Careers

Porton Biopharma has approximately 350 staff in a wide range of roles from those working in our pharmaceutical manufacturing plants, through to our quality and scientific development groups.  All focused on developing & manufacturing life-saving products that make a real difference to patients’ lives.

We are always looking for people, ranging from those with a general interest in science & technology, to ones with higher qualifications and/or experience.

This currently includes various vacancies for pharmaceutical production staff and supervisors to support our continued growth.  So if you are a motivated person who is interested in working in a high-tech environment as part of a dynamic team, then there could be a role for you.

 

 

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WE OFFER…

A friendly environment working alongside committed teams of people, who will be happy to share their knowledge and experience to allow you to develop your potential, with benefits that include:

  • a competitive salary
  • the necessary training
  • a pension scheme
  • 30 days annual leave
  • a canteen, gym and an active sports & social club
  • free on-site parking

With ongoing investment into the company and plans to increase our workforce, we are committed to being a leading life-science company that really makes a difference to patients’ lives.

To see the sort of  people that we ‘re looking for, the  Staff Profiles page has short interviews with current staff giving an overview of just some of our roles.

CURRENT VACANCIES…

PBL only accept CV’s from Recruitment Agencies with whom we have agreed Terms & Conditions.

A list of our current vacancies shown below.

To apply for a specific vacancy applicants should  send a covering letter quoting the Job Reference Number, a copy of their CV, together with a supporting statement referring to both the Job Description and Person Specification.

However, we also welcome applications from people with transferable skills that are looking for that next challenge and to develop their career.  To be considered for up-and-coming roles please send a covering letter indicating why you want to join PBL and in which area your career aspirations lie (Engineering  / Production  / Quality etc.),  along with a CV detailing your skills and experience which we can keep on file for when a suitable position becomes available.

All applications should be sent to recruitment@portonbiopharma.com.

WORK EXPERIENCE

As a business, we recognise the value that offering work-experience placements can bring and typically offer up to 4  one-week placements each year, usually in June.   All applicants must be over 16 years of age at the time of the placement, and will be chosen following a selection process.

If you are interested in applying, then send an email and covering letter stating your interest and giving reasons why we should choose you to business@portonbiopharma.com  Applications must be received by the end of November in order to be considered for the following summer’s places.

 

PBL407 Process Engineer

Salary: £29,355 negotiable dependent upon experience

Reference Number: PBL407

Job Summary…

The Engineering group provides all engineering support within the highly regulated GMP production facilities at PBL Porton Down. The group includes engineering functions provided by predominantly chartered professional engineers specialising in clean rooms, GMP critical utilities, production equipment, pharmaceutical facilities, and capital works delivery.

The Process Engineer is the System technical expert for all Process and Utility systems within the GMP Envelope and is responsible for identification of and managing small projects/initiatives relating to these systems and interfacing with the wider Engineering group to ensure equipment systems within the GMP envelope remain compliant with current Good Manufacturing Practice. In addition, the Process Engineer will work within an Integrated Process Team to provide operational support to the manufacture of biopharmaceutical products.

The post holder will…

Be a core member of an Integrated Process Team and will provide operational engineering support to the manufacture of biopharmaceutical products alongside other core members from the Production and Quality functions. You will have delegated responsibility from the Process Engineering Manager to design, manage and deliver process improvement projects and represent the group in the delivery of major facility expansion/refurbishment projects.

You will become the Subject Matter Expert for a variety of systems and equipment such as Autoclaves and Critical Utilities (e.g. WFI, Clean Steam, and Purified Water) within the Pharmaceutical Production Envelope. As such you will interface with key stakeholders including equipment users, capital project managers, and the site principal maintenance contractor, to ensure these critical systems remain in compliance with best industry and regulatory practice.

We are looking for…

An applicant with experience of design or operation of process or utility systems in a highly regulated industry. The ideal candidate will have existing experience in the pharmaceutical industry. The individual will be either working towards or have recently become chartered with a supporting process or chemical engineering degree.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL411 Aseptic Processing Specialist

Salary: Starting salary £29,355 negotiable dependent upon experience

Reference Number: PBL411

Job Purpose…

This position will report to the Aseptic Processing Functional Manager and will provide technical specialist support to all aseptic processing activities in the manufacture of Erwinase, Anthrax vaccine and other PBL products. The role will work cross functionally and be involved in current projects, new projects and all manufacturing activities that require aseptic processing input. It is expected that the role will typically focus on day to day aseptic processing matters within Production but may also be required to support projects designed to improve and develop PBL’s aseptic processing strategy.

We are looking for…

An individual who is educated to degree level or equivalent in a relevant discipline. The successful candidate should have a minimum of 5 years’ experience within Biopharma / Pharma aseptic GMP environments and have an in depth understanding of aseptic processing and techniques. You will need to have an understanding of regulatory requirements for biological products and experience in the implementation of new technologies and equipment into GMP manufacture and will have proven experience of generating GMP documents within a quality system. Experience of delivering specialised technical training and report writing and data trending evaluation would be desirable but not essential. The successful applicant will have a flexible approach to work and be able to deliver to schedules.

The post holder will…

  • Lead in the day to day aseptic processing of PPL’s products.
  • Support the management and development of improved and new processing techniques in the various aseptic processing activities.
  • Provide technical support to production staff involved in the various aseptic processes.
  • Provide troubleshooting and technical support into process investigations.
  • Collate and share technical information with internal and external bodies to benefit the production methods, teams and departments.
  • Perform process mapping and process efficiency trending.
  • Provide specialist training to staff in aseptic processing techniques and theory.
  • Identify, evaluate and adapt new technologies where appropriate and ensure that the production area operates to a high standard and complies with GMP and other regulatory standards.
  • Assist colleagues in providing technical specialist input as required, in developing production and technical strategies for the units, identifying new opportunities as they arise and responding to external queries and complaints.
  • Contribute to reports and assist on the preparation of presentations, publications and liaison with customers, collaborators and licensing agencies.
  • Support the Functional Manager Aseptic Processing in pursuance of strategic improvements to aseptic processing control.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL442 Computer System Validation Specialist

Salary: Starting salary £42,230 negotiable dependent upon experience

Reference Number: PBL442

Job Purpose

This role is within the Facilities Validation Department and is responsible for the provision of subject matter expertise and the execution of Computerised System Validation activities.The Facilities Validation department supports cGMP manufacturing activities and is responsible for ensuring compliance to the cGMP guidelines.

This role reports into the Computer Systems Validation Manager and is responsible for the timely execution of Computer Systems Validation activities with respect to:

  • Writing (and reviewing) of validation protocols
  • Timely execution of CSV protocols with the subsequent generation of reports
  • Leading CSV compliance investigations with respect to Non-conformances and CAPAs
  • Performing CSV / Data integrity gap analysis and remediation activities.

The post holder will be expected to write, review and approve validation protocols, execute validation studies and write, approve validation reports associated with the qualification of Computerised systems and the introduction of new equipment into beneficial use.

The post holder will…

  • Take the lead in computer system validation and compliance, manage and deliver specific Validation Projects according to the business priorities, including work scheduling and supervision of junior members of staff.
  • Promote continuous improvement of validation systems and procedures to ensure efficiency and best practice within the industry and to stay abreast of changing regulatory expectations.
  • Write, review and approve validation documentation including protocols and reports and manage the timely closure of any discrepancies or non-conformities
  • Provide a reliable service to our internal customers to ensure that timescales are met, and work is carried out to meet expectations.
  • Maintain the ongoing compliant status of computer systems associated with equipment, facilities and utilities by involvement of the scheduling of activities.
  • Communicate validation activities with our internal and external customers and work with them to resolve problems and conflicts.
  • In line with overall responsibilities, perform additional tasks assigned by the line manager.
  • Undertake all work in accordance with Code of Safety Practice and site Quality Policies.

We are looking for…

The successful candidate will be educated to BTEC National Certificate level including Science or equivalent qualification or significant equivalent experience. A BSc in Engineering, Science or IT would be desirable but is not essential. You will need to have substantial experience of generation, execution and review of validation protocols, reports and technical documents as well as experience of validation life-cycle activities for computerised systems. The successful applicant will have extensive practical experience of working within a GMP quality system. Practical experience of working within a biopharmaceutical manufacturing environment would be desirable.

This is a hands-on role in a dynamic operating environment and the ideal candidate should be self-driven and capable of organising their own work-load. They should be comfortable liaising with stake-holders in order to deliver an effective documentation to an agreed time line and be confident to supervise junior staff.

For further information about the post, please contact: kevin.smart@portonbiopharma.com

To download the job description please click here

PBL485 QC Technologist (Monitoring and Training)

Salary: Starting salary £23,735 per annum negotiable dependent upon experience

Reference Number: PBL485

Job Purpose…

To provide specialist training in microbiological environmental monitoring methods, cleanroom gowning, aseptic practices and water sampling. The successful candidate will also be required to undertake microbiological environmental monitoring of critical pharmaceutical manufacturing operations to support the Sterility Assurance Program. To supervise, oversee, observe and qualify all production technologists and other staff where applicable, in gowning, microbiological environmental monitoring methods and water sampling.

We are looking for…

A candidate who has previous experience of working in cleanrooms, performing environmental monitoring and training of other members of staff to join the Environmental Monitoring Team within QC Biological Services. A degree in a relevant scientific discipline is desirable but not essential. The candidate should also have a good understanding of QC Microbiology laboratory testing. Applicants must have a flexible approach to working and be able to comply with SAPO regulations and must have a current valid right to work in the UK.

The post holder will…

  • Operate in compliance with cGMP.
  • Train and qualify all Production and other staff, as necessary, in the techniques and procedures for microbiological environmental monitoring.
  • Train and qualify all Production and other staff, as necessary, in water sampling.
  • Train and qualify all Production and other staff, as necessary, in procedures for gowning.
  • Oversee, supervise and observe Production and other staff undertaking environmental monitoring and water sampling to ensure continued compliance.
  • Re-qualify Production and other staff at a defined frequency, as required by GMP.
  • Plan and organise schedules for training, qualifications and observations.
  • Assess staff competence in environmental monitoring, water sampling and gowning procedures. Sign training documentation and produce certificates for trained members of staff.
  • Carry out and record microbiological environmental monitoring for critical manufacturing operations, and routine monitoring where required.
  • Input microbiological environmental monitoring and water sampling data into appropriate databases and spreadsheets.
  • Be involved in the writing and updating of Standard Operating Procedures relating to environmental monitoring and water sampling, either as the author, or by providing technical information and advice to the author.
  • Attend training courses that contribute to the efficiency of the operating systems and are beneficial to the post holder’s personal development.
  • Follow operating procedures at all times and ask for advice when necessary.
  • Undertake all work in accordance with Porton Down’s Code of Safety Practice and Quality Systems.
  • To prepare environmental summary reports of production processes for insertion into documents, reports and batch manufacturing records as part of batch release.
  • To investigate out-of-specification water and environmental monitoring test results in conjunction with the Compliance Team and review resulting Non-Conformances, participating in Ishikawa and 5-Whys investigations, where necessary.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL491 Visual Inspection Production Technician

Salary: Starting salary £20,220 per annum negotiable dependent upon experience

Reference Number: PBL491

Job Purpose…

This post is part of the Product Finishing team within PBL’s Pharmaceutical Production Unit which is responsible for duties including media and equipment preparation, assisting with purification and formulation of Erwinase Drug Substance, sterile filtration, and aseptic processing within a Good Manufacturing Process (GMP) department.

This post will involve training and qualification in the visual inspection process. Once qualified, the post will involve manual visual inspection of all Erwinase vials as part of the product finishing process. Other visual inspection processes will also be undertaken such as media simulation and lactose fills when required. The main responsibility of the role is within the visual inspection team however when time permits there will be opportunities to engage in other aspects within the production unit. The post holder will report to the Product Finishing Team Leader/supervisor.

The post holder will…

The visual inspection team performs the manual 100% visual inspection of Erwinase vials, a process which involves a visual assessment of final drug product vials and the removal of rejected material from the batch. Full training will be provided and once qualified you will work together as part of the team to undertake the visual inspection of all Erwinase batches manufactured. This activity will take up the majority of the time however there are opportunities between inspections to work alongside other production operators and become trained in other processes within the Production unit.

We are looking for…

The post holder will have a good general education and be educated to a minimum of NVQ 2 level in a relevant subject or equivalent level of qualification or significant equivalent proven experience as well as holding a GCSE in Mathematics, English & Science. The nature of this post requires individuals who can remain diligent and focused throughout the day. Candidates will have experience of working to deadlines, schedules and the ability to follow written procedures. Candidates need to have excellent attention to detail, be a good communicator and be able to work effectively as part of a team.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL492 Senior Production Technician PPC

Salary: Cira £20,200, dependant on experience

Reference Number: PBL492

Job Purpose…

This post is located within Zones1-4 of the Pharmaceutical Production Centre (PPC). PPC Zones 1-4 is dedicated to the manufacture of Erwinase within two manufacturing sub units the Therapeutics Protein Unit (TPU) and Product Finishing Unit (PFU), both units are GMP manufacturing facilities. TPU performs downstream purification of the therapeutic products and PFU performs aseptic processing and final fill, freeze drying and visual inspection of the product. The team is responsible for the production of pharmaceutical products, preparation of components and the operation of production equipment. Day to day tasks also include maintaining the facility via specialist cleaning procedures, monitoring environmental conditions and performing aseptic processes within a cleanroom environment.

The post holder will…

Report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring activities supporting manufacturing are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment, to completion of Quality documentation. Full training will be provided where required.

We are looking for…

Applicants should have a GCSE in Maths, English and Science. They should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. Candidates should be able to communicate clearly, possessing good writing and data entry skills. Candidates will need to have a flexible approach to work, be able to work effectively as part of a team as well as being proactive and able to work on their own initiative.

For further information about the post, please contact:recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL 496 QC Stability Technician

Salary: Starting salary £20,220, negotiable dependent upon experience + 7% shift enhancement

Closing Date: 11th October 2019

Reference Number: PBL496

Job Purpose……

A crucial part of the pharmaceutical production process is undertaken by the Quality Control Department, which performs chemical and biochemical testing to ensure that the manufactured product is safe, efficacious and fit for patient use as a pharmaceutical material. To provide support for the chemical and biochemical analyses performed by QC technologists within Analytical QC department to support the manufacture of Porton Biopharma’s licensed pharmaceutical products; as required by EU Directive 91/356/EEC for GMP compliance.

The testing of in process and finished product samples, to defined specifications, while ensuring that work performed within the laboratories is carried out in accordance with the statutory requirements of current GMP and corporate statutory health and safety requirements.

The post holder will be required to work shift rotation. This rotation includes 2 weeks out of 8 weeks where the shift is 2-10pm and potential weekend working (schedule dependent).

We are looking for…

A full time, 12 month fixed term contract for QC Stability Technician to perform analyses within the QC department of our pharmaceutical manufacturing facilities. The ideal candidate will have 2 A levels in numerate or Science subjects as a minimum.

The successful candidate will have working knowledge or experience within a regulated or cGMP environment. Experience in setting up stability studies, writing stability protocols and reports. Other key skills include the ability to work to deadlines, technical report writing, problem solving, the ability to work as part of a project team and good computer literacy.

 The post holder will…

  • Completion of QC forms and associated paperwork
  • Sample delivery between the stability department and the QC laboratories
  • Data entry into Excel spreadsheets and other databases
  • Order consumables and chemicals for the laboratories
  • Archive old documents
  • Competition of Good Manufacturing Practice (GMP) paperwork
  • The collection and distribution of GxP documentation for QC
  • To ensure documentation (SOP’s, Specifications, Monographs, MSDS’s etc) within the department are current and copies are available
  • To maintain accurate records and filing systems
  • Ability to follow all Standard Operating Procedures (SOP’s)
  • Assist with housekeeping in Analytical QC
  • Disposal of toxic, hazardous and non-hazardous waste generated within Analytical QC
  • Calibration and scheduled maintenance of Analytical equipment
  • Maintain stock lists in QC Stability

For further information about the post, please contact:recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL498 Validation Technologist (Facilities & Utility)

Salary: Starting Salary £29,335 negotiable dependent upon experience.

Reference Number: PBL498

Job Purpose…

The Facilities Validation department supports cGMP manufacturing activities and is responsible for ensuring compliance to the cGMP guidelines on Validation activities.

The purpose of this role is to execute validation activities relating to Facilities and Utilities. This will involve coordination with Engineering, Production, QC and QA departments to ensure a timely delivery of the qualification report.

The post holder may be expected to supervise contractor resource where appropriate with responsibility to ensure adequate training and supervision is provided.

The post holder will be required to write, review and where appropriate approve validation reports prior to execution, followed by report generation. The core activities will include thermal and microbiological testing of:

  • Autoclaves (BSEN-285)
  • Depyrogenation ovens
  • Extraction Tanks
  • Centrifuges
  • Vessels
  • (but not limited to) the qualification of Facilities and Utilities.

The post holder will...

  • Generate, review (technical) and execute process validation protocols (thermal and microbiological testing)
  • Create Process validation reports
  • Use the Electronic Quality Management System (EQMS) to manage appropriate corrective action plans and report through the PBL non-conformance system, for failures/performance issues.
  • Write and review Risk assessments
  • Manage work schedule as planned by the validation schedule co-ordinator
  • Coordinate Contractor or permanent resources to deliver timely documentation in support of Process Validation activities
  • Ensure Process Validation procedures are aligned with regulatory requirements
  • Meet all internal regulatory training requirements (internal training provided)

We are looking for...

A person with at least 12 months hands-on validation experience, able to perform thermal mapping studies and write protocols and reports. A sound knowledge of the Validation Life cycle and documentation deliverables is an essential requirement.

Other
In addition to Utilities and Sterilisation validation activities the post holder will be expected to undertake any related validation activities deemed necessary by line management. This could include the generation of validation documentation in accordance with the full validation life cycle for equipment, utilities and facilities.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL505 Unit Supervisor

Salary: Starting salary £22,660 negotiable dependent upon experience

Reference Number: PBL505

Job Purpose…

The post is located within the Product Finishing Unit (PFU). PFU is a GMP manufacturing facility focused on the filling, freeze drying and visual inspection of pharmaceutical products. Working in a highly regulated environment, you’ll be supervising a small team working in the production of pharmaceutical products or the operation of production equipment used in the preparation of components.

The post holder will…

The post holder will report to and support the Team Leader by supervising manufacturing operations and ensuring they are performed in a timely and compliant manner to cGMP requirements. This role will involve supervising a team of technicians while they undertake a range of tasks, from preparation and use of operational equipment to preparation and completion of Quality documentation. Full training will be provided where required.

Main duties include but are not limited to:

  • Carry out duties involved in the manufacture of biopharmaceuticals to GMP and ISO 9001 requirements as directed.
  • Ensure that the facility is maintained in a compliant state and that the product/materials are manufactured to appropriate regulatory requirements.
  • Responsible for the provision of all consumables, supplies, etc. required for the process and documented storage of materials generated.
  • Manage and support junior staff in all their activities and ensure they are adequately trained in all operational processes.
  • Responsible for ensuring that all staff adhere to, and all operations are carried out to, strict GMP guidelines.
  • To undertake all necessary training to enable the post holder to carry out his/her duties to the required standard.
  • Assist the Unit Manager/Team Leader in the completion of annual and six-monthly staff appraisals.
  • Generate and review documentation with regard to risk assessments and cGMP, e.g. SOPs, to ensure compliance of the Unit with all necessary regulations. Complete documentation and records accurately and to a high standard.
  • To assist in the timely closure of non-conformances, CAPAs and change controls.
  • Work accurately with good hand and eye co-ordination, sometimes for prolonged periods of time.
  • Required to work extended hours on critical processing days.
  • Perform a wide range of routine and some non-routine technical procedures and understand the rationale behind the procedures and practices.
  • To undertake work in accordance with PBL Health and Safety Policies and procedures and to work within any Quality systems that are appropriate to the site.

 

We are looking for…

 Applicants should be educated to an HNC level (or equivalent) or have significant equivalent GMP production experience. They should also have significant experience in a relevant technical area and a good working knowledge of cGMP requirements and how to implement them in the workplace. Candidates should be able to communicate clearly and possess good writing and data entry skills and have well-developed problem-solving skills and the ability to respond to sudden unexpected demands. Lastly applicants should have a flexible approach to work, be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL507 QC Analytical Laboratory Manager

Salary: Circa £36000.00 per annum

Reference Number: PBL507

Job Summary

To lead and manage a specialist GMP analytical chemistry/biochemistry laboratory to provide compliant testing of licensed pharmaceutical products; plus validation of analytical methods and expert support and advice to GMP product teams. This position will lead approximately 8 staff consisting of Senior QC Analyst, QC Analysts and QC Technicians performing essential analysis on Biopharmaceutical products including release, in-process and stability testing. This post will manage the product testing team within quality control performing a wide range of analytical testing on biopharmaceutical products.

We are looking for

A motivated individual who is experienced in leading a team and has extensive knowledge of analytical techniques. The successful candidate will be experienced in using quality management systems in the pharmaceutical industry and will be able to work to tight deadlines.

 To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL508 QC Technologist (Waters)

Salary: Starting salary £22,660 negotiable dependent upon experience plus 7% shift enhancement

Reference Number: PBL508

Job Purpose…

A crucial part of the pharmaceutical production process is undertaken by the Quality Control Department, which performs chemical and biochemical testing to ensure that the manufactured product is safe, efficacious and fit for patient use as a pharmaceutical material. The QC Technologist is primarily responsible for testing of in process and finished product samples, to defined specifications while ensuring that work performed within the laboratories is carried out in accordance with the statutory requirements of current GMP and corporate statutory health and safety requirements. The QC Technologist is also responsible for the authoring of technical documentation and liaising with external laboratories to arrange contract testing of products.

The post holder will be required to work shift rotation. This rotation includes 2 weeks out of 8 weeks where the shift is 2-10pm and potential weekend working (schedule dependent).

The post holder will…

  • Ensure analysis and recording of QC and stability testing is performed in compliance with the statutory requirements of cGMP.
  • Be responsible for testing in process and finished product samples to ensure that they meet the specifications established in the product licence and internal Porton Biopharma specification documents.
  • Be responsible for writing Standard Operating Procedures and their associated risk assessments to ensure that those tasks are performed safely, and other quality documents e.g. change controls, validation reports, non-conformances and CAPAs where appropriate.
  • Organise and liaise with external testing laboratories to arrange correct and on time testing to meet production deadlines or suppliers of equipment or chemicals.
  • Organise and liaise with internal departments such as validation, pharms stores and QA where required.
  • Maintain an up-to-date awareness of regulatory and scientific developments via courses, meetings and literature.
  • Undertake work in accordance with Porton Biopharma’s Code of Safety Practice and Quality Systems.
  • Maintain training records.
  • Cleaning of laboratories.
  • Performing maintenance and calibration of equipment.

We are looking for…

The ideal candidate will be educated to degree level or equivalent qualification in Chemistry, Biochemistry or other related subject. The successful candidate will have working knowledge or experience within a regulated or Good Manufacturing Practice (GMP) environment. Experience in biopharmaceutical analysis and analytical chemistry is desirable in one of the following areas; Water analysis, TOC, physical testing, UV-Vis or pharmacopoeia testing within a GMP compliant QC laboratory. Other key skills include the ability to work to deadlines, technical report writing, problem solving, the ability to work as part of a project team and good computer literacy.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL511 Production Technician

Salary: Cira £20,200, dependant on experience

Reference Number: PBL511

Job Summary...

The position is in the Immuno team who produce Anthrax Vaccine. The successful applicant will be responsible for manufacturing Anthrax Vaccine to cGMP standards as well as standard housekeeping tasks to keep the unit compliant

 The post holder will...

  • Perform a range of routine Production and some non-routine technical procedures and understand the rationale behind the procedures and practices.
  • Undertake all work in accordance with PBL’s Code of Safety Practice, Quality System and all other regulatory requirements.
  • Follow defined procedures, policies, rules, regulations and guidelines for all activities to ensure product meets the required standard.
  • Generate and review documentation with regard to Risk Assessments and cGMP to ensure compliance of the unit with all necessary regulations.
  • Work diligently at all times. Complete documentation and records accurately and to a high standard.
  • Ensure the unit is maintained in a compliant state. Work to cGMP following Standard Operating Procedures (SOPs) and Codes of Practice. Keep updated on new rules and regulations.
  • Perform and record environmental monitoring and water sampling in cGMP areas in accordance with documented procedures. Monitor and record air pressures and hot and cold facility temperatures.
  • Analyse information and make decisions based on assessment.
  • Assist validation department with validation protocols on equipment.
  • Maintain and use a variety of laboratory equipment.
  • Work with a range of hazardous and non-hazardous chemicals.
  • Be competent in and perform aseptic techniques.
  • Be qualified to work in a clean room environment and in containment level 3 suites.
  • Work accurately and with good hand eye co-ordination, sometimes for prolonged periods of time.
  • Operate autoclaves and sterilising ovens and have an appropriate level of understanding to review cycle data as a senior operator.

We are looking for…

A well organised person with good documentation skills and work ethic. Previous GMP experience will be beneficial but not essential as training will be provided.

For further information or an informal discussion about the post, please contact:

Graham Douglas on 01980 557102 or graham.douglas@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd to recruitment@portonbiopharma.com

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL517 Electrical Maintenance Technician

Salary: Circa £32,000 per annum, negotiable dependant upon experience

Reference Number: PBL517

Job Summary…

The Engineering group is responsible for provision of all engineering support within the highly regulated GMP Facilities at Porton Biopharma Ltd (PBL). This structure includes engineering functions provided by professional engineers specialising in clean rooms, GMP critical utilities, production equipment, pharmaceutical facilities and capital works delivery. Being based on the Main Site you will be an integral part of a multi skilled maintenance team that support PBL’s equipment and utilities.

The main role of the Electrical Maintenance Technician is to perform installation and maintenance of PBL equipment and utilities. This role involves interfacing with equipment/system owners, the principle maintenance contractor, capital project managers and the Quality Departments to ensure compliance is maintained with current Good Manufacturing Practice (GMP).

The post holder will…

Be working within the PBL Engineering team you will undertake all aspects of electrical maintenance both planned and reactive on process equipment, plant and clean steam, purified water and effluent systems. Tasks to be undertaken will be varied from full annual servicing to routine daily checks of PBL equipment and utilities. Working as part of a multi-skilled team you will also be required to troubleshoot breakdowns.

With support you will be ensuring all PBL equipment and utilities are maintained at all times, you will become a valued member of the GMP engineering team working to minimize disruption to manufacturing activities.

We are looking for…

A candidate with 18th Edition qualification and ideally experience and knowledge of mechanical maintenance. The candidate must also be familiar with Engineering H&S Legislation and an NVQ in a mechanical subject or equivalent qualification would be desirable but not essential. The successful candidate will need to have excellent organisational skills and have proven experience in fault investigation.

For further information or an informal discussion about the post, please contact: stuart.naylor@portonbiopharma.com

We reserve the right to close this role once a suitable candidate has been found.

To download the job description please click here

PBL542 QC Microbiology Compliance Officer

Salary: Circa £25,000 per annum

Job Purpose / Summary

The purpose of this role is to provide support for the QC Microbiology department at Porton Biopharma. This will include compilation of compliance documentation, including deviations, non-conformances and CAPA, change controls, protocols and reports. The holder will also to undertake and perform microbiological QC analyses in compliance with cGMP.

The post holder will…………

  • Write and review Standard Operating Procedures, protocols and reports in accordance with regulatory requirements.
  • Investigate, write and review non-conformances and deviations raised in accordance with regulatory requirements.
  • Complete departmental CAPAs and to implement any required quality improvements that may arise from this.
  • Identify and implement quality improvements within the department pro-actively.
  • Carry out change management, raising, writing and reviewing change controls.
  • Assist as a member of the QC Microbiology Team, on a day to day basis, of the Bacteriology Technical Services Unit.
  • Test microbiological samples, working at ACDP Containment level 2 and at Containment Level 3, when required, from all stages of the production processes of products manufactured at PBL, Porton Down and to assess the results against pre-set standards.
  • Record and assess results from environmental and water sampling and carry out preliminary and confirmatory identification of micro-organisms.

 We are looking for……………….

A candidate with significant experience of working to cGMP, with a significant knowledge of pharmaceutical Quality Assurance. The candidate must have experience in writing and reviewing discrepancies, procedures, change controls and CAPAs. The candidate should have a significant level of experience of working within ACDP containment level 2 microbiology laboratories.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL543 QC Technologist

Salary: £23735.00 per annum

Closing Date: 18th October 2019

Reference Number: PBL543

Job Summary ….

The Biological Technical Services Group within Quality Control at Porton Down provides a specialist ACDP level 2 and 3 containment testing service. Both microbiological and bioassay testing is performed for products manufactured by the production and product development groups.

The post holder will ...

The post holder will perform testing using a range of specialist microbiological assays for the testing pharmaceutical products. The post holder will be required to train team members, assist in development projects and maintain the highest standards of data integrity.

 We are looking for…

 Applicants should have a HND or equivalent in Science. Candidates should be able to communicate clearly, possessing good writing and data entry skills. Candidates will need to have a flexible approach to work, be able to work effectively as part of a team as well as being proactive and able to work on their own initiative.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL541 Compliance Officer

Salary: Circa £27,000 per annum, dependant on experience

Closing Date: 25th October 2019

Reference Number: PBL541

Job Summary…

The position will work within a multi-functional/ multi-disciplinary team. Being the first QA point of contact for issues and resolution for quality matters. This role will be situated within departments across the business and will allow you to demonstrate your problem-solving skills as well as your ability to respond and adapt to various situations using risk management.

 We are looking for…

 An individual who is educated to at least degree level in a relevant subject (microbiology/ biotechnology) or equivalent qualification/ experience. They will have significant experience in Pharmaceutical Quality Assurance, as well as practical experience in:

  • Change Management
  • Risk Management
  • Non-Conformance
    • Batch Release
    • QA oversight across business

The post holder will…

Have excellent communication skills as well as being able to assess situations and take appropriate action. They will have resilience and determination to succeed in delivering work within strict timescales to ensure delivery of the product to patients.

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

 

To download the job description please click here

PBL537 Cleaning Validation Technologist

Salary: Circa £35,000 negotiable dependant on experience.

Closing Date: 25th October 2019

Reference Number: PBL537

Job Summary...

The Cleaning Validation team within the Validation Department supports the development and validation/qualification of manufacturing equipment cleaning processes. This includes both the validation of new or amended cleaning processes, and the ongoing routine cleaning verification of existing and validated cleaning processes.

This role is to execute the timely completion of cleaning validation studies in support of PBL manufacturing activities and regulatory requirements. The role will include the writing, review and execution of cleaning validation/verification protocol documents and reports, the coordination of support activities and resources to deliver on time a high standard of documentation.

The position holder will be expected to attend project group meetings, liaise with PBL support teams and peers to establish data for inclusion within protocols and reports.

The position holder should be prepared to execute and witness cleaning validation/verification studies in line with the Production schedule.

There will be a requirement to support other validation activities (e.g. Process Validation) on a temporary basis.

 The post holder will...

  • Write, review and execute cleaning validation/verification protocol documents.
  • Write cleaning validation/verification reports, where required.
  • Write, review and execute cleaning development documentation.
  • Deliver assigned cleaning development, validation and verification activities on time in accordance with the Site Validation Master Plan (VMP).
  • To deliver on non-conformance, action item, change control (CC) and CC actions on time.
  • Participate in assigned GEMBA meetings/activities, as required

We are looking for...

An enthusiastic candidate who can communicate effectively at all levels, and across multi-disciplinary teams, to support the completion of cleaning validation and cleaning verification activities to satisfy compliance and regulatory commitments, in addition to the continuous improvement of equipment cleaning processes at PBL.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

 

To download the job description please click here

PBL539 QC Microbiology Technologist

Salary: Circa £23,500

Reference Number: PBL539

Job Purpose…

The post holder will be part of the QC Bacteriology Technical Services team and assist with activities which include the following:

To undertake and perform microbiological QC analyses in the Quality Control Bacteriology Technical Services Unit, which provides specialist microbiological testing services in support of licensed pharmaceutical manufacture at PBL, Porton Down, in compliance with cGMP.

The post holder will…

  • Undertake and perform microbiological QC analyses in support of Porton Biopharma’s licensed production, service, validation and developmental programs
  • Carry out all work in compliance with cGMP
  • Test microbiological samples from all stages of the production processes of licensed and developmental products and to assess the results against pre-set standards and specifications
  • Undertake identification of micro-organisms isolated from microbiological tests and samples
  • Record all information and data clearly and accurately
  • Pre-test media used within QC and Production against pre-set specifications
  • Maintain the Bacteriology Technical Services Culture Collection, media stocks, and necessary consumables to ensure the efficient running of the group
  • Safely operate, clean and maintain laboratory equipment to the required levels of cleanliness and operating standards
  • Provide cover for and assist the Environmental Monitoring team when required

 We are looking for…

An applicant who has good interpersonal skills, is able to work as part of a team and is methodical and reliable with the ability to think clearly. The successful applicant will have the ability to learn and be able to respond to changes in schedule and demands. They will need to have knowledge and experience of microbiology gained in a laboratory or similar environment and ideally have experience of working in a Good Manufacturing Practice (GMP) or similarly regulated environment.

Key skills are:

  • Knowledge and experience of microbiology gained in a laboratory or similar environment
  • An understanding of GMP and quality systems
  • Able to work methodically and to strict deadlines
  • To perform routine testing within the microbiology laboratory, on a day to day basis, of the Bacteriology Technical Services Unit.
  • Good understanding of QC microbiological assays and QC laboratory systems
  • Confident to train junior staff in processes and procedures

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL544 Senior QC Technologist (Method Transfer) 18 month Fixed Term

Salary: Circa £29000.00 per annum

Closing Date: 1st November 2019

Reference Number: PBL544

Job Summary…

To manage and perform the transfer/validation of analytical methods from Development into a GMP environment in QC Analytical Services. The role involves all activities involved in transferring analytical methods from Development to QC Analytical Services including running analytical methods in both Development and QC Analytical Services, writing transfer/validation protocols, executing protocols in the laboratory, writing up the associated transfer/validation reports, performing release analysis and training existing members of staff in transferred methods.

We are looking for…

A motivated individual who will take on this exciting opportunity to transfer and validate a number of analytical techniques into a GMP environment. The successful candidate will have experience/knowledge of transferring and validating analytical methods in the pharmaceutical industry to the relevant guidelines (ICH, MHRA, FDA). Demonstrable experience of working to tight deadlines is essential and ideally the successful candidate will have some project management experience.

For further information or an informal discussion about the post, please contact:

QC Analytical Laboratory Manager, Dannii Hulme dannii.hulme@portonbiopharma.com or recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL545 Senior QC Technologist (Analytical)

Salary: Circa £29000.00 per annum, plus 7% shift allowance

Closing Date: 1st November 2019

Reference Number: PBL545

Job Summary…

To undertake and supervise chemical and biochemical analyses to support the manufacture of Porton Biopharma’s licensed pharmaceutical products; To supervise, schedule and verify work for QC Technologists. To write quality documentation relating product testing. To ensure that work performed within the laboratories is carried out in compliance with corporate statutory health and safety requirements.

The post holder will be required to work shift rotation. This rotation includes 2 weeks out of 8 weeks where the shift is 2-10pm and potential weekend working (schedule dependent).

The post holder will…

Supervise and run the day to day activities of the Product Testing team with Quality Control Analytical. Including Biochemical assays, enzyme kinetics and analysis as per the EP/USP. Completing investigations, laboratory improvements and training members of the team will also be a crucial part of the role.

 We are looking for…

A motivated individual to supervise a team of QC Technologists and Technicians. The successful candidate must have working knowledge / experience of cGMP in a laboratory environment and must have experience of standard laboratory equipment and methods. It is desirable to have knowledge and experience of enzyme analysis.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL546 QMS Documentation Controller & GxP Archivist

Salary: Circa £20200.00 to £26260.00 per annum

Closing Date: 1st November 2019

Reference Number: PBL546

Job Summary...

To assist with the daily operation of the Porton Biopharma Ltd. Documentation Control team

The post holder will...

Work with minimal supervision, to strict deadlines, methodically and to a high degree of accuracy to maintain records and filing systems to ensure adequate control of documents.

Performance of additional general office and administrative duties to support the activities of QA Groups e.g. filing, archiving, ordering supplies etc.The successful candidate will have 5 GCSEs or equivalent including English, Maths and a scientific subject. In addition, an RSA 3 in typing, word processing or a European Computer Driving License (ECDL) or equivalent would be beneficial.

Additional experience in an administrative role (general office work) and previous use of Computer based software systems, including the Microsoft Office suite and Windows based databases and spreadsheets would be an advantage.

We are looking for...

An applicant who has excellent communication skills in addition to good customer focus with a drive and determination to succeed in maintaining the current exceptional service levels. Using strong organisational and data entry skills the successful applicant will work within a small team to maintain a critical aspect of the site’s Quality Management System (Document Control and Archive Service).

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL512 Process Validation Specialist

Salary: circa £40,000 per annum, negotiable dependant on experience

Reference Number: PBL512

Job Summary…

This role of the Process Validation Specialist is to coordinate the execution of Performance Qualification and Process Performance Qualification activities in support of PBL manufacturing activities and in accordance with Regulatory requirements.

The post holder will…

Have knowledge of Validation Life Cycle documentation deliverables and how to implement a Risk based approach is central to the skills base of this position.

The role will include the writing, review and execution of Process Validation plans, protocols and reports and the coordination of support activities to deliver on time a high standard of documentation.

The candidate will have a degree in Science or Engineering or equivalent and recognised academic achievement and have Project Management experience.

We are looking for…

The post holder will be expected to attend Project group meetings, liaise with PBL support teams, regulatory bodies and peers to establish data for inclusion into protocols and reports.

The position holder should be prepared to execute and witness Process Validation studies in line with the production schedule.

The following is a description of the main duties and responsibilities;

  • To coordinate the execution of the Validation Master Plan with respect to Process Validation activities.
  • Assess Change control documentation to determine change impact with respect to the validation requirements and report appropriately.
  • To support operational areas in the implementation of change.
  • Supports Process Validation activities.
  • Define Process Validation Strategies in conjunction with the Process Validation Lead
  • Author and review Process Validation plans, protocols and reports ensuring compliance to PBL policies and procedures.
  • Schedule and support Process Validation executions.
  • High level of technical and scientific writing required.
  • Understand and Applies statistical tools for development of protocols and data analysis for Process Validation (as per current FDA/MHRA Process validation lifecycle guidelines). Participate in Continued Process Verification Activities (CPV) including the generation of CPV plans and CPV reporting.
  • Present Process Validation documents at regulatory audits.
  • Performs process investigations with relevant departments as required.
  • Performs product and process impact assessments.
  • Participates in or Lead process and quality risk assessments.
  • Presents findings at group and at interdepartmental meetings.
  • Communicate information on current process data which may impact Process Validation.
  • Maintain and review the Product Control Strategy for all products. Understand the functional relationships that link CMA/CPP to CQA.
  • To ensure the timely completion of Deviations and the closure of CAPAs

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd to recruitment@portonbiopharma.com

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL522 Senior Production Technician - FPP

Salary: Starting salary £21,000 per annum, plus 30% shift enhancement

Reference Number: PBL522

Job Purpose…

This is a shift working role which will attract a salary enhancement once appointed. This Senior Production Technician post is located at Porton Down in the Fermentation Process Plant (FPP) current Good Manufacturing Practice (cGMP) pharmaceutical manufacturing facility. This facility produces therapeutic products by bacterial fermentation followed by initial phase downstream processing.

Therapeutic products produced at Porton are licensed and marketed for worldwide distribution. The FPP is undergoing significant investment and expansion as production is being increased to meet product demand.

We are looking for…

An applicant who has GCSE’s in Maths, English and Science or equivalent qualifications. In addition, they should also be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. Candidates should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. They should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

The post holder will…

Work a shift pattern which covers 24-hour, 7 day working. They will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be provided.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information about the post, please contact: recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL527 Unit Manager PPC

Salary: Circa £29000.00 - £43000.00 per annum, negotiable dependant on experience

Reference Number: PBL527

Job Summary………………..

 Unit Managers are located at various manufacturing centres at Porton Down. The facility is an FDA and MHRA licensed GMP manufacturing facility which produces therapeutic products using various chemical and natural techniques.

The post holder will…………

 Manage and supervise the output of a small team in a high-pressure manufacturing environment.

Work in a highly regulated pharmaceutical manufacturing area.

Ensure that the various work areas are maintained at the highest state of readiness at all times.

Ensure that the daily activities of staff are coordinated with other team members.

Work within a GMP quality system.

Ensure that documentation is completed within the legal frameworks.

Take responsibility for Non- Conformances, CAPA, Risk Assessments and Change Controls for the area and ensure SOPs and BMRs are available for use.

We are looking for……………….

 The successful candidate will be self-motivated, well organised and have been educated to degree level or equivalent. Previous experience managing a small team is essential. The candidate will be part of a team responsible for a series of tasks in a number of different areas.

For further information or an informal discussion about the post, please contact:

Brian Lumby Deputy Head of Production by email brian.lumby@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL521 Fermentation Scientist

Salary: Starting salary £25,000 – £30,000 per annum, negotiable based on experience

Closing Date: 1st November 2019

Reference Number: PBL521

Job Purpose

The Development is a part of Porton Biopharma and is a development and technology transfer group playing a key role in the translational research activities of the site, developing manufacturing processes and associated analytical methods for use in the cGMP production of biotherapeutics and healthcare interventions. The projects may comprise of the development of research designs and/or the improvement of existing commercial processes.

The post-holder will contribute to the income generating activities of the Upstream Process Development Team by providing technical support in the development of production processes for biopharmaceutical products.

The post holder will

Provide scientific and technical specialism in the area of Upstream Process Development to the projects involved in the research and development of new products and improvement to the existing biopharmaceutical products. They will be required to work in multi-disciplinary teams to deliver key objectives. They will contribute to the generation of experimental designs, performing experimental work, presentation of work to the customers and the preparation of scientific publications, technical reports and project proposals. The post holder will contribute to process validation and manufacture problem solving activities and technology transfer activities relating to the development and/or manufacture of biopharmaceutical products internally or between Porton Biopharma and its collaborators/customers.

The post holder will be responsible for training staff within the area of specialism and supervising laboratories ensuring that work is undertaken to Porton Biopharma quality and safety policies. When required, they will work to the requirements of European and US cGMP. Additionally, the post holder will be required to maintain an interest in and actively seek out innovations through collaborations within and outside the organization as necessary to benefit the project and/or department.

We are looking for

The successful candidate will hold a science degree in biology/ biochemistry/ microbiology/ biotechnology or a related field. Experience of working in commercial biopharmaceutical environment and preparing technical documentation such as SLPs, SOPs, protocols, reports etc. is advantageous. They should be knowledgeable in microbial fermentation process development and scale-up, handling of pathogenic/non-pathogenic microorganisms, molecular techniques, in-vitro testing of vaccines, microbial assay development, Design of Experiment methodology. Experience of leading projects/teams and understanding of process validation, working in regulated areas and awareness of Health & Safety regulations would be beneficial. Equally important requirements are a conscientious approach to work, precise attention to detail and good communication skills.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here