Careers

Porton Biopharma has approximately 350 staff in a wide range of roles from those working in our pharmaceutical manufacturing plants, through to our quality and scientific development groups.  All focused on developing & manufacturing life-saving products that make a real difference to patients’ lives.

We are always looking for people, ranging from those with a general interest in science & technology, to ones with higher qualifications and/or experience.

This currently includes various vacancies for pharmaceutical production staff and supervisors to support our continued growth.  So if you are a motivated person who is interested in working in a high-tech environment as part of a dynamic team, then there could be a role for you.

 

 

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WE OFFER…

A friendly environment working alongside committed teams of people, who will be happy to share their knowledge and experience to allow you to develop your potential, with benefits that include:

  • a competitive salary
  • the necessary training
  • a pension scheme
  • 30 days annual leave
  • a canteen, gym and an active sports & social club
  • free on-site parking

With ongoing investment into the company and plans to increase our workforce, we are committed to being a leading life-science company that really makes a difference to patients’ lives.

To see the sort of  people that we ‘re looking for, the  Staff Profiles page has short interviews with current staff giving an overview of just some of our roles.

CURRENT VACANCIES…

PBL only accept CV’s from Recruitment Agencies with whom we have agreed Terms & Conditions.

A list of our current vacancies shown below.

To apply for a specific vacancy applicants should  send a covering letter quoting the Job Reference Number, a copy of their CV, together with a supporting statement referring to both the Job Description and Person Specification.

However, we also welcome applications from people with transferable skills that are looking for that next challenge and to develop their career.  To be considered for up-and-coming roles please send a covering letter indicating why you want to join PBL and in which area your career aspirations lie (Engineering  / Production  / Quality etc.),  along with a CV detailing your skills and experience which we can keep on file for when a suitable position becomes available.

All applications should be sent to recruitment@portonbiopharma.com.

WORK EXPERIENCE

As a business, we recognise the value that offering work-experience placements can bring and typically offer up to 4  one-week placements each year, usually in June.   All applicants must be over 16 years of age at the time of the placement, and will be chosen following a selection process.

If you are interested in applying, then send an email and covering letter stating your interest and giving reasons why we should choose you to business@portonbiopharma.com  Applications must be received by the end of November in order to be considered for the following summer’s places.

 

PBL368 Production Technician - Seed Unit

Salary: Starting salary £20,220 per annum/pro rata negotiable dependent upon experience + 10% shift allowance

Closing Date: 30th August 2019

Reference Number: PBL368

Job Purpose / Summary

 The successful candidate will assist the FPP Support Team with the routine tasks that are performed within the process hall including cleaning, environmental monitoring, water sampling, calibration checks, ordering and maintaining supplies of consumables. Some driving will be required to ensure delivery of samples and good communication with other members of staff.

We are looking for…

The successful applicant will preferably have prior experience of working within a GMP environments and have an interest in microbiology and the enthusiasm to pursue a career working in pharmaceuticals. You will have the ability to keep clear and accurate records and to follow written procedures as well as having excellent communication skills with a flexible approach to work.

This role can be taken as a part-time or full-time position; however this must include Saturday and Sunday working.

 The post holder will …

  • Function as part of the team responsible for cleaning of the FPP Main Process Hall, Seed Production Unit and periphery.
  • Assist with Environmental Monitoring of the FPP Main Process Hall.
  • Assist with the water sampling of the FPP Main Process Hall.
  • Assist with transporting product, materials, and equipment to and from the Main PHE site.
  • Assist with the ordering, stocking up, and maintenance of consumables.
  • Ensure compliance is maintained during manufacture and that PBL policies and procedures are applied when necessary.
  • Liaise with Pharmaceutical Stores, Quality Control and EMCOR to ensure the unit stays within compliance and is ready for operations when required.
  • Ensuring training is completed and up to date for their required area of work.

For further information or an informal discussion about the post, please contact:

Recruitment@portonbiopharma.com

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their covering letter to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

 

To download the job description please click here

PBL500 QC Sample Reception Data Entry Technician

Salary: Starting salary £20,200 per annum pro rata negotiable dependent on experience

Closing Date: 30th August 2019

Reference Number: PBL500

Job Summary…

A vacancy exists for an enthusiastic team member in Sample Reception, within Quality Control. We are looking for someone to work 16 to 20 hours per week, ideally in the mornings to early afternoon 5 days a week. The successful candidate will be comfortable dealing with many internal customers and working within deadlines. Tasks in Sample Reception include receiving and logging samples requiring testing on a database from all areas of PBL, to track their testing and ensuring that all documentation is filed and archived correctly.

The post holder will…

  • Communicate with internal customers to ensure samples are processed accurately and efficiently and provide results when they become available and liaise when testing schedules change.
  • The post holder will be responsible for receiving, checking and logging all samples onto a specific database
  • Distribute test samples to specific QC labs or despatching samples to external test facilities
  • Receive QC forms for splitting, filing and distribution to batch review or named individual
  • Check the database to answer queries on sample progress or status.
  • Responsible for cleaning and monitoring of equipment in QC reception area to Standard Operating Procedure.
  • When required train any member of staff in the daily routine of the reception area and use of the database.
  • Ensure the Examination Request Form archiving system is maintained and up to date at all times.
  • Work effectively within the quality control team and organise work schedule to ensure adequate cover for sample reception.
  • Support Quality Control activities when required.
  • Initiate Non-Conformances and support investigations when required.
  • To maintain an up to date awareness of regulatory and scientific advances by attending training courses or meetings that contribute to the efficiency and effectiveness of staff training and working practices that are beneficial to the post holder’s development.
  • In line with overall responsibilities, to perform any other tasks assigned, or objectives set, by the line manager.
  • To undertake all work in accordance with Porton Down Code of Safety Practice and Quality Systems
  • To comply with all Porton Biopharma Limited policies and procedures

 We are looking for...

A candidate who holds GCSE qualifications in Math’s, English and Science or equivalent. The post holder will have an eye for detail, good organization skills and ideally have experience in an administrative environment, particularly record keeping.

Experience of working in a regulated environment such as GMP or ISO would be advantageous as would safety awareness of COSHH and risk assessment.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

 

To download the job description please click here

PBL379 Head of Quality Operations

Salary: Competitive salary dependant on experience

Closing Date: 30th August 2019

Reference Number: PBL379

Job Purpose

We are currently looking for someone to lead the Quality Operations teams to successfully deliver products to the required Quality standard, on time and in full. This requires a highly motivated Quality Professional with drive and passion to inspire and deliver through the managers that report to them.

The post holder will oversee and lead the Product Release teams in the delivery of products, and will be responsible for a team of circa 40 people with 4-5 direct reports.

The post holder will

  • Act as the Quality Leader within the business and manage the Product Quality teams to be a High performing team that ensures:
  • Timely review of all Batch Manufacturing Documents to ensure compliance with EU GMP and the Product Specification File/marketing authorisation (or other where relevant).
  • Ability to review and approve documents within the QMS and to ensure the requirements of Eudralex and CFRs are met.
  • The Quality culture is embedded in daily tasks and activities with emphasis on Data Integrity.

The successful candidate will have extensive QA and management experience within the medicinal products/ pharmaceutical industry as well as Leadership qualities including inspiring change, drive for results, collaborative working and personal improvement.

Experience in Sterile manufacture and biopharmaceuticals is desirable.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL531 Senior Analytical Scientist & Quality Management System Coordinator

Salary: Cira £30,000-£37,000.00, dependant on experience

Closing Date: 13th September 2019

Reference Number: PBL531

Job Purpose………………..

The Development Group forms the overall R&D function of Porton Biopharma Ltd. The Development Group is organised into 4 core operational teams responsible for in vitro culture processes, downstream processes, analytical method development and product development respectively. This is a dual role in which the post holder will work operationally within the analytical team as a senior analytical scientist working to develop analytical methods and conduct analytical testing of products and processes under development. In addition, coordinate activities towards implementation and management of the Quality Management System (QMS) across the development group in line with requirements of ISO9001:2015. The primary role being laboratory based and progression of technical projects the secondary role to support and coordinate the QMS.

The post holder will…………

The successful candidate will be involved in routine testing of samples provided by other groups within PBL and leading the development of analytical methods for the analysis of biopharmaceutical products. He or she will also be involved in developing, optimising, validating and implementing analytical methods and technical transfer of assays to QC.

The post holder will be expected to work to a testing schedule and meet determined deadlines using established methods; evaluate and optimise novel approaches; plan their own work; train and support junior members of staff; present and provide written and verbal updates and follow departmental policies and procedures. In addition, the role will require the individual to improving existing methodology, develop novel and new analytical methods, products and technologies.

The post holder will be involved in supporting the implementation, management, maintenance and continuous improvement of the ISO9001:2015 Quality Management System. This will include coordinating and documenting the internal audit system, reviewing QMS efficiency, writing quality documents and ensuring ongoing compliance with ISO9001:2015 and other industrial regulations.

 We are looking for……………….

Education to at least degree level in a relevant subject is essential as are a basic understanding of protein chemistry and knowledge of analytical tests performed on proteins. The post holder must have general laboratory experience, preferably direct experience of working in an analytical laboratory outside the academic setting, where he or she will have been employing chromatography techniques. Experience of using UV/Vis spectrophotometers and/or microplate readers to perform assays as well as performing gel electrophoresis techniques would also be desirable. The role requires good people management skills as well as the ability to manage multiple technical projects with the aim of meeting set deadlines.

The successful candidate must have experience of working to the requirements of a quality system such as ISO9001:2015 or GMP. Experience of maintaining, managing, implementing and improving QMS systems is also required. Good management of time and multiple tasks as well as meeting tight deadlines is also required.

Applicants must demonstrate attention to detail and an enthusiasm for analytical work. Good written and verbal communication skills and proficiency in MS Office and other relevant software are also required.

The successful candidate will also be expected to maintain up-to-date knowledge of ISO, ICH guidelines, Federal Codes and other regulatory guidance relating to analytical methods and therefore awareness of the requirements of European and US cGMPs is highly desirable.

For further information or an informal discussion about the post, please contact:

Dr Alka Bishop (alka.bishop@portonbiopharma.com) or Stuart Smith (stuart.smith@portonbiopharma.com)

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL530 Mechanical Maintenance Technician Apprentice

Salary: £16000.00

Reference Number: PBL530

Job Summary…

Working within the GMP Engineering team you will undertake all aspects of both planned and reactive maintenance on process fermentation vessels, centrifuges, CIP skids, autoclaves, aseptic filling lines and the Effluent treatment plant along with the site utilities of clean steam, plant steam and purified water. The tasks will be varied from full annual servicing to routine daily checks of PBL equipment and utilities.

With support you will be ensuring all PBL production equipment and utilities are maintained at all times. You will become a valued member of the GMP engineering team working to minimise disruption to manufacturing activities.

We are looking for…

Applicants should hold 5 GCSEs (Grades A-C) including Math’s, English and Science or GNVQ equivalent and NVQ Level 3 in a relevant subject would be desirable but not essential. The successful applicant should have good organisational skills; be proactive and able to work on your own or as part of a team; accurate and clear record keeping skills; have a diplomatic and tactful approach to colleagues and good communication skills; the ability to follow written procedures as well as having excellent communication skills with a flexible approach to work.

The post holder will…

Undertake work in accordance with the PBL’s Health and Safety policies and procedures and to work within any Quality Systems that are applicable to the site to comply with all PBL policies and procedures.

Be responsible for reactive maintenance to minimise loss of production.

Routine water samples following company SOP’s

Be maintaining PBL equipment and utilities.

Be working with Engineering, Production and QA to troubleshoot critical failures of equipment or utilities.

Be conducting daily maintenance tasks

Be looking after contractors when on site and ensuring they are operating according o he RAMS provided.

Complete all paperwork as required to meet GMP standards.

Job Summary…

Working within the GMP Engineering team you will undertake all aspects of both planned and reactive maintenance on process fermentation vessels, centrifuges, CIP skids, autoclaves, aseptic filling lines and the Effluent treatment plant along with the site utilities of clean steam, plant steam and purified water. The tasks will be varied from full annual servicing to routine daily checks of PBL equipment and utilities.

With support you will be ensuring all PBL production equipment and utilities are maintained at all times. You will become a valued member of the GMP engineering team working to minimise disruption to manufacturing activities.

We are looking for…

Applicants should hold 5 GCSEs (Grades A-C) including Math’s, English and Science or GNVQ equivalent and NVQ Level 3 in a relevant subject would be desirable but not essential. The successful applicant should have good organisational skills; be proactive and able to work on your own or as part of a team; accurate and clear record keeping skills; have a diplomatic and tactful approach to colleagues and good communication skills; the ability to follow written procedures as well as having excellent communication skills with a flexible approach to work.

The post holder will…

Undertake work in accordance with the PBL’s Health and Safety policies and procedures and to work within any Quality Systems that are applicable to the site to comply with all PBL policies and procedures.

Be responsible for reactive maintenance to minimise loss of production.

Routine water samples following company SOP’s

Be maintaining PBL equipment and utilities.

Be working with Engineering, Production and QA to troubleshoot critical failures of equipment or utilities.

Be conducting daily maintenance tasks

Be looking after contractors when on site and ensuring they are operating according o he RAMS provided.

Complete all paperwork as required to meet GMP standards.

Due to the nature of the work carried out at Porton Biopharma Ltd we are only accepting applications from persons aged 18 and over

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL525 Electrical Technician Apprentice

Salary: £16000.00

Reference Number: PBL525

Job Summary…

Working in the Engineering team you will undertake all aspects of electrical controls and instrumentation maintenance on process fermentation vessels, centrifuges, CIP skids, Effluent treatment plant along with the site utilities of clean steam, plant steam, purified water and Data acquisition systems. Tasks to be undertaken will be varied from full annual servicing to routine daily checks.

Working as part of a multi skilled team you will be ensuring all PBL production equipment and utilities are maintained at all times. You will become a valued member of the GMP engineering team working to minimise disruption to manufacturing activities reducing downtime and improving equipment reliability.

We are looking for…

Applicants should hold 5 GCSEs (Grades A-C) including Math’s, English and Science or GNVQ equivalent and NVQ Level 3 in a relevant subject would be desirable but not essential. The successful applicant should have good organisational skills; be proactive and able to work on your own or as part of a team; accurate and clear record keeping skills; have a diplomatic and tactful approach to colleagues and good communication skills; the ability to follow written procedures as well as having excellent communication skills with a flexible approach to work.

The post holder will…

Instigate and manage small improvement projects, in particular those relating to control and automation systems.

Be responsible for the troubleshooting on critical control and automated equipment to ensure he smooth operation of production to minimise production downtime.

Be maintaining PBL equipment and utilities.

Be working with Engineering, Production and QA to troubleshoot critical failures of equipment or utilities.

Be conducting daily maintenance tasks

Be looking after contractors when on site and ensuring they are operating according o he RAMS provided.

Complete all paperwork as required to meet GMP standards.

Due to the nature of the work carried out at Porton Biopharma Ltd we are only accepting applications from persons aged 18 and over.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL524 QC Apprenticeships x 2

Salary: £16000.00

Reference Number: PBL524

Job Purpose / Summary

To support the Quality Control Bacteriology and Analytical Technical Services Unit, which performs specialist microbiological biochemical testing service to assist licensed pharmaceutical manufacture at PBL, Porton Down, in compliance with cGMP

The post holder will…………

  • Ensure the environment in departmental laboratories is maintained to GMP standards of cleanliness, tidiness and audit preparedness
  • Responsible for cleaning and monitoring of equipment in the department, for example:
  • Housekeeping duties to ensure the smooth running of the department, for example:
  • Maintaining stock inventories and monitor stock levels, for example
  • Decontamination and disposal of laboratory waste, for example:
  • Preparation of equipment for calibration, validation, servicing and maintenance
  • Support QC Technologists in their role in the testing of production samples, for example:
  • GMP requirements, for example:
  • Health & Safety work in according to the safe requirements of the Laboratory
  • Training
    • Attend Wiltshire College and complete all of the Knowledge Training in a timely manner
    • Complete all of the required Training and maintain a portfolio in accordance with the Apprenticeship requirements.
    • Attend all assessor visits and cooperate with the requirements and support offered

Other

You will carry out any other duties as may reasonably be required by the directorate.

The job description and person specification may be reviewed on an ongoing basis in accordance with the changing needs of the organisation.

Due to the nature of the work carried out at Porton Biopharma Ltd we are only accepting applications from persons aged 18 and over.

We are looking for

Two enthusiastic, hard-working and diligent individuals with 4 good GCSE’s, or relevant experience, who are looking to join a growing company with exciting career development prospects.

To apply for this position please submit your CV and covering letter (to pbl.recruitment@portonbiophatrma.com) using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL526 Production Technician Apprentice x2

Salary: Starting salary £16,000

Closing Date: 30th September 2019

Reference Number: PBL526

Job Summary…

The Product Support Unit is a GMP manufacturing facility involved in the preparation of equipment and reagents used during filling, freeze drying and finishing of pharmaceutical products. Working in a highly regulated environment, you will be working within a small team involved in the production of pharmaceutical products and the operation of production equipment used in the preparation of components.

We are looking for…

Applicants should hold 5 GCSEs (Grades A-C) including Math’s and English, a GCSE in a science subject would be desirable but not essential. The successful applicant should have an interest in microbiology and the enthusiasm to pursue a career working in pharmaceuticals. You will have the ability to keep clear and accurate records and to follow written procedures as well as having excellent communication skills with a flexible approach to work.

The post holder once trained will

Be able to perform, when applicable, activities relating to the cGMP manufacturing of pharmaceutical products, i.e. assist with the preparation of media, buffers and reagents, both sterile and non-sterile. The successful applicant will be competent in and perform aseptic techniques and will perform a wide range of routine and non-routine technical procedures. Day to day tasks also include maintaining the facility via specialist cleaning procedures, monitoring environmental conditions and performing aseptic processes within a cleanroom environment.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Note:- Due to the nature of the work carried out at Porton Biopharma Ltd we are only accepting applications from persons aged 18 and over.

Hours will be 37.5 per week. This includes 20% study time (day release)

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL460 Compliance Engineer

Salary: Starting salary £29,355 negotiable dependent upon experience

Reference Number: PBL460

Job Purpose…

The Engineering group provides all engineering support within the highly regulated GMP production facilities at Porton Biopharma Ltd. The group includes engineering functions provided by predominantly chartered professional engineers specialising in clean rooms, GMP critical utilities, production equipment, pharmaceutical facilities, and capital works delivery.

 The post holder will…

  • Lead the investigation and root cause analysis determination of deviations as part of a multi-disciplinary team
  • Support engineering colleagues to complete continuous improvement actions and the timely completion of compliance activities
  • Assist in fault finding following failures or performance issues and the coordination of planned and corrective engineering activities such as maintenance and calibration
  • Monitor the performance of critical systems supporting manufacturing including HVAC and critical utilities

 We are looking for…

The ideal candidate would have experience of working under a Quality Management System and to the requirements of cGMP. Previous experience of aseptic processing and/or biopharmaceutical manufacture is also desirable. The role would suit a new or recently qualified individual aiming to join the biopharmaceutical industry or a candidate with existing experience in the industry looking to develop a career within Engineering. The successful candidate will be educated to A/AS Level or hold an equivalent academic or vocational qualification.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL528 Unit Manager Immuno

Salary: Circa £29000.00 - £43000.00 per annum, negotiable dependant on experience

Closing Date: 27th August 2019

Reference Number: PBL528

Job Summary………………..

 Unit Managers are located at various manufacturing centres at Porton Down. The facility is an FDA and MHRA licensed GMP manufacturing facility which produces therapeutic products using various chemical and natural techniques.

The post holder will…………

 Manage and supervise the output of a small team in a high-pressure manufacturing environment.

Work in a highly regulated pharmaceutical manufacturing area.

Ensure that the various work areas are maintained at the highest state of readiness at all times.

Ensure that the daily activities of staff are coordinated with other team members.

Work within a GMP quality system.

Ensure that documentation is completed within the legal frameworks.

Take responsibility for Non- Conformances, CAPA, Risk Assessments and Change Controls for the area and ensure SOPs and BMRs are available for use.

We are looking for……………….

 The successful candidate will be self-motivated, well organised and have been educated to degree level or equivalent. Previous experience managing a small team is essential. The candidate will be part of a team responsible for a series of tasks in a number of different areas.

For further information or an informal discussion about the post, please contact:

Brian Lumby Deputy Head of Production by email brian.lumby@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL527 Unit Manager PPC

Salary: Circa £29000.00 - £43000.00 per annum, negotiable dependant on experience

Closing Date: 27th August 2019

Reference Number: PBL527

Job Summary………………..

 Unit Managers are located at various manufacturing centres at Porton Down. The facility is an FDA and MHRA licensed GMP manufacturing facility which produces therapeutic products using various chemical and natural techniques.

The post holder will…………

 Manage and supervise the output of a small team in a high-pressure manufacturing environment.

Work in a highly regulated pharmaceutical manufacturing area.

Ensure that the various work areas are maintained at the highest state of readiness at all times.

Ensure that the daily activities of staff are coordinated with other team members.

Work within a GMP quality system.

Ensure that documentation is completed within the legal frameworks.

Take responsibility for Non- Conformances, CAPA, Risk Assessments and Change Controls for the area and ensure SOPs and BMRs are available for use.

We are looking for……………….

 The successful candidate will be self-motivated, well organised and have been educated to degree level or equivalent. Previous experience managing a small team is essential. The candidate will be part of a team responsible for a series of tasks in a number of different areas.

For further information or an informal discussion about the post, please contact:

Brian Lumby Deputy Head of Production by email brian.lumby@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL488 QC Technologist

Salary: Starting salary £22,660, negotiable dependent upon experience plus 7% shift enhancement

Closing Date: 27th August 2019

Reference Number: PBL488

Job Purpose…

A crucial part of the pharmaceutical production process is undertaken by the Quality Control Department, which performs chemical and biochemical testing to ensure that the manufactured product is safe, efficacious and fit for patient use as a pharmaceutical material. The QC Technologist is primarily responsible for testing of in process and finished product samples, to defined specifications, while ensuring that work performed within the laboratories is carried out in accordance with the statutory requirements of current GMP and corporate statutory health and safety requirements. The QC Technologist is also responsible for the authoring of technical documentation and liaising with external laboratories to arrange contract testing of products.

The post holder will be required to work a shift rotation. This rotation includes 2 weeks out of 8 weeks where the shift is 2-10pm and potential weekend working (schedule dependent).

We are looking for…

A full time, permanent QC Technologist to perform analyses within the QC department of our pharmaceutical manufacturing facilities. The ideal candidate will have a degree in Chemistry, Biochemistry or related subject. The successful candidate will have working knowledge or experience within a regulated or cGMP environment. Experience in biopharmaceutical analysis and analytical chemistry is desirable in one of the following areas; enzyme analysis, physical testing, UV-Vis or pharmacopoeia testing within a GMP compliant QC laboratory. Other key skills include the ability to work to deadlines, technical report writing, problem solving, the ability to work as part of a project team and good computer literacy.

The post holder will…

  • Ensure analysis and recording of QC and stability testing is performed in compliance with the statutory requirements of cGMP.
  • Be responsible for testing in process and finished product samples to ensure that they meet the specifications established in the product licence and internal Porton Biopharma specification documents.
  • Be responsible for writing Standard Operating Procedures and their associated risk assessments to ensure that those tasks are performed safely and other quality documents e.g. change controls, validation reports, non-conformances and CAPAs where appropriate.
  • Organise and liaise with external testing laboratories to arrange correct and on time testing to meet production deadlines or suppliers of equipment or chemicals.
  • Organise and liaise with internal departments such as validation, pharms stores and QA where required.
  • Maintain an up-to-date awareness of regulatory and scientific developments via courses, meetings and literature.
  • Undertake work in accordance with Porton Biopharma’s Code of Safety Practice and Quality Systems.
  • Maintain training records.
  • Cleaning of laboratories.
  • Performing maintenance and calibration of equipment.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL 503 Process Development Scientist

Salary: £23,500 per annum

Closing Date: 21st August 2019

Reference Number: PBL503

Job Purpose…

The Development Group plays a key role in the translational research activities of the site. The post-holder will provide scientific and technical assistance in the area of Downstream Processing to projects involved in the development of processes for the manufacture of biopharmaceutical products.

The post holder will…

The successful applicant will provide scientific and technical assistance in the area of Downstream Processing to projects involved in the development of processes for the manufacture of biopharmaceutical products. Tasks will include the operation of protein purification equipment at various scales utilizing a variety of separation techniques. The post holder will have a keen interest in the area of protein purification, process development, scale up and validation. They will be required to work in multi-disciplinary teams and contribute to the generation of experimental designs, presentation of work to internal and external customers and the preparation of technical reports and project proposals. The post holder will contribute to process validation and manufacture problem solving activities and will play a supporting role in the technology transfer activities relating to the development and/or manufacture of biopharmaceutical products internally or between Porton Biopharma and its collaborators/customers.

We are looking for…

The successful applicant should hold a science degree in biological science or biochemistry. They should have a demonstrable interest in Downstream processing techniques, development and scale up, and experience is desirable but not essential.

Equally important requirements are a conscientious approach to work, precise attention to detail, ability to work independently and good communication skills. The post-holder will be part of a small flexible team reporting to the Development Scale up Lead.


For further information or an informal discussion about the post, please contact: Ros Brehm 01980 551587.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL467 Asset Management Administrator (Fixed Term 6 months)

Salary: £23,735 per annum

Closing Date: 19th August 2019

Reference Number: PBL467

Job Summary...

The Pharmaceutical Engineering group provides all engineering support within the highly-regulated Development and Production (D&P) facilities at PHE Porton Down. The group includes engineering functions provided by professional engineers specialising in clean rooms, GMP critical utilities, production equipment, pharmaceutical facilities, and capital works delivery.

The post holder will…

Be part of the PBL Asset Management Team responsible for the on-boarding of PBL assets, use of Excel spreadsheets for reporting purposes, KPI’s and administration of work orders.

We are looking for…

Excellent written, verbal, technical and personal communication skills are necessary, as this role will be required to communicate to audiences from a wide range of disciplines. Experience of Oracle and computerised maintenance management systems such as Maximo is desirable.

Applicants should have a good appreciation of quality systems and legislative requirements associated with provision of engineering within a cGMP environment.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.

For further and informal discussion about the post, please contact.... Gary Duncan - 01980 551776

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

To download the job description please click here

PBL523 Contractor Coordinator

Salary: Circa £22,660 - £35,175, negotiable dependant on experience

Closing Date: 23rd August 2019

Reference Number: PBL523

Job Summary…

The Contractor Coordinator is responsible for:

  • Coordination of all contracted engineering activities for PBL
  • Administration of Service Contracts and Purchase Orders
  • Management of Engineering contractors while on site

The Contractor Coordinator will interface with the wider Engineering group, and other PBL functions, to ensure compliance with Good Manufacturing Practice.

The post holder will…

  • Coordinate the delivery of contracted engineering activities with the Engineering Scheduler and other key stakeholders to establish suitable periods of non-production activities, thereby maximizing production output whilst maintaining regulatory and legislative compliance of the production facilities.
  • Manage contractors providing specialist maintenance and calibration services in order to maintain the high level of regulatory compliance essential to PBL’s manufacturing of pharmaceutical products.
  • Coordinate with Production, QA, Engineering Management and relevant key stakeholders to ensure all necessary maintenance and calibration documentation is available to support Production activities, including formal facility release following Engineering Shutdowns.
  • Provide commercial support in managing the individual contracts, orders and budgets associated with all specialist maintenance and calibration activities being undertaken for PBL.
  • Ensure all contracts are in compliance with PBL/PHE/DH procurement processes.

 We are looking for someone with...

  • A minimum of 2 A Levels at grade ‘B’ or higher, or equivalent level qualification, in relevant subjects; or significant experience of working at a similar level in specialist area.
  • Experience of planning and undertaking Engineering activities.
  • Experience of working within a recognized Quality System.
  • Effective leadership, planning, and time management skills.
  • Experience of dealing with internal stakeholders, negotiating and agreeing work programs, reporting progress, and dealing with issues to ensure on-time delivery and customer satisfaction.
  • Knowledge of Engineering Health & Safety legislation, and its application to Engineering Operations & equipment asset management.
  • Accurate and clear record keeping skills.
  • Good communication skills.
  • The ability to take a diplomatic and tactful approach with stakeholders.
  • Excellent organizational skills.
  • A focus on putting quality first.
  • Confidence in using common Microsoft Office programs (such as Word, Excel, Outlook, etc.) on a daily basis.
  • Good numeracy skills.

 

  • Basic project planning skills.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

To download the job description please click here

PBL433 QC Micro Technologist

Salary: Circa £23,735 per annum, negotiable dependant on experience

Reference Number: PBL433

Job Summary………………..

The post holder will be part of the QC Bacteriology Technical Services team and assist with activities which include the following:

To undertake and perform microbiological QC analyses in the Quality Control Bacteriology Technical Services Unit, which provides specialist microbiological testing services in support of licensed pharmaceutical manufacture at PBL, Porton Down, in compliance with cGMP.

The post holder will have…………

  • Knowledge and experience of microbiology gained in a laboratory or similar environment.
  • An understanding of GMP and quality systems
  • Able to work methodically and to strict deadlines
  • To perform routine testing within the microbiology laboratory, on a day to day basis, of the Bacteriology Technical Services Unit.
  • Good understanding of QC microbiological assays and QC laboratory systems
  • Confident to train junior staff in processes and procedures.

 We are looking for……………….

An applicant who has good interpersonal skills and able to work as part of a team and is methodical and reliable with the ability to think clearly, the ability to learn and able to respond to changes in schedule and demands. The applicant will need to have knowledge and experience of microbiology gained in a laboratory or similar environment and ideally have experience of working in a Good Manufacturing Practice GMP or similarly regulated environment.

To apply for this position please submit a CV and cover letter to recruitment@portonbiopharma.com using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL444 QC Micro Technologist

Salary: Cira £23,735.00 per annum, negotiable dependant on experience

Reference Number: PBL444

Job Summary………………..

The post holder will be part of the QC Bacteriology Technical Services team and assist with activities which include the following:

To undertake and perform microbiological QC analyses in the Quality Control Bacteriology Technical Services Unit, which provides specialist microbiological testing services in support of licensed pharmaceutical manufacture at PBL, Porton Down, in compliance with cGMP.

The post holder will have…………

  • Knowledge and experience of microbiology gained in a laboratory or similar environment.
  • An understanding of GMP and quality systems
  • Able to work methodically and to strict deadlines
  • To perform routine testing within the microbiology laboratory, on a day to day basis, of the Bacteriology Technical Services Unit.
  • Good understanding of QC microbiological assays and QC laboratory systems
  • Confident to train junior staff in processes and procedures.

 We are looking for……………….

An applicant who has good interpersonal skills and able to work as part of a team and is methodical and reliable with the ability to think clearly, the ability to learn and able to respond to changes in schedule and demands. The applicant will need to have knowledge and experience of microbiology gained in a laboratory or similar environment and ideally have experience of working in a Good Manufacturing Practice GMP or similarly regulated environment.

To apply for this position please submit a CV and cover letter to recruitment@portonbiopharma.com using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL522 Senior Production Technician - FPP (x6)

Salary: Starting salary £21,000 per annum, plus 30% shift enhancement

Reference Number: PBL522

Job Purpose…

This is a shift working role which will attract a salary enhancement once appointed. This Senior Production Technician post is located at Porton Down in the Fermentation Process Plant (FPP) current Good Manufacturing Practice (cGMP) pharmaceutical manufacturing facility. This facility produces therapeutic products by bacterial fermentation followed by initial phase downstream processing.

Therapeutic products produced at Porton are licensed and marketed for worldwide distribution. The FPP is undergoing significant investment and expansion as production is being increased to meet product demand.

We are looking for…

An applicant who has GCSE’s in Maths, English and Science or equivalent qualifications. In addition, they should also be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. Candidates should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. They should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should be able to work effectively as part of a team, be proactive and able to work on their own initiative when required.

The post holder will…

Work a shift pattern which covers 24-hour, 7 day working. They will report to the Production Supervisor and will support the Production Supervisor to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements.

This role will involve undertaking a varied range of tasks, from preparation and use of operational equipment such as large scale fermenters and centrifuges, to preparation, completion, and review of Quality documentation. Full training will be provided.

Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information about the post, please contact: recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL521 Senior Fermentation Development Scientist

Salary: Starting salary £28,000 – £33,000 per annum, negotiable based on experience

Closing Date: 30th August 2019

Reference Number: PBL521

Job Purpose…

The Development is a part of Porton Biopharma and is a development and technology transfer group playing a key role in the translational research activities of the site, developing manufacturing processes and associated analytical methods for use in the cGMP production of biotherapeutics and healthcare interventions. The projects may comprise of the development of research designs and/or the improvement of existing commercial processes.

The post-holder will contribute to the income generating activities of the Upstream Process Development Team by providing technical support in the development of production processes for biopharmaceutical products.

The post holder will…

Provide scientific and technical specialism in the area of Upstream Process Development to the projects involved in the development of new products and characterisation/ improvement to the existing biopharmaceutical products. They will be required to work in multi-disciplinary teams, leading to deliver key objectives. They will contribute to the generation of experimental designs, performing experimental work, presentation of work to the customers and the preparation of scientific publications, technical reports and project proposals. The post holder will contribute to process validation and manufacture problem solving activities and will play a key role in the technology transfer activities relating to the development and/or manufacture of biopharmaceutical products internally or between Porton Biopharma and its collaborators/customers.

The post holder will be responsible for training staff within the area of specialism and supervising laboratories ensuring that work is undertaken to Porton Biopharma quality and safety policies. When required, they will work to the requirements of European and US cGMPs. Additionally, the post holder will be required to maintain an interest in and actively seek out innovations through collaborations within and outside the organization as necessary to benefit the project and/or department.

We are looking for…

The successful candidate will hold a science degree in microbiology/ biotechnology or related field and a higher qualification (PhD or MSc) is desirable. Experience of working in commercial biopharmaceutical environment and preparing technical documentation such as SLPs, SOPs, protocols, reports etc. is essential. They should be knowledgeable and experienced in microbial fermentation process innovations, development and scale-up, handling of pathogenic/non-pathogenic microorganisms, molecular techniques, in-vitro testing of vaccines, microbial assay development, Design of Experiment methodology. Experience of leading projects/teams and understanding of process validation, working in regulated areas and awareness of Health & Safety regulations would be advantageous. Equally important requirements are a conscientious approach to work, precise attention to detail and good communication skills.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd to recruitment@portonbiopharma.com.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL520 Maintenance Engineer

Salary: Circa £32,000 per annum + shift allowance, negotiable dependant on experience

Reference Number: PBL520

Job Summary…

As Electrical Maintenance Technician, you will perform all Electrical activities to maintain optimum life and operation of machinery, equipment and utilities across the fermentation process at PBL. This role involves interfacing with equipment/system owners, the principle maintenance contractor, capital project managers and the Quality Departments to ensure compliance is maintained with current Good Manufacturing Practice. You will be required to be part of an existing maintenance shift pattern covering the periods of 06.00 – 14.00, 08.00-17.00 or 14.00 – 22.00 and be placed on a callout rota to support the out of hours shift engineers.

The Post Holder will…

Working within the GMP Engineering team you will undertake all aspects of both planned and reactive maintenance on process fermentation vessels, centrifuges, CIP skids and the Effluent treatment plant along with the site utilities of clean steam, plant steam and purified water. The tasks will be varied from full annual servicing to routine daily checks of PBL equipment and utilities

With support you will be ensuring all PBL equipment and utilities are maintained at all times. You will become a valued member of the GMP engineering team working to minimize disruption to manufacturing activities.

We are looking for…

A candidate who holds a City & Guilds 18th Edition Electrical or equivalent an Industry recognised qualification in Controls & Instrumentation. The successful candidate will need to have previous experience with Electrical maintenance within a regulated environment and experience of working within Quality Systems would be advantageous. It is an essential requirement of the role that the post holder have knowledge of Engineering Health & safety Legislation and its application to maintenance operations. The post holder will have good organisational skills and have a proven ability for fault investigation. They will have good communication skills with the ability to follow written procedures and be able to build effective working relationships both internally and externally of the business and be proactive and able to work on their own initiative.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL519 Refrigeration Technician

Salary: Circa £32,000.00 per annum + shift allowance, negotiable dependant on experience

Reference Number: PBL519

Job Summary…

As Refrigeration Technician you will perform maintenance and installation of PBL equipment and utilities including Cold Rooms, Walk-in Freezers, AHU’s and Air pressure systems. This role involves interfacing with equipment/system owners, the principle maintenance contractor, capital project managers and the Quality Departments to ensure compliance is maintained with current Good Manufacturing Practice. You will be required to be part of an existing maintenance shift pattern covering the periods of 06.00 – 14.00, 08.00-17.00 or 14.00 – 22.00 and be placed on a callout rota to support the out of hours shift engineers.

The Post Holder will…

Working within the GMP Engineering team you will undertake all aspects of both planned and reactive maintenance on process fermentation vessels, centrifuges, CIP skids and the Effluent treatment plant along with the site utilities of clean steam, plant steam and purified water. The tasks will be varied from full annual servicing to routine daily checks of PBL equipment and utilities

With support you will be ensuring all PBL equipment and utilities are maintained at all times. You will become a valued member of the GMP engineering team working to minimize disruption to manufacturing activities.

We are looking for…

A candidate who has experience of refrigeration maintenance ideally within the Pharmaceutical Industry and has experienced working within a regulated environment. It is an essential requirement of the role that the post holder have knowledge of Engineering Health & safety Legislation and its application to maintenance operations. The post holder will have good organisational skills and have a proven ability for fault investigation. They will have good communication skills with the ability to follow written procedures and be able to build effective working relationships both internally and externally of the business and be proactive and able to work on their own initiative.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL518 Mechanical Maintenance Technician

Salary: Circa £32000 + 20% shift allowance, negotiable dependant on experience

Reference Number: PBL518

Job Summary…

As Mechanical Maintenance Technician you will perform planned and reactive activities to maintain optimum life and operation of machinery, equipment and utilities across the fermentation process at PBL. This role involves interfacing with equipment/system owners, the principle maintenance contractor, capital project managers and the Quality Departments to ensure compliance is maintained with current Good Manufacturing Practice. You will be required to be part of an existing maintenance shift pattern covering the periods of 06.00 – 14.00, 08.00 - 17.00 or 14.00 – 22.00 and be placed on a callout rota to support the out of hours shift engineers.

The post holder will…

Working within the GMP Engineering team you will undertake all aspects of both planned and reactive maintenance on process fermentation vessels, centrifuges, CIP skids, autoclaves and the Effluent treatment plant along with the site utilities of clean steam, plant steam and purified water. The tasks will be varied from full annual servicing to routine daily checks of PBL equipment and utilities.

With support you will be ensuring all PBL equipment and utilities are maintained at all times. You will become a valued member of the GMP engineering team working to minimize disruption to manufacturing activities.

We are looking for…

A candidate who is educated to NVQ level in relevant subject or equivalent level qualification via a mechanical based apprenticeship. The successful candidate will need to have previous experience of working in a production driven environment within a highly regulated industry; experience of working within Quality Systems would be advantageous. It is an essential requirement of the role that the post holder have knowledge of Engineering Health & Safety Legislation and its application to maintenance operations. The post holder will have good organisational skills and have a proven ability for fault investigation. They will have good communication skills with the ability to follow written procedures and be able to build effective working relationships both internally and externally of the business and be proactive and able to work on their own initiative.

 Successful applicants must either hold, or be capable of obtaining, a UK government security clearance at SC level.  To obtain clearance at this level you must have been resident in the UK for the last five years, and not lived abroad for more than six months out of the last twelve.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL512 Process Validation Specialist

Salary: circa £40,000 per annum, negotiable dependant on experience

Reference Number: PBL512

Job Summary…

This role of the Process Validation Specialist is to coordinate the execution of Performance Qualification and Process Performance Qualification activities in support of PBL manufacturing activities and in accordance with Regulatory requirements.

The post holder will…

Have knowledge of Validation Life Cycle documentation deliverables and how to implement a Risk based approach is central to the skills base of this position.

The role will include the writing, review and execution of Process Validation plans, protocols and reports and the coordination of support activities to deliver on time a high standard of documentation.

The candidate will have a degree in Science or Engineering or equivalent and recognised academic achievement and have Project Management experience.

We are looking for…

The post holder will be expected to attend Project group meetings, liaise with PBL support teams, regulatory bodies and peers to establish data for inclusion into protocols and reports.

The position holder should be prepared to execute and witness Process Validation studies in line with the production schedule.

The following is a description of the main duties and responsibilities;

  • To coordinate the execution of the Validation Master Plan with respect to Process Validation activities.
  • Assess Change control documentation to determine change impact with respect to the validation requirements and report appropriately.
  • To support operational areas in the implementation of change.
  • Supports Process Validation activities.
  • Define Process Validation Strategies in conjunction with the Process Validation Lead
  • Author and review Process Validation plans, protocols and reports ensuring compliance to PBL policies and procedures.
  • Schedule and support Process Validation executions.
  • High level of technical and scientific writing required.
  • Understand and Applies statistical tools for development of protocols and data analysis for Process Validation (as per current FDA/MHRA Process validation lifecycle guidelines). Participate in Continued Process Verification Activities (CPV) including the generation of CPV plans and CPV reporting.
  • Present Process Validation documents at regulatory audits.
  • Performs process investigations with relevant departments as required.
  • Performs product and process impact assessments.
  • Participates in or Lead process and quality risk assessments.
  • Presents findings at group and at interdepartmental meetings.
  • Communicate information on current process data which may impact Process Validation.
  • Maintain and review the Product Control Strategy for all products. Understand the functional relationships that link CMA/CPP to CQA.
  • To ensure the timely completion of Deviations and the closure of CAPAs

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd to recruitment@portonbiopharma.com

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

To download the job description please click here

PBL 496 QC Stability Technician

Salary: Starting salary £20,220, negotiable dependent upon experience + 7% shift enhancement

Closing Date: 30th August 2019

Reference Number: PBL496

Job Purpose……

A crucial part of the pharmaceutical production process is undertaken by the Quality Control Department, which performs chemical and biochemical testing to ensure that the manufactured product is safe, efficacious and fit for patient use as a pharmaceutical material. To provide support for the chemical and biochemical analyses performed by QC technologists within Analytical QC department to support the manufacture of Porton Biopharma’s licensed pharmaceutical products; as required by EU Directive 91/356/EEC for GMP compliance.

The testing of in process and finished product samples, to defined specifications, while ensuring that work performed within the laboratories is carried out in accordance with the statutory requirements of current GMP and corporate statutory health and safety requirements.

The post holder will be required to work shift rotation. This rotation includes 2 weeks out of 8 weeks where the shift is 2-10pm and potential weekend working (schedule dependent).

We are looking for…

A full time, 12 month fixed term contract for QC Stability Technician to perform analyses within the QC department of our pharmaceutical manufacturing facilities. The ideal candidate will have 2 A levels in numerate or Science subjects as a minimum.

The successful candidate will have working knowledge or experience within a regulated or cGMP environment. Experience in setting up stability studies, writing stability protocols and reports. Other key skills include the ability to work to deadlines, technical report writing, problem solving, the ability to work as part of a project team and good computer literacy.

 The post holder will…

  • Completion of QC forms and associated paperwork
  • Sample delivery between the stability department and the QC laboratories
  • Data entry into Excel spreadsheets and other databases
  • Order consumables and chemicals for the laboratories
  • Archive old documents
  • Competition of Good Manufacturing Practice (GMP) paperwork
  • The collection and distribution of GxP documentation for QC
  • To ensure documentation (SOP’s, Specifications, Monographs, MSDS’s etc) within the department are current and copies are available
  • To maintain accurate records and filing systems
  • Ability to follow all Standard Operating Procedures (SOP’s)
  • Assist with housekeeping in Analytical QC
  • Disposal of toxic, hazardous and non-hazardous waste generated within Analytical QC
  • Calibration and scheduled maintenance of Analytical equipment
  • Maintain stock lists in QC Stability

For further information about the post, please contact:recruitment@portonbiopharma.com

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL498 Validation Technologist (Facilities & Utility)

Salary: Starting Salary £29,335 negotiable dependent upon experience.

Reference Number: PBL498

Job Purpose…

The Facilities Validation department supports cGMP manufacturing activities and is responsible for ensuring compliance to the cGMP guidelines on Validation activities.

The purpose of this role is to execute validation activities relating to Facilities and Utilities. This will involve coordination with Engineering, Production, QC and QA departments to ensure a timely delivery of the qualification report.

The post holder may be expected to supervise contractor resource where appropriate with responsibility to ensure adequate training and supervision is provided.

The post holder will be required to write, review and where appropriate approve validation reports prior to execution, followed by report generation. The core activities will include thermal and microbiological testing of:

  • Autoclaves (BSEN-285)
  • Depyrogenation ovens
  • Extraction Tanks
  • Centrifuges
  • Vessels
  • (but not limited to) the qualification of Facilities and Utilities.

The post holder will...

  • Generate, review (technical) and execute process validation protocols (thermal and microbiological testing)
  • Create Process validation reports
  • Use the Electronic Quality Management System (EQMS) to manage appropriate corrective action plans and report through the PBL non-conformance system, for failures/performance issues.
  • Write and review Risk assessments
  • Manage work schedule as planned by the validation schedule co-ordinator
  • Coordinate Contractor or permanent resources to deliver timely documentation in support of Process Validation activities
  • Ensure Process Validation procedures are aligned with regulatory requirements
  • Meet all internal regulatory training requirements (internal training provided)

We are looking for...

A person with at least 12 months hands-on validation experience, able to perform thermal mapping studies and write protocols and reports. A sound knowledge of the Validation Life cycle and documentation deliverables is an essential requirement.

Other
In addition to Utilities and Sterilisation validation activities the post holder will be expected to undertake any related validation activities deemed necessary by line management. This could include the generation of validation documentation in accordance with the full validation life cycle for equipment, utilities and facilities.

For further information or an informal discussion about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL465 QC Microbiology Manager

Salary: Circa £50,000 per annum

Reference Number: PBL465

Job Purpose…

The successful candidate will lead the Microbiology Department to successfully deliver quality products on time in full. This role will provide Line Management for 4 area managers supervising established teams within the Microbiology Department. The overall team equates to approximately 30 quality professionals.

The post holder will…

  • Work with other managers within the Quality team to ensure that manufacturing and quality activities are performed in compliance with all the regulations and other requirements including: The Rules & Guidance for Pharmaceutical Manufacturers' and Distributors, cGMP guidance, and other regulations governing PBL activities.
  • Lead projects and deliver required outcomes in their own specialist area.
  • Lead, motivate, coach, mentor and manage the performance and output of the Microbiology Team (including direct managerial reports) and ensure that all team objectives are met in agreed timescales.
  • Maintain and develop the local standard operating procedures to secure effective working practices as well as compliance with relevant national, European and US legislation.
  • Monitor the performance of the systems under area of responsibility using KPIs and report to management.
  • Develop and implement an ongoing Quality Improvement Plan related to the systems under area of responsibility
  • Lead the development and implementation of an ongoing Health & Safety Plan for the team to secure the right level of performance, highlight failures and make recommendations for solutions.
  • In line with overall responsibilities, perform additional tasks assigned by the line manager.

We are looking for…

A highly motivated quality professional with drive and passion to inspire and deliver through the team reporting to them. They will be educated to degree level or equivalent in an appropriate scientific discipline and a post-graduate degree in life/applied science or equivalent would be desirable. The successful applicant will be a strong manager with an up to date microbiology background and proven experience in the pharma industry. The post holder will be customer focused, deliver continuous improvement activities and be a subject matter expert for microbiological issues encountered during the manufacturing and testing of PBL licensed products. Previous experience of managing laboratory staff and associated activities is essential.

The successful applicant should be prepared to participate in out of hours on call Rota if required and be prepared to meet the requirements of manufacturing schedules which may include working out of hours or weekends.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL491 Visual Inspection Production Technician

Salary: Starting salary £20,220 per annum negotiable dependent upon experience

Reference Number: PBL491

Job Purpose…

This post is part of the Product Finishing team within PBL’s Pharmaceutical Production Unit which is responsible for duties including media and equipment preparation, assisting with purification and formulation of Erwinase Drug Substance, sterile filtration, and aseptic processing within a Good Manufacturing Process (GMP) department.

This post will involve training and qualification in the visual inspection process. Once qualified, the post will involve manual visual inspection of all Erwinase vials as part of the product finishing process. Other visual inspection processes will also be undertaken such as media simulation and lactose fills when required. The main responsibility of the role is within the visual inspection team however when time permits there will be opportunities to engage in other aspects within the production unit. The post holder will report to the Product Finishing Team Leader/supervisor.

The post holder will…

The visual inspection team performs the manual 100% visual inspection of Erwinase vials, a process which involves a visual assessment of final drug product vials and the removal of rejected material from the batch. Full training will be provided and once qualified you will work together as part of the team to undertake the visual inspection of all Erwinase batches manufactured. This activity will take up the majority of the time however there are opportunities between inspections to work alongside other production operators and become trained in other processes within the Production unit.

We are looking for…

The post holder will have a good general education and be educated to a minimum of NVQ 2 level in a relevant subject or equivalent level of qualification or significant equivalent proven experience as well as holding a GCSE in Mathematics, English & Science. The nature of this post requires individuals who can remain diligent and focused throughout the day. Candidates will have experience of working to deadlines, schedules and the ability to follow written procedures. Candidates need to have excellent attention to detail, be a good communicator and be able to work effectively as part of a team.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL407 Process Engineer

Salary: £29,355 negotiable dependent upon experience

Reference Number: PBL407

Job Summary…

The Engineering group provides all engineering support within the highly regulated GMP production facilities at PBL Porton Down. The group includes engineering functions provided by predominantly chartered professional engineers specialising in clean rooms, GMP critical utilities, production equipment, pharmaceutical facilities, and capital works delivery.

The Process Engineer is the System technical expert for all Process and Utility systems within the GMP Envelope and is responsible for identification of and managing small projects/initiatives relating to these systems and interfacing with the wider Engineering group to ensure equipment systems within the GMP envelope remain compliant with current Good Manufacturing Practice. In addition, the Process Engineer will work within an Integrated Process Team to provide operational support to the manufacture of biopharmaceutical products.

The post holder will…

Be a core member of an Integrated Process Team and will provide operational engineering support to the manufacture of biopharmaceutical products alongside other core members from the Production and Quality functions. You will have delegated responsibility from the Process Engineering Manager to design, manage and deliver process improvement projects and represent the group in the delivery of major facility expansion/refurbishment projects.

You will become the Subject Matter Expert for a variety of systems and equipment such as Autoclaves and Critical Utilities (e.g. WFI, Clean Steam, and Purified Water) within the Pharmaceutical Production Envelope. As such you will interface with key stakeholders including equipment users, capital project managers, and the site principal maintenance contractor, to ensure these critical systems remain in compliance with best industry and regulatory practice.

We are looking for…

An applicant with experience of design or operation of process or utility systems in a highly regulated industry. The ideal candidate will have existing experience in the pharmaceutical industry. The individual will be either working towards or have recently become chartered with a supporting process or chemical engineering degree.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL486 Environmental Monitoring Compliance Officer

Salary: Circa £28,000 - £30,000 per annum

Reference Number: PBL486

Job Purpose…

The purpose of this role is to provide support for the Sterility Assurance Program at Porton Biopharma. This will include compilation of environmental monitoring trend reports, managing GMP databases and preparing technical reports. The applicant will be taking a leading role in SOP review, developing sampling programs, leading investigations and providing technical support as required.

We are looking for…

A candidate who is educated to degree level or equivalent in microbiology, chemistry or pharmaceuticals who has GMP experience of working in cleanrooms, developing environmental monitoring programs through a risk-based approach and giving technical support in investigations. The candidate should have a good understanding of QC Microbiology laboratory testing, EM and Water testing, working with computer databases and be competent in programs such as MS Excel.  Applicants must have a flexible approach to working and be able to comply with SAPO regulations.

The post holder will…

  • Manage the GMP databases for water quality, clean steam quality and microbiological environmental monitoring.
  • Co-ordinate and review water quality, clean steam quality and microbiological environmental monitoring activities as required.
  • Prepare and analyse technical and numerical information from the databases and prepare trend analysis data as graphs, charts and or diagrams.
  • Investigate OOS water and environmental monitoring test results and review resulting Non-Conformances.
  • Prepare environmental summary reports of production batches and process simulations for inclusion in the batch manufacturing records.
  • Review particle monitoring data from the manufacturing areas.
  • Review and manage the environmental monitoring SOPs.
  • Liaise with production, quality and engineering services to promote GMP compliance. Review facility, utility and equipment documentation and monitoring data to prepare facility release reports.
  • Carry out facility release and other internal and external audits

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL485 QC Technologist (Monitoring and Training)

Salary: Starting salary £23,735 per annum negotiable dependent upon experience

Reference Number: PBL485

Job Purpose…

To provide specialist training in microbiological environmental monitoring methods, cleanroom gowning, aseptic practices and water sampling. The successful candidate will also be required to undertake microbiological environmental monitoring of critical pharmaceutical manufacturing operations to support the Sterility Assurance Program. To supervise, oversee, observe and qualify all production technologists and other staff where applicable, in gowning, microbiological environmental monitoring methods and water sampling.

We are looking for…

A candidate who has previous experience of working in cleanrooms, performing environmental monitoring and training of other members of staff to join the Environmental Monitoring Team within QC Biological Services. A degree in a relevant scientific discipline is desirable but not essential. The candidate should also have a good understanding of QC Microbiology laboratory testing. Applicants must have a flexible approach to working and be able to comply with SAPO regulations and must have a current valid right to work in the UK.

The post holder will…

  • Operate in compliance with cGMP.
  • Train and qualify all Production and other staff, as necessary, in the techniques and procedures for microbiological environmental monitoring.
  • Train and qualify all Production and other staff, as necessary, in water sampling.
  • Train and qualify all Production and other staff, as necessary, in procedures for gowning.
  • Oversee, supervise and observe Production and other staff undertaking environmental monitoring and water sampling to ensure continued compliance.
  • Re-qualify Production and other staff at a defined frequency, as required by GMP.
  • Plan and organise schedules for training, qualifications and observations.
  • Assess staff competence in environmental monitoring, water sampling and gowning procedures. Sign training documentation and produce certificates for trained members of staff.
  • Carry out and record microbiological environmental monitoring for critical manufacturing operations, and routine monitoring where required.
  • Input microbiological environmental monitoring and water sampling data into appropriate databases and spreadsheets.
  • Be involved in the writing and updating of Standard Operating Procedures relating to environmental monitoring and water sampling, either as the author, or by providing technical information and advice to the author.
  • Attend training courses that contribute to the efficiency of the operating systems and are beneficial to the post holder’s personal development.
  • Follow operating procedures at all times and ask for advice when necessary.
  • Undertake all work in accordance with Porton Down’s Code of Safety Practice and Quality Systems.
  • To prepare environmental summary reports of production processes for insertion into documents, reports and batch manufacturing records as part of batch release.
  • To investigate out-of-specification water and environmental monitoring test results in conjunction with the Compliance Team and review resulting Non-Conformances, participating in Ishikawa and 5-Whys investigations, where necessary.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer.

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL411 Aseptic Processing Specialist

Salary: Starting salary £29,355 negotiable dependent upon experience

Reference Number: PBL411

Job Purpose…

This position will report to the Aseptic Processing Functional Manager and will provide technical specialist support to all aseptic processing activities in the manufacture of Erwinase, Anthrax vaccine and other PBL products. The role will work cross functionally and be involved in current projects, new projects and all manufacturing activities that require aseptic processing input. It is expected that the role will typically focus on day to day aseptic processing matters within Production but may also be required to support projects designed to improve and develop PBL’s aseptic processing strategy.

We are looking for…

An individual who is educated to degree level or equivalent in a relevant discipline. The successful candidate should have a minimum of 5 years’ experience within Biopharma / Pharma aseptic GMP environments and have an in depth understanding of aseptic processing and techniques. You will need to have an understanding of regulatory requirements for biological products and experience in the implementation of new technologies and equipment into GMP manufacture and will have proven experience of generating GMP documents within a quality system. Experience of delivering specialised technical training and report writing and data trending evaluation would be desirable but not essential. The successful applicant will have a flexible approach to work and be able to deliver to schedules.

The post holder will…

  • Lead in the day to day aseptic processing of PPL’s products.
  • Support the management and development of improved and new processing techniques in the various aseptic processing activities.
  • Provide technical support to production staff involved in the various aseptic processes.
  • Provide troubleshooting and technical support into process investigations.
  • Collate and share technical information with internal and external bodies to benefit the production methods, teams and departments.
  • Perform process mapping and process efficiency trending.
  • Provide specialist training to staff in aseptic processing techniques and theory.
  • Identify, evaluate and adapt new technologies where appropriate and ensure that the production area operates to a high standard and complies with GMP and other regulatory standards.
  • Assist colleagues in providing technical specialist input as required, in developing production and technical strategies for the units, identifying new opportunities as they arise and responding to external queries and complaints.
  • Contribute to reports and assist on the preparation of presentations, publications and liaison with customers, collaborators and licensing agencies.
  • Support the Functional Manager Aseptic Processing in pursuance of strategic improvements to aseptic processing control.

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

PBL482 Senior Production Technician

Salary: Starting salary £20,220 per annum negotiable dependent upon experience

Reference Number: PBL482

Job Purpose…

This post is part of a team located within the Pharmaceutical Production Centre (PPC) which is responsible for the production of pharmaceutical products, preparation of components and the operation of production equipment. Day to day tasks include maintaining the facility via specialist cleaning procedures and monitoring environmental conditions within a cleanroom environment. Other duties also include media and equipment preparation, assisting with purification and formulation of Erwinase®, sterile filtration and aseptic processing.

We are looking for…

An applicant who has a GCSE in Maths, English and Science or equivalent qualification. In addition, applicants should be educated to a minimum of NVQ Level 2 in a relevant subject or have proven significant equivalent experience. Candidates should have an interest in working within a manufacturing environment and the quality systems associated with cGMP manufacture. The successful applicant will have good communication, writing and data entry skills and will need to have a flexible approach to work. Candidates will need to be pro-active and able to work on their own initiative and be able to work effectively as part of a team.

The post holder will…

Report to the Production Supervisors and Unit Leader to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements. This role will involve undertaking a varied range of tasks from preparation and use of operational equipment to completion of Quality documentation, full training will be provided where required.

For further information about the post, please contact:

recruitment@portonbiopharma.com

To apply for this position please submit a CV and cover letter using the criteria in the job description/person specification as sub-headings to identify how you meet each of the selection criteria and outline why you would like a career at Porton Biopharma Ltd.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

We reserve the right to close this vacancy should a suitable candidate be found.

To download the job description please click here

Flexible Working opportunities

Salary: dependant

Reference Number: PBL flexi

We are offering part-time opportunities to people who can contribute to the manufacturing of our life-saving products by providing general cleaning and support activities in our pharmaceutical production facilities, on a part-time basis.

We are looking to put together a team  and are considering what we can offer as an employer, so if you would like to contribute to our success and believe that you could play your part then we would like to hear from you.  Please send us a covering letter providing details of your typical availability and g quoting refrence PBL flexi.

PBL 223 Production Technician

Salary: Starting salary £20,220 negotiable dependent upon experience

Reference Number: PBL223

We are looking for...

Applicants should have GCSE in Maths, English and Science. In addition, candidates should be educated to a minimum of NVQ level 2 in a relevant subject or have significant equivalent proven experience. They should have an interest in working within a manufacturing environment and with the Quality systems associated with cGMP manufacture. Candidates should be able to communicate clearly, possessing good writing and data entry skills. Lastly applicants should have a flexible approach to work, be able to work effectively as part of a team, and be proactive and able to work on their own initiative when required.


The post holder will...

Assist with the varied support tasks that are performed within the FPP process hall. These tasks include environmental monitoring, water sampling, calibration checks, cleaning, laundry processing and dispatch, and ordering and maintaining supplies of consumables. Accurate completion of Quality documents will be required. Driving will also be required to ensure compliant delivery of production samples to the PBL main site. Lastly the post holder will require good communication skills to interact concisely with management, peers and junior members of staff.

He/she will support the Team Leader to meet team targets by ensuring manufacturing operations are performed in a timely and compliant manner to cGMP requirements

Successful applicants must either hold, or be capable of obtaining a UK government security clearance at SC level. To obtain clearance at this level you must have been resident in the UK for the last five years, and not have lived abroad for more than six months out of the last twelve.

Applicants are strongly advised to use the criteria in the job description/person specification as sub-headings in their application to make it clear how they meet each of the selection criteria.

Porton Biopharma Ltd promotes diversity in the workplace and is an equal opportunities employer

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