input as required, in developing production and technical strategies for the units, identifying new opportunities as they arise and responding to external queries and complaints.
  • Contribute to reports and assist on the preparation of presentations, publications and liaison with customers, collaborators and licensing agencies.
  • Support the Functional Manager Aseptic Processing in pursuance of strategic improvements to aseptic processing control.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL433 QC Micro Technologist

Salary: Circa £23,735 per annum, negotiable dependant on experience

Reference Number: PBL433

Job Summary………………..

The post holder will be part of the QC Bacteriology Technical Services team and assist with activities which include the following:

To undertake and perform microbiological QC analyses in the Quality Control Bacteriology Technical Services Unit, which provides specialist microbiological testing services in support of licensed pharmaceutical manufacture at PBL, Porton Down, in compliance with cGMP.

The post holder will have…………

  • Knowledge and experience of microbiology gained in a laboratory or similar environment.
  • An understanding of GMP and quality systems
  • Able to work methodically and to strict deadlines
  • To perform routine testing within the microbiology laboratory, on a day to day basis, of the Bacteriology Technical Services Unit.
  • Good understanding of QC microbiological assays and QC laboratory systems
  • Confident to train junior staff in processes and procedures.

 We are looking for……………….

An applicant who has good interpersonal skills and able to work as part of a team and is methodical and reliable with the ability to think clearly, the ability to learn and able to respond to changes in schedule and demands. The applicant will need to have knowledge and experience of microbiology gained in a laboratory or similar environment and ideally have experience of working in a Good Manufacturing Practice GMP or similarly regulated environment.

To apply for this position please submit a CV and cover letter to recruitment@portonbiopharma.com using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL465 QC Microbiology Manager

Salary: Circa £50,000 per annum

Reference Number: PBL465

Job Purpose…

The successful candidate will lead the Microbiology Department to successfully deliver quality products on time in full. This role will provide Line Management for 4 area managers supervising established teams within the Microbiology Department. The overall team equates to approximately 30 quality professionals.

The post holder will…

  • Work with other managers within the Quality team to ensure that manufacturing and quality activities are performed in compliance with all the regulations and other requirements including: The Rules & Guidance for Pharmaceutical Manufacturers' and Distributors, cGMP guidance, and other regulations governing PBL activities.
  • Lead projects and deliver required outcomes in their own specialist area.
  • Lead, motivate, coach, mentor and manage the performance and output of the Microbiology Team (including direct managerial reports) and ensure that all team objectives are met in agreed timescales.
  • Maintain and develop the local standard operating procedures to secure effective working practices as well as compliance with relevant national, European and US legislation.
  • Monitor the performance of the systems under area of responsibility using KPIs and report to management.
  • Develop and implement an ongoing Quality Improvement Plan related to the systems under area of responsibility
  • Lead the development and implementation of an ongoing Health & Safety Plan for the team to secure the right level of performance, highlight failures and make recommendations for solutions.
  • In line with overall responsibilities, perform additional tasks assigned by the line manager.

We are looking for…

A highly motivated quality professional with drive and passion to inspire and deliver through the team reporting to them. They will be educated to degree level or equivalent in an appropriate scientific discipline and a post-graduate degree in life/applied science or equivalent would be desirable. The successful applicant will be a strong manager with an up to date microbiology background and proven experience in the pharma industry. The post holder will be customer focused, deliver continuous improvement activities and be a subject matter expert for microbiological issues encountered during the manufacturing and testing of PBL licensed products. Previous experience of managing laboratory staff and associated activities is essential.

The successful applicant should be prepared to participate in out of hours on call Rota if required and be prepared to meet the requirements of manufacturing schedules which may include working out of hours or weekends.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL485 QC Technologist (Monitoring and Training)

Salary: Starting salary £23,735 per annum negotiable dependent upon experience

Reference Number: PBL485

Job Purpose…

To provide specialist training in microbiological environmental monitoring methods, cleanroom gowning, aseptic practices and water sampling. The successful candidate will also be required to undertake microbiological environmental monitoring of critical pharmaceutical manufacturing operations to support the Sterility Assurance Program. To supervise, oversee, observe and qualify all production technologists and other staff where applicable, in gowning, microbiological environmental monitoring methods and water sampling.

We are looking for…

A candidate who has previous experience of working in cleanrooms, performing environmental monitoring and training of other members of staff to join the Environmental Monitoring Team within QC Biological Services. A degree in a relevant scientific discipline is desirable but not essential. The candidate should also have a good understanding of QC Microbiology laboratory testing. Applicants must have a flexible approach to working and be able to comply with SAPO regulations and must have a current valid right to work in the UK.

The post holder will…

  • Operate in compliance with cGMP.
  • Train and qualify all Production and other staff, as necessary, in the techniques and procedures for microbiological environmental monitoring.
  • Train and qualify all Production and other staff, as necessary, in water sampling.
  • Train and qualify all Production and other staff, as necessary, in procedures for gowning.
  • Oversee, supervise and observe Production and other staff undertaking environmental monitoring and water sampling to ensure continued compliance.
  • Re-qualify Production and other staff at a defined frequency, as required by GMP.
  • Plan and organise schedules for training, qualifications and observations.
  • Assess staff competence in environmental monitoring, water sampling and gowning procedures. Sign training documentation and produce certificates for trained members of staff.
  • Carry out and record microbiological environmental monitoring for critical manufacturing operations, and routine monitoring where required.
  • Input microbiological environmental monitoring and water sampling data into appropriate databases and spreadsheets.
  • Be involved in the writing and updating of Standard Operating Procedures relating to environmental monitoring and water sampling, either as the author, or by providing technical information and advice to the author.
  • Attend training courses that contribute to the efficiency of the operating systems and are beneficial to the post holder’s personal development.
  • Follow operating procedures at all times and ask for advice when necessary.
  • Undertake all work in accordance with Porton Down’s Code of Safety Practice and Quality Systems.
  • To prepare environmental summary reports of production processes for insertion into documents, reports and batch manufacturing records as part of batch release.
  • To investigate out-of-specification water and environmental monitoring test results in conjunction with the Compliance Team and review resulting Non-Conformances, participating in Ishikawa and 5-Whys investigations, where necessary.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL492 Senior Production Technician PPC

Salary: Cira £20,200, dependant on experience

Reference Number: PBL492

Job Purpose…

This post is located within Zones1-4 of the Pharmaceutical Production Centre (PPC). PPC Zones 1-4 is dedicated to the manufacture of Erwinase within two manufacturing sub units the Therapeutics Protein Unit (TPU) and Product Finishing Unit (PFU), both units are GMP manufacturing facilities. TPU performs downstream purification of the therapeutic products and PFU performs aseptic processing and final fill, freeze drying and visual inspection of the product. The team is responsible for the production of pharmaceutical products, preparation of components and the operation of production equipment. Day to day tasks also include maintaining the facility via specialist cleaning procedures, monitoring environmental conditions and performing aseptic processes within a cleanroom environment.

The post holder will…

Report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring activities supporting manufacturing are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment, to completion of Quality documentation. Full training will be provided where required.

We are looking for…

Applicants should have a GCSE in Maths, English and Science. They should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. Candidates should be able to communicate clearly, possessing good writing and data entry skills. Candidates will need to have a flexible approach to work, be able to work effectively as part of a team as well as being proactive and able to work on their own initiative.

For further information about the post, please contact:recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL505 Unit Supervisor

Salary: Starting salary £22,660 negotiable dependent upon experience

Reference Number: PBL505

Job Purpose…

The post is located within the Product Finishing Unit (PFU). PFU is a GMP manufacturing facility focused on the filling, freeze drying and visual inspection of pharmaceutical products. Working in a highly regulated environment, you’ll be supervising a small team working in the production of pharmaceutical products or the operation of production equipment used in the preparation of components.

The post holder will…

The post holder will report to and support the Team Leader by supervising manufacturing operations and ensuring they are performed in a timely and compliant manner to cGMP requirements. This role will involve supervising a team of technicians while they undertake a range of tasks, from preparation and use of operational equipment to preparation and completion of Quality documentation. Full training will be provided where required.

Main duties include but are not limited to:

  • Carry out duties involved in the manufacture of biopharmaceuticals to GMP and ISO 9001 requirements as directed.
  • Ensure that the facility is maintained in a compliant state and that the product/materials are manufactured to appropriate regulatory requirements.
  • Responsible for the provision of all consumables, supplies, etc. required for the process and documented storage of materials generated.
  • Manage and support junior staff in all their activities and ensure they are adequately trained in all operational processes.
  • Responsible for ensuring that all staff adhere to, and all operations are carried out to, strict GMP guidelines.
  • To undertake all necessary training to enable the post holder to carry out his/her duties to the required standard.
  • Assist the Unit Manager/Team Leader in the completion of annual and six-monthly staff appraisals.
  • Generate and review documentation with regard to risk assessments and cGMP, e.g. SOPs, to ensure compliance of the Unit with all necessary regulations. Complete documentation and records accurately and to a high standard.
  • To assist in the timely closure of non-conformances, CAPAs and change controls.
  • Work accurately with good hand and eye co-ordination, sometimes for prolonged periods of time.
  • Required to work extended hours on critical processing days.
  • Perform a wide range of routine and some non-routine technical procedures and understand the rationale behind the procedures and practices.
  • To undertake work in accordance with PBL Health and Safety Policies and procedures and to work within any Quality systems that are appropriate to the site.

 

We are looking for…

 Applicants should be educated to an HNC level (or equivalent) or have significant equivalent GMP production experience. They should also have significant experience in a relevant technical area and a good working knowledge of cGMP requirements and how to implement them in the workplace. Candidates should be able to communicate clearly and possess good writing and data entry skills and have well-developed problem-solving skills and the ability to respond to sudden unexpected demands. Lastly applicants should have a flexible approach to work, be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL508 QC Technologist (Waters)

Salary: Starting salary £22,660 negotiable dependent upon experience plus 7% shift enhancement

Reference Number: PBL508

Job Purpose…

A crucial part of the pharmaceutical production process is undertaken by the Quality Control Department, which performs chemical and biochemical testing to ensure that the manufactured product is safe, efficacious and fit for patient use as a pharmaceutical material. The QC Technologist is primarily responsible for testing of in process and finished product samples, to defined specifications while ensuring that work performed within the laboratories is carried out in accordance with the statutory requirements of current GMP and corporate statutory health and safety requirements. The QC Technologist is also responsible for the authoring of technical documentation and liaising with external laboratories to arrange contract testing of products.

The post holder will be required to work shift rotation. This rotation includes 2 weeks out of 8 weeks where the shift is 2-10pm and potential weekend working (schedule dependent).

The post holder will…

  • Ensure analysis and recording of QC and stability testing is performed in compliance with the statutory requirements of cGMP.
  • Be responsible for testing in process and finished product samples to ensure that they meet the specifications established in the product licence and internal Porton Biopharma specification documents.
  • Be responsible for writing Standard Operating Procedures and their associated risk assessments to ensure that those tasks are performed safely, and other quality documents e.g. change controls, validation reports, non-conformances and CAPAs where appropriate.
  • Organise and liaise with external testing laboratories to arrange correct and on time testing to meet production deadlines or suppliers of equipment or chemicals.
  • Organise and liaise with internal departments such as validation, pharms stores and QA where required.
  • Maintain an up-to-date awareness of regulatory and scientific developments via courses, meetings and literature.
  • Undertake work in accordance with Porton Biopharma’s Code of Safety Practice and Quality Systems.
  • Maintain training records.
  • Cleaning of laboratories.
  • Performing maintenance and calibration of equipment.

We are looking for…

The ideal candidate will be educated to degree level or equivalent qualification in Chemistry, Biochemistry or other related subject. The successful candidate will have working knowledge or experience within a regulated or Good Manufacturing Practice (GMP) environment. Experience in biopharmaceutical analysis and analytical chemistry is desirable in one of the following areas; Water analysis, TOC, physical testing, UV-Vis or pharmacopoeia testing within a GMP compliant QC laboratory. Other key skills include the ability to work to deadlines, technical report writing, problem solving, the ability to work as part of a project team and good computer literacy.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL510 Maintenance Team Leader

Salary: Starting Salary £29,355. Negotiable dependent upon experience

Closing Date: 27th September 2019

Reference Number: PBL510

Job Summary…

Lead, motivate and manage the development of the Main Site Maintenance Team and provide expertise in a cross functional group responsible for the delivery of Maintenance within Porton Biopharma Limited (PBL). The post holder also has overall supervisory responsibility for external service providers contracted to PBL specifically to deliver specialized support in the service of critical facilities and equipment.

The post holder will…

  • Ensure all maintenance activities under the positions responsibility are delivered in a timely manner to prevent delay to production.
  • Lead, motivate and manage the development of the Main Site Maintenance Team and provide expertise in a cross functional group responsible for the delivery of Engineering within Porton Biopharma (PBL).
  • Day to day management of Maintenance activities and associated resource planning to meet the requirements of defined schedules.
  • Coordination with the Asset Management Team to ensure notice is given for the requirement of spares.
  • Generation of non-conformance documentation.
    • Looking after contractors when on site and ensuring they are operating according to the RAMS provided.
    • Working within the confines of the PBL permit to work system.
  • Implement and manage a process of good housekeeping.
  • Manage the Maintenance Teams required training levels.
  • Lead the development and implementation of quality improvement plans to maximize the efficiency of the Maintenance Team.
    • To perform any other duties required by the Line manager commensurate with grade.
    • To undertake work in accordance with the PBL’s Health and Safety policies and procedures and to work within any Quality Systems that are applicable to the site to comply with all PBL policies and procedures

We are looking for…

A candidate who is educated to NVQ Level or equivalent qualification/apprenticeship in a relevant subject or who has significant experience of working at a similar level within a specialist area. The ideal candidate will have maintenance experience ideally within the Pharmaceutical Industry and will have experience working within a regulated environment. Applicants must have experience in supervising a multi-disciplinary team and knowledge of Engineering Health & Safety Legislation and its application to maintenance operations.

For further information or an informal discussion about the post, please contact:

Stuart.naylor@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL511 Production Technician

Salary: Cira £20,200, dependant on experience

Reference Number: PBL511

Job Summary………………..

The position is in the Immuno team who produce Anthrax Vaccine. The successful applicant will be responsible for manufacturing Anthrax Vaccine to cGMP standards as well as standard housekeeping tasks to keep the unit compliant

 The post holder will…………

  • Perform a range of routine Production and some non-routine technical procedures and understand the rationale behind the procedures and practices.
  • Undertake all work in accordance with PBL’s Code of Safety Practice, Quality System and all other regulatory requirements.
  • Follow defined procedures, policies, rules, regulations and guidelines for all activities to ensure product meets the required standard.
  • Generate and review documentation with regard to Risk Assessments and cGMP to ensure compliance of the unit with all necessary regulations.
  • Work diligently at all times. Complete documentation and records accurately and to a high standard.
  • Ensure the unit is maintained in a compliant state. Work to cGMP following Standard Operating Procedures (SOPs) and Codes of Practice. Keep updated on new rules and regulations.
  • Perform and record environmental monitoring and water sampling in cGMP areas in accordance with documented procedures. Monitor and record air pressures and hot and cold facility temperatures.
  • Analyse information and make decisions based on assessment.
  • Assist validation department with validation protocols on equipment.
  • Maintain and use a variety of laboratory equipment.
  • Work with a range of hazardous and non-hazardous chemicals.
  • Be competent in and perform aseptic techniques.
  • Be qualified to work in a clean room environment and in containment level 3 suites.
  • Work accurately and with good hand eye co-ordination, sometimes for prolonged periods of time.
  • Operate autoclaves and sterilising ovens and have an appropriate level of understanding to review cycle data as a senior operator.

We are looking for……………….

A well organised person with good documentation skills and work ethic. Previous GMP experience will be beneficial but not essential as training will be provided.

For further information or an informal discussion about the post, please contact:

Graham Douglas on 01980 557102 or graham.douglas@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd to recruitment@portonbiopharma.com

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL515 QC Technician

Salary: Circa £20,220 per annum, negotiable dependant on experience

Closing Date: 27th September 2019

Reference Number: PBL515

Job Summary …

The Biological Technical Services Group within Quality Control at Porton Down provides a specialist ACDP level 2 and 3 containment testing service. Both microbiological and bioassay testing is performed for products manufactured by the production and product development groups.

The post holder will…

The post holder will support the work being performed within QC BTSG by maintaining a clean environment and stocking essential laboratory supplies. Microbiology laboratory testing will be carried out after training and post holder will assist with complex specialist testing within the facilities.

The post holder will be required to maintain the highest standards of data integrity.

 We are looking for…

Applicants should have a GSCEs or equivalent in Maths, English and Science. Candidates should be able to communicate clearly, possessing good writing and data entry skills. Candidates will need to have a flexible approach to work, be able to work effectively as part of a team as well as being proactive and able to work on their own initiative.

For further information or an informal discussion about the post, please contact: recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL528 Unit Manager Immuno

Salary: Circa £29000.00 - £43000.00 per annum, negotiable dependant on experience

Reference Number: PBL528

Job Summary………………..

 Unit Managers are located at various manufacturing centres at Porton Down. The facility is an FDA and MHRA licensed GMP manufacturing facility which produces therapeutic products using various chemical and natural techniques.

The post holder will…………

 Manage and supervise the output of a small team in a high-pressure manufacturing environment.

Work in a highly regulated pharmaceutical manufacturing area.

Ensure that the various work areas are maintained at the highest state of readiness at all times.

Ensure that the daily activities of staff are coordinated with other team members.

Work within a GMP quality system.

Ensure that documentation is completed within the legal frameworks.

Take responsibility for Non- Conformances, CAPA, Risk Assessments and Change Controls for the area and ensure SOPs and BMRs are available for use.

We are looking for……………….

 The successful candidate will be self-motivated, well organised and have been educated to degree level or equivalent. Previous experience managing a small team is essential. The candidate will be part of a team responsible for a series of tasks in a number of different areas.

For further information or an informal discussion about the post, please contact:

Brian Lumby Deputy Head of Production by email brian.lumby@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL532 Senior Production Technician (Seed Unit)

Salary: Cira £20,200 - £26,260, dependant on experience

Reference Number: PBL532

Job Summary………………..

The post holder will report to the Seed Room Supervisor. They will support the Seed Room Supervisor by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements. This role will involve undertaking a range of tasks, from preparation and use of operational equipment, seed culture manufacture, preparation of production medium, completion and review of Quality documentation, routine cleaning and environmental monitoring. Full training will be given where required, some cross training between units is required.

The post holder will…………

Be involved in the manufacture of life saving therapeutic vaccines. The post involves working in aseptic high-grade cleanroom environments manufacturing Erwinase working seed culture. The post also includes activities such as maintenance and monitoring of the facility, manufacture of media and completion of GMP records.

We are looking for……………….

Qualifications in GCSE Maths, English and Science are essential, further relevant qualifications or experience are desirable. The successful candidate will be an excellent communicator with good data entry skills, the ability to work well in a team and demonstrate problem solving abilities.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

 

To download the job description please click here

PBL531 Senior Analytical Scientist & Quality Management System Coordinator

Salary: Cira £30,000-£37,000.00, dependant on experience

Closing Date: 13th September 2019

Reference Number: PBL531

Job Purpose………………..

The Development Group forms the overall R&D function of Porton Biopharma Ltd. The Development Group is organised into 4 core operational teams responsible for in vitro culture processes, downstream processes, analytical method development and product development respectively. This is a dual role in which the post holder will work operationally within the analytical team as a senior analytical scientist working to develop analytical methods and conduct analytical testing of products and processes under development. In addition, coordinate activities towards implementation and management of the Quality Management System (QMS) across the development group in line with requirements of ISO9001:2015. The primary role being laboratory based and progression of technical projects the secondary role to support and coordinate the QMS.

The post holder will…………

The successful candidate will be involved in routine testing of samples provided by other groups within PBL and leading the development of analytical methods for the analysis of biopharmaceutical products. He or she will also be involved in developing, optimising, validating and implementing analytical methods and technical transfer of assays to QC.

The post holder will be expected to work to a testing schedule and meet determined deadlines using established methods; evaluate and optimise novel approaches; plan their own work; train and support junior members of staff; present and provide written and verbal updates and follow departmental policies and procedures. In addition, the role will require the individual to improving existing methodology, develop novel and new analytical methods, products and technologies.

The post holder will be involved in supporting the implementation, management, maintenance and continuous improvement of the ISO9001:2015 Quality Management System. This will include coordinating and documenting the internal audit system, reviewing QMS efficiency, writing quality documents and ensuring ongoing compliance with ISO9001:2015 and other industrial regulations.

 We are looking for……………….

Education to at least degree level in a relevant subject is essential as are a basic understanding of protein chemistry and knowledge of analytical tests performed on proteins. The post holder must have general laboratory experience, preferably direct experience of working in an analytical laboratory outside the academic setting, where he or she will have been employing chromatography techniques. Experience of using UV/Vis spectrophotometers and/or microplate readers to perform assays as well as performing gel electrophoresis techniques would also be desirable. The role requires good people management skills as well as the ability to manage multiple technical projects with the aim of meeting set deadlines.

The successful candidate must have experience of working to the requirements of a quality system such as ISO9001:2015 or GMP. Experience of maintaining, managing, implementing and improving QMS systems is also required. Good management of time and multiple tasks as well as meeting tight deadlines is also required.

Applicants must demonstrate attention to detail and an enthusiasm for analytical work. Good written and verbal communication skills and proficiency in MS Office and other relevant software are also required.

The successful candidate will also be expected to maintain up-to-date knowledge of ISO, ICH guidelines, Federal Codes and other regulatory guidance relating to analytical methods and therefore awareness of the requirements of European and US cGMPs is highly desirable.

For further information or an informal discussion about the post, please contact:

Dr Alka Bishop (alka.bishop@portonbiopharma.com) or Stuart Smith (stuart.smith@portonbiopharma.com)

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL537 Cleaning Validation Technologist

Salary: Circa £35000.00 depending on experience

Closing Date: 27th September 2019

Reference Number: PBL537

Job Purpose / Summary

This role is for the timely execution and completion of cleaning validation and cleaning verification activities in support of the PBL manufacturing facilities and regulatory requirements.  The role includes the writing, review and execution of cleaning validation/verification test protocol documents and reports, the coordination of supporting activities, the execution and completion of cleaning validation/verification activities against approved test protocols, on time, and to a high standard of documentation.

 The post holder will:

Have experience within the pharmaceutical and/or biopharma industry; Be experienced with the planning, writing and execution or validation test protocols, and subsequent assessment and presentation of results within test protocol and report documents.

The post holder will also have experience within a Cleaning Validation role; be competent with basic Microsoft Office software, including Word and Excel; and have demonstrated awareness of Lean Manufacturing techniques.

 We are looking for:
An enthusiastic candidate who can communicate effectively at all levels, and across multi-disciplinary teams, to support the completion of cleaning validation and cleaning verification activities to satisfy compliance and regulatory commitments, in addition to the continuous improvement of equipment cleaning processes at PBL.

For further information or an informal discussion about the post, please contact:

Recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

To download the job description please click here

PBL539 QC Microbiology Technologist

Salary: Circa £23,500

Reference Number: PBL539

Job Purpose…

The post holder will be part of the QC Bacteriology Technical Services team and assist with activities which include the following:

To undertake and perform microbiological QC analyses in the Quality Control Bacteriology Technical Services Unit, which provides specialist microbiological testing services in support of licensed pharmaceutical manufacture at PBL, Porton Down, in compliance with cGMP.

The post holder will…

  • Undertake and perform microbiological QC analyses in support of Porton Biopharma’s licensed production, service, validation and developmental programs
  • Carry out all work in compliance with cGMP
  • Test microbiological samples from all stages of the production processes of licensed and developmental products and to assess the results against pre-set standards and specifications
  • Undertake identification of micro-organisms isolated from microbiological tests and samples
  • Record all information and data clearly and accurately
  • Pre-test media used within QC and Production against pre-set specifications
  • Maintain the Bacteriology Technical Services Culture Collection, media stocks, and necessary consumables to ensure the efficient running of the group
  • Safely operate, clean and maintain laboratory equipment to the required levels of cleanliness and operating standards
  • Provide cover for and assist the Environmental Monitoring team when required

 We are looking for…

An applicant who has good interpersonal skills, is able to work as part of a team and is methodical and reliable with the ability to think clearly. The successful applicant will have the ability to learn and be able to respond to changes in schedule and demands. They will need to have knowledge and experience of microbiology gained in a laboratory or similar environment and ideally have experience of working in a Good Manufacturing Practice (GMP) or similarly regulated environment.

Key skills are:

  • Knowledge and experience of microbiology gained in a laboratory or similar environment
  • An understanding of GMP and quality systems
  • Able to work methodically and to strict deadlines
  • To perform routine testing within the microbiology laboratory, on a day to day basis, of the Bacteriology Technical Services Unit.
  • Good understanding of QC microbiological assays and QC laboratory systems
  • Confident to train junior staff in processes and procedures

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL491 Visual Inspection Production Technician

Salary: Starting salary £20,220 per annum negotiable dependent upon experience

Reference Number: PBL491

Job Purpose…

This post is part of the Product Finishing team within PBL’s Pharmaceutical Production Unit which is responsible for duties including media and equipment preparation, assisting with purification and formulation of Erwinase Drug Substance, sterile filtration, and aseptic processing within a Good Manufacturing Process (GMP) department.

This post will involve training and qualification in the visual inspection process. Once qualified, the post will involve manual visual inspection of all Erwinase vials as part of the product finishing process. Other visual inspection processes will also be undertaken such as media simulation and lactose fills when required. The main responsibility of the role is within the visual inspection team however when time permits there will be opportunities to engage in other aspects within the production unit. The post holder will report to the Product Finishing Team Leader/supervisor.

The post holder will…

The visual inspection team performs the manual 100% visual inspection of Erwinase vials, a process which involves a visual assessment of final drug product vials and the removal of rejected material from the batch. Full training will be provided and once qualified you will work together as part of the team to undertake the visual inspection of all Erwinase batches manufactured. This activity will take up the majority of the time however there are opportunities between inspections to work alongside other production operators and become trained in other processes within the Production unit.

We are looking for…

The post holder will have a good general education and be educated to a minimum of NVQ 2 level in a relevant subject or equivalent level of qualification or significant equivalent proven experience as well as holding a GCSE in Mathematics, English & Science. The nature of this post requires individuals who can remain diligent and focused throughout the day. Candidates will have experience of working to deadlines, schedules and the ability to follow written procedures. Candidates need to have excellent attention to detail, be a good communicator and be able to work effectively as part of a team.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL498 Validation Technologist (Facilities & Utility)

Salary: Starting Salary £29,335 negotiable dependent upon experience.

Reference Number: PBL498

Job Purpose…

The Facilities Validation department supports cGMP manufacturing activities and is responsible for ensuring compliance to the cGMP guidelines on Validation activities.

The purpose of this role is to execute validation activities relating to Facilities and Utilities. This will involve coordination with Engineering, Production, QC and QA departments to ensure a timely delivery of the qualification report.

The post holder may be expected to supervise contractor resource where appropriate with responsibility to ensure adequate training and supervision is provided.

The post holder will be required to write, review and where appropriate approve validation reports prior to execution, followed by report generation. The core activities will include thermal and microbiological testing of:

  • Autoclaves (BSEN-285)
  • Depyrogenation ovens
  • Extraction Tanks
  • Centrifuges
  • Vessels
  • (but not limited to) the qualification of Facilities and Utilities.

The post holder will...

  • Generate, review (technical) and execute process validation protocols (thermal and microbiological testing)
  • Create Process validation reports
  • Use the Electronic Quality Management System (EQMS) to manage appropriate corrective action plans and report through the PBL non-conformance system, for failures/performance issues.
  • Write and review Risk assessments
  • Manage work schedule as planned by the validation schedule co-ordinator
  • Coordinate Contractor or permanent resources to deliver timely documentation in support of Process Validation activities
  • Ensure Process Validation procedures are aligned with regulatory requirements
  • Meet all internal regulatory training requirements (internal training provided)

We are looking for...

A person with at least 12 months hands-on validation experience, able to perform thermal mapping studies and write protocols and reports. A sound knowledge of the Validation Life cycle and documentation deliverables is an essential requirement.

Other
In addition to Utilities and Sterilisation validation activities the post holder will be expected to undertake any related validation activities deemed necessary by line management. This could include the generation of validation documentation in accordance with the full validation life cycle for equipment, utilities and facilities.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL512 Process Validation Specialist

Salary: circa £40,000 per annum, negotiable dependant on experience

Reference Number: PBL512

Job Summary…

This role of the Process Validation Specialist is to coordinate the execution of Performance Qualification and Process Performance Qualification activities in support of PBL manufacturing activities and in accordance with Regulatory requirements.

The post holder will…

Have knowledge of Validation Life Cycle documentation deliverables and how to implement a Risk based approach is central to the skills base of this position.

The role will include the writing, review and execution of Process Validation plans, protocols and reports and the coordination of support activities to deliver on time a high standard of documentation.

The candidate will have a degree in Science or Engineering or equivalent and recognised academic achievement and have Project Management experience.

We are looking for…

The post holder will be expected to attend Project group meetings, liaise with PBL support teams, regulatory bodies and peers to establish data for inclusion into protocols and reports.

The position holder should be prepared to execute and witness Process Validation studies in line with the production schedule.

The following is a description of the main duties and responsibilities;

  • To coordinate the execution of the Validation Master Plan with respect to Process Validation activities.
  • Assess Change control documentation to determine change impact with respect to the validation requirements and report appropriately.
  • To support operational areas in the implementation of change.
  • Supports Process Validation activities.
  • Define Process Validation Strategies in conjunction with the Process Validation Lead
  • Author and review Process Validation plans, protocols and reports ensuring compliance to PBL policies and procedures.
  • Schedule and support Process Validation executions.
  • High level of technical and scientific writing required.
  • Understand and Applies statistical tools for development of protocols and data analysis for Process Validation (as per current FDA/MHRA Process validation lifecycle guidelines). Participate in Continued Process Verification Activities (CPV) including the generation of CPV plans and CPV reporting.
  • Present Process Validation documents at regulatory audits.
  • Performs process investigations with relevant departments as required.
  • Performs product and process impact assessments.
  • Participates in or Lead process and quality risk assessments.
  • Presents findings at group and at interdepartmental meetings.
  • Communicate information on current process data which may impact Process Validation.
  • Maintain and review the Product Control Strategy for all products. Understand the functional relationships that link CMA/CPP to CQA.
  • To ensure the timely completion of Deviations and the closure of CAPAs

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd to recruitment@portonbiopharma.com

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL522 Senior Production Technician - FPP

Salary: Starting salary £21,000 per annum, plus 30% shift enhancement

Reference Number: PBL522

Job Purpose…

This is a shift working role which will attract a salary enhancement once appointed. This Senior Production Technician post is located at Porton Down in the Fermentation Process Plant (FPP) current Good Manufacturing Practice (cGMP) pharmaceutical manufacturing facility. This facility produces therapeutic products by bacterial fermentation followed by initial phase downstream processing.

Therapeutic products produced at Porton are licensed and marketed for worldwide distribution. The FPP is undergoing significant investment and expansion as production is being increased to meet product demand.

We are looking for…

An applicant who has GCSE’s in Maths, English and Science or equivalent qualifications. In addition, they should also be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. Candidates should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. They should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

The post holder will…

Work a shift pattern which covers 24-hour, 7 day working. They will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be provided.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information about the post, please contact: recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL527 Unit Manager PPC

Salary: Circa £29000.00 - £43000.00 per annum, negotiable dependant on experience

Reference Number: PBL527

Job Summary………………..

 Unit Managers are located at various manufacturing centres at Porton Down. The facility is an FDA and MHRA licensed GMP manufacturing facility which produces therapeutic products using various chemical and natural techniques.

The post holder will…………

 Manage and supervise the output of a small team in a high-pressure manufacturing environment.

Work in a highly regulated pharmaceutical manufacturing area.

Ensure that the various work areas are maintained at the highest state of readiness at all times.

Ensure that the daily activities of staff are coordinated with other team members.

Work within a GMP quality system.

Ensure that documentation is completed within the legal frameworks.

Take responsibility for Non- Conformances, CAPA, Risk Assessments and Change Controls for the area and ensure SOPs and BMRs are available for use.

We are looking for……………….

 The successful candidate will be self-motivated, well organised and have been educated to degree level or equivalent. Previous experience managing a small team is essential. The candidate will be part of a team responsible for a series of tasks in a number of different areas.

For further information or an informal discussion about the post, please contact:

Brian Lumby Deputy Head of Production by email brian.lumby@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL538 Data Integrity & Continous Improvement Manager

Salary: Circa £50,000. depending on experience

Closing Date: 11th October 2019

Reference Number: PBL538

Job Purpose / Summary

 To lead, motivate and manage multidisciplinary teams with the responsibility for delivery and maintenance of audit, supplier management and training.

  • To develop, lead & maintain PBLs Quality Continuous Improvement programme in accordance with regulatory and business requirements
  • To review and monitor the effectiveness of PBLs data integrity system and to manage the implementation of improvements as required to address any detected deficiencies.
  • Lead the development and implementation of an ongoing Quality Improvement plan to maximise efficiency of the Quality System process and to improve compliance.
  • Ensure the audit, supplier management and training systems meet the needs of the business and quality system and regulatory requirements.
  • Monitor KPI’s and identify and implement improvements as appropriate.

 The post holder will

 The successful candidate will have a degree or equivalent in a relevant subject (e.g. Science), significant experience of management of multidisciplinary teams delivering a variety of services & projects. The candidate will have experience of dealing with internal customers, negotiating and agreeing work programs, reporting progress, dealing with issues to ensure delivery and customer satisfaction.

The successful candidate will have significant experience of Quality Assurance with a GXP environment and a working knowledge of lean manufacturing and continuous improvement. The successful candidate will also have been responsible for implementing Data Integrity controls within a GMP environment.

We are looking for

 An applicant with excellent communication skills who is experienced in the management of multidisciplinary teams delivering a variety of services & projects. Practical experience of Continuous Improvement and understanding of GMP Data Integrity requirements is essential.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

To download the job description please click here